Elizabeth McNally M.D., Ph.D. is the A.J. Carlson Professor of Medicine and Human Genetics at the University of Chicago where she also directs the University of Chicago Institute for Cardiovascular Research. Dr. McNally studies inherited cardiovascular and neuromuscular diseases. Her expertise in the genetic mechanisms of cardiomyopathies and muscular dystrophies has led to new insight about how heart failure and muscle dysfunction occur. In her work, Dr. McNally has identified a number of genes that are important for cardiac and skeletal muscle membrane stability. Her interest in degenerative disorders that affect cardiac and skeletal muscle has also lead to studies in regenerative medicine to improve heart and muscle function. Current research efforts are directed at:
- Improving genetic diagnosis and risk assessment by understanding the complexity of genetic mutations responsible for heart and muscle myopathies.
- Discovering and implementing preventative therapies for heart and muscle myopathies.
Dr. McNally was born and raised in Chicago. She received her undergraduate degree from Barnard College at Columbia University majoring in Biology and Philosophy. She was awarded M.D. and PhD. degrees from the Albert Einstein College of Medicine where she participated in the NIH sponsored Medical Scientist Training Program. Dr. McNally completed postgraduate training in Internal Medicine and Cardiovascular Medicine at the Brigham and Women’s Hospital and Harvard Medical School. Her postgraduate research was at Children’s Hospital in Boston in the Division of Genetics and the Howard Hughes Medical Institute.
In addition to her research, Dr. McNally is active physician who directs the University of Chicago Cardiovascular Genetics Clinic. This clinic provides counseling and cardiovascular care for patients and families with inherited cardiovascular disorders. She is an also an advocate for research and patients through her work with the Muscular Dystrophy Association and Parent Project Muscular Dystrophy Foundation. Dr. McNally directs the NIH sponsored training program in Cardiovascular Sciences. Dr. McNally served on the NIH Cardiac Contractility and Heart Failure Study Section and the Skeletal Muscle and Exercise Physiology Study Section. She is on the Editorial Boards of the Journal of Clinical Investigation, the Journal of Biological Chemistry, Circulation and Circulation Research. She was president of the American Society for Clinical Investigation 2011-2012, and an active member of the Coalition for Life Science and the Board of Directors of Federation of the American Societies for Experimental Biology (FASEB). She has been recognized as an Established Investigator of the American Heart Association and as a Distinguished Clinical Scientist by the Doris Duke Charitable Foundation.