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INFLAMMATION AND CANCER

ANCHOR LEAD:  CAN A SPECIFIC ANTI-INFLAMMATORY MEDICATION REDUCE THE RISK OF CANCER?  ELIZABETH TRACEY REPORTS

A type of medication that reduces inflammation may help decrease how often someone who is genetically at risk develops basal cell cancers, a recent study found.  Charles Rudin, a genetics and cancer risk expert at Johns Hopkins, says while the effect of reducing inflammation by this mechanism was small, the strategy makes sense.

RUDIN:  I think it’s clear that inflammation does play a role in the process of cancer development.  How it plays a role is still something that’s being worked out.  One way that it almost certainly plays a role is by increasing cell proliferation.  That if there’s chronic inflammation and cell turnover, that as those cells proliferate they’re apt to accumulate genetic errors that may ultimately result in a cancer.        :29

Rudin says a better understanding of the inflammation and cancer development pathway would allow more targeted intervention.  At Johns Hopkins, I’m Elizabeth Tracey.



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