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MODIFYING COPD

ANCHOR LEAD: COULD CHRONIC OBSTRUCTIVE PULMONARY DISEASE BE TREATED WITH A BROCCOLI EXTRACT?  ELIZABETH TRACEY REPORTS

COPD, or chronic obstructive pulmonary disease, bears the dubious distinction of being number 4 on the big killer list in the United States, and number 3 worldwide.  And more people are developing COPD all the time, perhaps because of decreased air quality around the globe.  Now Shyam Biswal and colleagues at Johns Hopkins may have identified a potential treatment.

BISWAL:  Interestingly, one of the compounds from broccoli, sulfurophane, seems to work well in lung cells which have declined in the same antioxidant pathway as a result of chronic cigarette smoke exposure in these cell models, so there is some promise that that could be one of the drugs that we will try in clinical trials.            :18

Biswal says treatments and interventions he’s looking at are thought to help promote an antioxidant pathway in the lungs that’s known to be defective in some folks with COPD.  I’m Elizabeth Tracey reporting.


-- JHMI --
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