ANCHOR LEAD: ANALYZING TUMORS THAT HAVE SPREAD THROUGHOUT THE BODY GIVES IMPORTANT INFORMATION ABOUT HOW THEY DEVELOPED, ELIZABETH TRACEY REPORTS
Cancer cells from both the original tumor site as well as metastatic sites where the cancer has spread are helping researchers at Johns Hopkins discern the genetic changes that take place in aggressive prostate cancer. Steven Bova and colleagues have analyzed thousands of samples from men who died of prostate cancer.
BOVA: You can study the DNA in multiple sites in people with cancer that has spread throughout the body. You can look at the changes in the DNA in those cancer cells and then compare them in a single patient to each other, and you can see a pattern of what an original cancer cell in those men had. :24
Bova says such analyses shed light on the process by which a cancer spreads and suggests ways to intervene. At Johns Hopkins I’m Elizabeth Tracey