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MORE ALZHEIMER’S GENES

FIVE NEW GENES HAVE BEEN IDENTIFIED THAT ARE RELATED TO ALZHEIMER’S DISEASE, ELIZABETH TRACEY REPORTS

Five new genes related to an individual’s risk for developing Alzheimer’s disease have been found, but even if you have all five, that doesn’t mean you’ll necessarily develop the condition. Constantine Lyketsos, an Alzheimer’s disease expert at Johns Hopkins, explains.

LYKETSOS: The significant point about this new published research is that these are all genes that somewhat increase risk, but are not causative if you will about Alzheimer’s disease, and they confirm the view that we’ve had for a long time in the field that it’s a heterogeneous condition, meaning that a lot of factors have to align in a certain way and that each person goes down a particular pathway.       :24

Lyketsos says the genes help researchers look into certain biochemical pathways that may be involved in the eventual development of Alzheimer’s disease, but that none of them so far is the smoking gun conferring absolute certainty that the condition will arise. At Johns Hopkins, I’m Elizabeth Tracey.


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