Professor of Medicine, Oncology and Pathology
Director of Hematology and Coagulation Laboratory, Department of Pathology
Contact Information:
Office: 410-955-6315
Clinical/Academic Interests:
Hemostasis and platelet disorders
Research Interests:
Dr Kickler’s current clinical research involves the study of pathologic blood clotting in variety of clinical disorders including cancer, paroxysmal nocturnal hemoglobinuria, pregnancy, sickle cell disease and lupus. His research shows that measuring total thrombin potential may be useful in determining the relative risk of thrombosis in different clinical situations and may be useful in developing new treatment strategies to prevent thrombosis. In addition, Dr Kickler directs the coagulation laboratories which are used to evaluate patients seen in the Hematology Clinic and Hemophilia Center.
Education/Training:
1965-1969 BA, University of West Virginia
1969-1973 MD, University of West Virginia
1973-1974 Inter, Medicine, University of Wisconsin Hospital
1974-1976 Residency, Clinical Pathology and Fellow in Pathology, Johns Hopkins University
1976-1978 Fellow, Internal Medicine, Mayo Graduate School of Medicine
1978-1980 Fellow in Hematology, Research Fellow in Immunohematology, University of Rochester, School of Medicine
Academic Positions:
1980-1986 Assistant Professor of Pathology and Medicine
1986-1995 Associate Professor of Pathology, Medicine and Oncology
1995-present Professor of Pathology, Medicine and Oncology
1999-2003 Executive Director of the Eugene and Mary B Meyer Center for Advanced Transfusion Practices and Blood Research
Selected Publications
- Santucci RA, Erlich J, Kickler TS. Measurement of tissue factor expression in whole blood. Hemostasis and Thrombosis. 83:445-455, 2000
- Segal J, Petri M, Kickler TS. Tissue factor in patients with systemic lupus erythematosus: Association with disease activity. J Rheumatology. 27: 2827-2832, 2000
- Segal J, Kasper E, Rohde C, Hruban R. Baldwin WH, Samiengo M, Kickler TS. Platelets as a mediator of cardiac transplant rejection. Transplantation. 72:233-237, 2001.
- Segal J, Petri M, Kickler TS. Decision analysis in lupus anticoagulant testing.American J. Hematology. 70:195-205, 2002
- Brotman D, Segal J, Petty B, Kickler TS. Limitations of D-dimer testing in patients with suspected of venous thromboembolism. American J of Medicine 114:276-282, 2003
- Streiff M, Weir E, Segal J, Kickler TS, Grossman S. ABO blood group is a potent risk factor for venous thromboembolism in patients with malignant gliomas. Cancer. 2004 Apr 15;100(8):1717-23.
- Gluckman TJ, Segal JB, Fredde NL, Saland KE, Jani JT, Walenga JM, Prechel MM, Citro KM, Zidar DA, Fox E, Schulman SP, Kickler TS, Rade JJ. Incidence of antiplatelet factor 4/heparin antibody induction in patients undergoing percutaneouscoronary revascularization. Am J Cadiology 95:744-7, 2005
- Slichter SJ, Davis K, Enright H, Braine H, Gernsheimer T, Kao KJ, Kickler T, Lee E, McFarland J, McCullough J, Rodey G, Schiffer CA, Woodson R. Factors affecting posttransfusion platelet increments, platelet refractoriness, and platelet transfusion intervals in thrombocytopenic patients. Blood 105:4106-14, 2005.
- Ganesh K, Billings Y, K. Sharma, J. Dayhoff, H. M. Fales, T. S. Kickler, and E. G. Nabel. A novel MALDI-TOF mass spectroscopic proteomic technique for serumbiomarker assessment in venous thromboembolism. Circulation 108 (17):560, 2003.
- Williams M, Herr M, Kickler T, Ouyang P. Long-term hormone replacement therapy does not causeincreased platelet activation. Journal of Investigative Medicine 51:S379, 2003.
- Brotman, J. B. Segal, J. T. Jani, B. G. Petty, and T. S. Kickler. D-dimer testing in unselected in patients with suspected venous thromboembolism. American Journal of Medicine 114 (4):276-282, 2003.
