Professor of Medicine, Oncology, and Pathology Contact Information: Clinical/Academic Interests | ![]() |
Research Interests
Dr Kickler’s current clinical research involves the study of pathologic blood clotting in variety of clinical disorders including cancer, paroxysmal nocturnal hemoglobinuria, pregnancy, sickle cell disease and lupus. His research shows that measuring total thrombin potential may be useful in determining the relative risk of thrombosis in different clinical situations and may be useful in developing new treatment strategies to prevent thrombosis. In addition, Dr Kickler directs the coagulation laboratories which are used to evaluate patients seen in the Hematology Clinic and Hemophilia Center.
1965-1969 | University of West Virginia Bachelor of Arts |
1969-1973 | University of West Virginia Doctor of Medicine |
| 1973-1974 | University of Wisconsin Hospital, Intern in Medicine |
1974-1976 | The Johns Hopkins University School of Medicine,Residency in Clinical Pathology, |
1976-1978 | Mayo Graduate School of Medicine,Residency in Internal Medicine, |
1978-1980 | University of Rochester School of Medicine,Fellow in Hematology, |
1974-1976 | The Johns Hopkins University School of Medicine, Fellow in Pathology |
1976-1978 | Mayo Graduate School of Medicine, Fellow |
1978-1980 | University of Rochester School of Medicine, Instructor in Medicine |
1980-1986 | The Johns Hopkins University School of Medicine |
1986-1995 | The Johns Hopkins University School of Medicine |
1995 | Johns Hopkins University School of Medicine |
1999–2003 | Executive Director Eugene and Mary B. Meyer Center for Advanced Transfusion Practices and Blood Research |
Selcted Publications
- Santucci RA, Erlich J, Kickler TS. Measurement of tissue factor expression in whole blood. Hemostasis and Thrombosis. 83:445-455, 2000
- Segal J, Petri M, Kickler TS. Tissue factor in patients with systemic lupus erythematosus: Association with disease activity. J Rheumatology. 27: 2827-2832, 2000
- Segal J, Kasper E, Rohde C, Hruban R. Baldwin WH, Samiengo M, Kickler TS. Platelets as a mediator of cardiac transplant rejection. Transplantation. 72:233-237, 2001.
- Segal J, Petri M, Kickler TS. Decision analysis in lupus anticoagulant testing.American J. Hematology. 70:195-205, 2002
- Brotman D, Segal J, Petty B, Kickler TS. Limitations of D-dimer testing in patients with suspected of venous thromboembolism. American J of Medicine 114:276-282, 2003
- Streiff M, Weir E, Segal J, Kickler TS, Grossman S. ABO blood group is a potent risk factor for venous thromboembolism in patients with malignant gliomas. Cancer. 2004 Apr 15;100(8):1717-23.
- Gluckman TJ, Segal JB, Fredde NL, Saland KE, Jani JT, Walenga JM, Prechel MM, Citro KM, Zidar DA, Fox E, Schulman SP, Kickler TS, Rade JJ. Incidence of antiplatelet factor 4/heparin antibody induction in patients undergoing percutaneouscoronary revascularization. Am J Cadiology 95:744-7, 2005
- Slichter SJ, Davis K, Enright H, Braine H, Gernsheimer T, Kao KJ, Kickler T, Lee E, McFarland J, McCullough J, Rodey G, Schiffer CA, Woodson R. Factors affecting posttransfusion platelet increments, platelet refractoriness, and platelet transfusion intervals in thrombocytopenic patients. Blood 105:4106-14, 2005.
- Ganesh K, Billings Y, K. Sharma, J. Dayhoff, H. M. Fales, T. S. Kickler, and E. G. Nabel. A novel MALDI-TOF mass spectroscopic proteomic technique for serumbiomarker assessment in venous thromboembolism. Circulation 108 (17):560, 2003.
- Williams M, Herr M, Kickler T, Ouyang P. Long-term hormone replacement therapy does not causeincreased platelet activation. Journal of Investigative Medicine 51:S379, 2003.
- Brotman, J. B. Segal, J. T. Jani, B. G. Petty, and T. S. Kickler. D-dimer testing in unselected in patients with suspected venous thromboembolism. American Journal of Medicine 114 (4):276-282, 2003.




