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Hepa Filtration

 

Impact of Different Types of Air Filtration and the Incidence of Nosocomial Aspergillosis in Bone Marrow Transplant Recipients

Study

Type of Air Filtration

Aspergillus Spore
Counts (cfu/m3)

Incidence of Nosocomial Aspergillosis

Rhame et al.

1984 

 

 

Pre-HEPA

Post-HEPA

(2x4 foot HEPA filter in the room)

2.0

0.8

10/66 (15%)

17/202 (8%)

Rhame et al.

1985

Post-HEPA

(addition of HEPA filter in the corridor)

0.14

4/97 (4%)

Opal et al

1986

Portable HEPA filters

inside rooms

outside rooms

 


0.8+ 0.003

1.7  + 0.2
 

        

 
43 cases/yr 

 19 cases/yr (p<0.005)

Sherertz et al

1987

Pre-HEPA

Post-HEPA (LAF)

0.16-0.40

0.009

11/33 (33%)

 0/31 (0%)

Barnes et al

1989

Pre-LAF

Post-LAF

133

0

6/19 (32%)

0/19 (0%)

legend - This reviews the studies that have looked at the impact of air filtration on aspergillus infection rates.

Legend: 

HEPA -

High Efficiency Particulate Air

LAF -

Laminar Air Flow

 
 
 
 
 

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