INFLAMMATION AND CANCER
ANCHOR LEAD: CAN A SPECIFIC ANTI-INFLAMMATORY MEDICATION REDUCE THE RISK OF CANCER? ELIZABETH TRACEY REPORTS
A type of medication that reduces inflammation may help decrease how often someone who is genetically at risk develops basal cell cancers, a recent study found. Charles Rudin, a genetics and cancer risk expert at Johns Hopkins, says while the effect of reducing inflammation by this mechanism was small, the strategy makes sense.
RUDIN: I think it’s clear that inflammation does play a role in the process of cancer development. How it plays a role is still something that’s being worked out. One way that it almost certainly plays a role is by increasing cell proliferation. That if there’s chronic inflammation and cell turnover, that as those cells proliferate they’re apt to accumulate genetic errors that may ultimately result in a cancer. :29
Rudin says a better understanding of the inflammation and cancer development pathway would allow more targeted intervention. At Johns Hopkins, I’m Elizabeth Tracey.