Health NewsFeed

Health Newsfeed

CAUSE OF ALZHEIMER’S

ANCHOR LEAD: THE MOST WIDELY ACCEPTED THEORY ON HOW ALZHEIMER’S DISEASE DEVELOPS MAY NOT TELL THE WHOLE STORY, ELIZABETH TRACEY REPORTS

A vaccine that does clear plaque from the brain doesn’t help symptoms or reduce deaths from Alzheimer’s disease, a recent study reported in the Lancet concluded.  Constantine Lyketsos, an Alzheimer’s disease expert at Johns Hopkins, says there’s one obvious interpretation of these disappointing results.

LYKETSOS:  It suggests that clearing amyloid from the brain is not the whole story.  It may be that amyloid is in fact a consequence of an unknown or poorly known process that leads to symptoms, and so clearly amyloid only had a small effect, or it may mean that by the time that patients have dementia, in other words the patients who received the therapy had a lot of brain tissue loss, that clearing amyloid was being delivered too late to be of help to them.                 :28

Lyketsos says earlier detection of amyloid plaque formation and use of a clearing vaccine may very well result in benefit.  I’m Elizabeth Tracey reporting.


-- JHMI --
Search Health NewsFeed

-----------------------------------------
Health NewsFeed Home | Hopkins Medicine Home