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NASAL POLYPS

ANCHOR LEAD: RESEARCHERS HAVE UNCOVERED A KEY TO CHRONIC SINUS INFLAMMATION ACCOMPANIED BY POLYP FORMATION , ELIZABETH TRACEY REPORTS

Chronic infection of the sinuses  is very common, with some estimates as high as one in six people.  Perhaps up to a third of those folks will also experience an overgrowth of the tissue lining the sinuses to create polyps, which can make it very difficult to breath.  Now research led by Jean Kim, a sinusitis expert and surgeon at Johns Hopkins, may explain why polyps form.

KIM:  What we’ve identified is a biomarker for the presence of polyps.  We actually showed that this is not merely only a biomarker but actually serves as a functional mediator in the development of polypgenesis.  It is responsible for one of the key features of polyps which is hyperplasia or overgrowth, exuberant overgrowth of a very important cell involved in upper airway biology.      :30

Kim says identifying a factor involved in polyp formation may help develop clinical strategies for treatment.  At Johns Hopkins, I’m Elizabeth Tracey.



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