MARY S. LEFFELL, Ph. D., Diplomate, ABHI, ABMLI
ABSTRACTS
FROM 2000

Cavett J, Bennett T, Sparkman J, Kalve L, Vornsand J, Parlow M, Warden M, Leffell MS, Zachary AA and Hildebrand W:  Reference Strand Conformation Analysis of Untyped HLA Class I Molecules in Two American Indian Populations. European Foundation for Immunogenetics, May, 2000, Granada.

Ratner LE, King K, Zachary AA, Cohen CK, Maley WR, Burdick JF, Markowitz JS, Leffell MS and Montgomery RA:  Successful Abrogation of a Positive Crossmatch with Plasmapheresis and Intravenous Immune Globulin in live Donor Renal Transplantation.  Presented at the American Society of Transplantation, Chicago, IL, May, 2000.

Neu AM, Zachary AA, Leffell MS, Case BW, Furth SL and Fivush BA:  Class I HLA Antibody after Immunization with Influenza Vaccine in Pediatric Renal Transplant Recipients.  Presented at the American Society of Transplantation, Chicago, IL, May, 2000.

Leffell MS, Vogelsang GB, Lucas DP, Delaney NL and Zachary AA:  Association between TGFb Expression and Severe GVHD in Allogeneic BMT.  XVIII International Congress of the Transplantation Society, Rome, August 27- September 1, 2000.

Zachary AA, Ratner LE, Delaney NL, Fivush BA and Leffell MS:  Use of ELISA to Monitor and Characterize Antibody Specific for Donor HLA.  XVIII International Congress of the Transplantation Society, Rome, August 27- September 1, 2000.

Zachary AA, Ratner LE, Lucas DP, Kusel CA and Leffell MS:  Effect of Treatment to Modulate Alloantibody, With and Without Renal Transplantation.  XVIII International Congress of the Transplantation Society, Rome, August 27- September 1, 2000.

Ramie T, Schaefer WJ, Sholander JT, Hart JM, Zachary AA and Leffell MS: Comparison of SSP vs. Serologic Typing of HLA Class I.  Human Immunology, 61:s122, 2000.

Schillinger K, Samaniego M, Racusen LC, Paparounis M, Leffell MS and Zachary AA:  Relevance of DRw52-Specific Antibody in Renal Transplantation.  Human Immunology, 61:s79, 2000.

Newman C, Avergas C, Stacy RAP, Leffell MS and Zachary AA:  Evaluation of Automated DNA Purification by the GenoM™-48.  Human Immunology, 61:s118, 2000.

Berger SA, Hopkins KA, Hart JM, Zachary AA and Leffell MS:  Is Allele Level Typing Necessary for Related Bone Marrow Transplantation?  Human Immunology, 61:s89, 2000.

Leffell MS, Vogelsang GB, Lucas DP, Delaney NL and Zachary AA:  Association of High Expression TGFb Genotypes with Severe GVHD, Veno-occlusive Disease (VOD) and Cytokine Release Syndrome (CR) in Bone Marrow Transplantation (BMT).  Human Immunology, 61:s27, 2000.

Delaney NL, Leffell MS and Zachary AA:  Identification of HLA-B Alleles by Reference Strand- mediated Conformation Analysis.  Human Immunology, 62:s153, 2001.

Leffell MS, Delaney NL, Lucas DP, Newman C and Zachary AA:  TNF, TGF, IL-10, IL-6 and IFN Alleles Among African Americans.  Human Immunology, 62:s174, 2001.

Graziani JA, Woronkowicz M, Sholander JT, Leffell MS and Zachary AA:  The Nature of cII- Specific Antibodies Detected by ELISA.  Human Immunology, 62:s128, 2001.

Berger SA, Scott J, Sholander JT, Zachary AA and Leffell MS:  Multiplexed DRB Typing by Reverse SSO Hybridization with Luminex™ Microspheres.  Human Immunology, 62:s145, 2001.

Leffell MS, Hildebrand WH, Iglehart BA, Cavett JW, Hopkins KA and Zachary AA: Limited Polymorphism of HLA Alleles and Haplotypes Among the Lakota Sioux. Human Immunology, 62:s65, 2001.

Iglehart BA, Berger SA, Schaefer WJ, Zachary AA and Leffell MS:  SBT Confirmation of a New A2 Allele not Detected by Allele Group SSP.  Human Immunology, 62:s47, 2001.

Cavett J, Bennett T, Sparkman J, Sidebottom D, Pruett B, Ceballos A, Leffell M, Zachary A and Hildebrand W:  High Resolution Class I Typing Using Reference Strand Mediated Conformation Analysis (RSCATM).  Human Immunology, 62:s43, 2001.

Schaefer WJ, Lucas DP, Tidey LA, Leffell MS and Zachary AA:  Serologic Characterization of HLA-B*4004 by ELISA.  Human Immunology, 62:s42, 2001.

O'Donnell PV, Luznik L, Jones RJ, Vogelsang GB, Leffell MS, Phelps M, Cowan K, Piantadosi S and Fuchs EJ:  Non-myeloablative Bone Marrow Transplantation (BMT) from HLA-mismatched, Related Donors Using Post-Transplant Cyclophosphamide (CY).  Submitted to American Society of Hematology, August 2001.

Zachary AA, Samaniego-Picota M, Kraus E, Molmenti E, Graziani JA and Leffell MS:  Low Levels of HLA Class II-Specific Antibodies are More Prevalent than Previously Recognized and are Relevant to Renal Transplantation.  Accepted for presentation, American Transplant Congress, Washington DC, May, 2002.

Leffell MS, Fallin MD, Erlich HA, Fernandez-Vina M, Hildebrand WH, Hsu SH, Mack S and Zachary AA:  HLA-A, b, CW, DRB1 and DQB1 Alleles and Haplotypes Among the Alaskan Central Yupik.  Tissue Antigens 59(2):s3.4, p.11, 2002.

Delaney NL, Leffell MS and Zachary AA:  Identification of HLA-A & B Alleles by reference Strand-Mediated Conformation Analysis (RSCA).  Tissue Antigens 59(2):s4.4, p.13, 2002.

Zachary AA, Ratner LE, Montgomery RA, Samaniego-Picota M, Kopchaliiska D and Leffell MS:  Specific down-regulation of antibody to donor HLA induced by treatment with CytoGamŇ and plasmapheresis.  Oral presentation, XIX International Congress of the Transplantation Society, August 26, 2002.

Kopchaliiska D, Leffell MS, Montgomery RA, Samaniego M, Neu A and Zachary AA:  Specific down-regulation of antibody to donor HLA in renal transplantation.  Human Immunology, 63:s30, 2002.

Sholander JT, Graziani JA, Schillinger KP, Zachary AA and Leffell MS:  Luminex technology for tests of HLA-specific antibodies.  Human Immunology, 63:s15, 2002.

Newman CL, Lucas DP, Iglehart BA, Leffell MS and Zachary AA:  Serologic epitopes of HLA-DR8 and HLA-DRw52.  Human Immunology, 63:s25, 2002.

Hart JM, Dane KE, Gall RM, Graziani JA, Kusel CA, Reeb BE, Sholander JT, Schaefer WJ, Leffell MS and Zachary AA: Increasing compliance among patients awaiting cadaver renal transplantation. Human Immunology, 63:s106, 2002.

Montgomery RA, Ratner LE, Samaniego M, Fivush B, Sonnenday C, King K, Zachary AA and Leffell MS: Successful transplantation across HLA or ABO barriers.  Human Immunology, 63:s83, 2002.

Cooper M, Zachary AA, Graziani JA, Montgomery RA and Leffell MSAnti-HLA antibody emergence after non-specific activation of immune system.  American Journal of Transplantation, 3:s803, 2003.

Zachary AA, Lucas DP, Montgomery RA and Leffell MS: Expansion of HLA-specific antibodies following treatment with anti-thymocyte globulin.  American Journal of Transplantation, 3:s1287, 2003.

Chesterton KA, Pretl K, Sholander JT, Leffell MS and Zachary AA: Rapid and reliable detection of HLA-specifc antibodies with the Luminex platform.  Submitted to American Society for Histocompatibility and Immunogenetics, June, 2003.

Pretl K, Chesterton KA, Sholander JT, Leffell MS and Zachary AA: Accurate, rapid characterization of HLA-specific antibody using Luminex technology.  Submitted to American Society for Histocompatibility and Immunogenetics, June, 2003.

Vega RM, Lucas DP, Newman CL, Nordman DS, Leffell MS and Zachary AA: Identification of HLA-DR CREGS and implications for transplantation.  Submitted to American Society for Histocompatibility and  Immunogenetics, June, 2003.

Avergas CU, Newman CL, Hart JM, Leffell MS and Zachary AA: GENO-M6: Nucleic acid purifier - Small footprint, big payoff.  Submitted to American Society for Histocompatibility and Immunogenetics, June, 2003.

Zachary AA, Montgomery RA, Kopchaliiska D, Sonnenday C, Warren D and Leffell MS: Down-regulation of donor-specific antibody - A T cell affair?  Submitted to American Society for Histocompatibility and Immunogenetics, June, 2003.

Cooper M, Zachary AA, Graziani JA, Montgomery RA and Leffell MS: Non-specific activation of the immune system can provoke anti-HLA antibodies.  Submitted to American Society for Histocompatibility and Immunogenetics, June, 2003.

Leffell MS, Kopchaliiska D and Zachary AA: Tracking alloreactive B cells with HLA tetramers.  Submitted to American Society for Histocompatibility and Immunogenetics, June, 2003.

Delaney NL, Lucas DP, Zachary AA, Esquenazi V and Leffell MS: Population differences in cytokine expression alleles.  Submitted to American Society for Histocompatibility and Immunogenetics, June, 2003.

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