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CANCER MARKER

ANCHOR LEAD: IS CA125 AN EFFECTIVE SCREENING TOOL FOR OVARIAN CANCER?  ELIZABETH TRACEY REPORTS

CA125 is a marker found in the blood that was just used in a study screening for ovarian cancer.  Women with elevated levels were then referred for transvaginal ultrasound, and the study demonstrated that use of these two techniques together provided the most effective screening yet.  Still, Deborah Armstrong, an ovarian cancer expert at Johns Hopkins, says a more specific marker for ovarian cancer is desirable.

ARMSTRONG:  The CA125 is actually something that is shed from the surface of cells.  It can be shed from the surface of normal cells but also from ovarian cancer cells, and can be detected in the blood and almost all of us will have some level of this in the blood.  We have levels that we consider normal, and when they go above normal that can be considered a sign of cancer.  Its not necessarily, there are many benign conditions that many of us are familiar with like fibroids, endometriosis, appendicitis, any of these things can raise the CA125.               :27

At Johns Hopkins, I’m Elizabeth Tracey.


-- JHMI --
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