PROSTATE CANCER AND OBESITY
ANCHOR LEAD: WHY DO OBESE MEN HAVE MORE ADVANCED PROSTATE CANCER AT DIAGNOSIS? ELIZABETH TRACEY REPORTS
Men who are obese have a multitude of health issues to deal with, among them the likelihood that if they develop prostate cancer it will be more advanced at the time of diagnosis than the same disease in thinner men. Alan Partin, chair of urology at Johns Hopkins and one author of a new study examining this observation, explains why.
PARTIN: Over the last five years we began to notice that obese men presented with more advanced prostate cancer, and in trying to understand why that was, we found out that the PSA test was not as useful in these men. Obese men, quite simply, have a higher blood volume, and the PSA gets diluted, thus we detect it less often, and what we’ve discovered in this large study is that we probably need to correct PSA values in men for how obese they are. :29
Partin and colleagues are hard at work to normalize PSA values to account for differences in body mass index. I’m Elizabeth Tracey reporting.