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ADVANCED PROSTATE CANCER HELP

A RELATIVE OF ONE LONGSTANDING DRUG FOR PROSTATE CANCER HELPS IN ADVANCED DISEASE, ELIZABETH TRACEY REPORTS

Once cancer of almost any type has spread, or metastasized, it seems there’s little anyone can do.  Now there’s hope for advanced prostate cancer with a drug called carbazitaxel, a cousin of a drug called docetaxel that’s been in use for some time.  William Nelson, director of the Kimmel Cancer Center at Johns Hopkins, explains.

NELSON:  It was somewhat surprising that in this setting that carbazitaxel was proven to be effective.  Shrinks cancer, prolongs survival, controls symptoms, and to the degree that it will get its regulatory agency approval based on this use in prostate cancer.  So a significant advance; the target of docetaxel and carbazitaxel is the same molecular target in cancer cells.  And it is very interesting in my mind that this target is such a useful target to design drugs to interfere with for the purpose of controlling prostate cancer.  :31

This class of drugs interferes with the function of a cellular transport structure known as a microtubule. At Johns Hopkins, I’m Elizabeth Tracey.


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