ANCHOR LEAD: MAXIMIZING DRUG BENEFITS IN KEEPING VIRUSES UNDER CONTROL MAY USE A SIMPLE FORMULA, ELIZABETH TRACEY REPORTS
Using a formula that’s been around for quite some time helps predict which drugs will be most effective against HIV, Johns Hopkins researchers have reported. Robert Siliciano, the study’s senior investigator, says the formula should also prove useful for infections other than HIV.
SILICIANO: Right now I think it’s a tool in drug development to tell us which drugs have the highest ability to inhibit replication, and actually could be applied to any drug used to treat any virus. In terms of HIV it may be used eventually to predict in individual patients which combination of drugs would be most effective. :28
Viral infections are unique in their replication characteristics and therefore may escape some drug regimens, so being able to predict up front which drugs are most likely to be effective is critical. I’m Elizabeth Tracey reporting.