Men with long-term HIV infections are at higher risk than uninfected men of developing plaque in their coronary arteries, regardless of their other risk factors for coronary artery disease, according to results of a study led by Johns Hopkins researchers. A report on the research appears in the April 1 issue of Annals of Internal Medicine.
In a study that began in a pair of infant siblings with a rare heart defect, Johns Hopkins researchers say they have identified a key molecular switch that regulates heart cell division and normally turns the process off around the time of birth. Their research, they report, could advance efforts to turn the process back on and regenerate heart tissue damaged by heart attacks or disease.
A new study shows that coronary artery calcium (CAC) screening, an assessment tool that is not currently recommended for people considered at low risk, should play a more prominent role in helping determine a person's risk for heart attack and heart disease-related death, as well as the need for angioplasty or bypass surgery. CAC screening provides a direct measure of calcium deposits in heart arteries and is easily obtained on a computed tomography (CT) scan.
Johns Hopkins researchers have developed a more accurate way to calculate low-density lipoprotein (LDL) cholesterol, the so-called "bad" form of blood fat that can lead to hardening of the arteries and increase the risk of heart attack and stroke. If confirmed and adopted by medical laboratories that routinely calculate blood cholesterol for patients, the researchers say their formula would give patients and their doctors a much more accurate assessment of LDL cholesterol.
A new study highlights the importance of exercise and physical fitness among people with stable coronary artery disease. Researchers at the Johns Hopkins University School of Medicine and Henry Ford Hospital found that higher levels of physical fitness lower the risk of having heart attacks and increase survival in those with coronary artery disease, whether or not they have had a procedure to open up their blocked arteries.
A review of dozens of studies on the use of statin medications to prevent heart attacks shows that the commonly prescribed drugs pose no threat to short-term memory, and that they may even protect against dementia when taken for more than one year. The Johns Hopkins researchers who conducted the systematic review say the results should offer more clarity and reassurance to patients and the doctors who prescribe the statin medications.
Johns Hopkins Medicine has teamed up with a local philanthropic foundation to provide automated external defibrillators (AEDs), to 10 Baltimore City middle schools for use, if needed, during sporting events and practices. The portable devices, which are used to shock the heart back into a normal rhythm, can save the life of a student athlete, coach or spectator who collapses during practice or a game due to a heart rhythm disorder that causes sudden cardiac arrest.
Irene Pollin, a passionate health advocate and founder of a national organization devoted to heart disease prevention in women, has made a $10 million gift to the Ciccarone Center for the Prevention of Heart Disease. Her donation also establishes the Kenneth Jay Pollin Professorship in Cardiology and will launch pivotal research on heart disease prevention.
A large, multi-center study led by Johns Hopkins researchers has found a significant link between lifestyle factors and heart health, adding even more evidence in support of regular exercise, eating a Mediterranean-style diet, keeping a normal weight and, most importantly, not smoking.
In what promises to be an eye-opener for many doctors and patients who routinely depend on cholesterol testing, a study led by researchers at the Johns Hopkins University School of Medicine found that the standard formula used for decades to calculate low-density lipoprotein (LDL) cholesterol levels is often inaccurate.
In a study of the impact of weight loss on reversing heart damage from obesity, Johns Hopkins researchers found that poor heart function in young obese mice can be reversed when the animals lose weight from a low-calorie diet.
An abdominal aortic aneurysm - a bulge in the large artery that carries blood away from the heart - can be immediately life-threatening if it grows large enough to rupture.
Researchers have found a genetic variant that doubles the likelihood that people will have calcium deposits on their aortic valve.
Researchers at the Johns Hopkins University School of Medicine and Sanford-Burnham Medical Research Institute in California have created a laboratory-grown cell model of an inherited heart condition known as arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C).
The Johns Hopkins Heart and Vascular Institute will hold the very popular “Heartfest” on Saturday, Jan. 19, 2013.
Research by Johns Hopkins cardiologists suggests that electrocardiograms (ECGs) may have a greater and more profound future role in predicting the risk of death from any cause, not just heart problems.
The Johns Hopkins Cardiac Rehabilitation Program at Green Spring Station has received national certification from the American Association of Cardiovascular and Pulmonary Rehabilitation, a designation that recognizes excellent care and the most advanced practices in cardiac rehabilitation. The certification, which is for three years, followed an intensive process of collecting and analyzing data on a wide range of patient outcomes and demonstrating the program’s adherence to the most current standards and guidelines.
An ultra-fast, 320-detector computed tomography (CT) scanner can accurately sort out which people with chest pain need – or don’t need – an invasive procedure such as cardiac angioplasty or bypass surgery to restore blood flow to the heart, according to an international study. Results of the study, which involved 381 patients at 16 hospitals in eight countries, are scheduled to be presented at the European Society of Cardiology Congress in Munich, Germany, on August 28.
Johns Hopkins researchers have discovered a new drug that may be useful in treating a heart rhythm condition called long QT syndrome. The study was published online on June 28 in the Early Edition of the Proceedings of the National Academy of Sciences.
Johns Hopkins heart specialists will screen young athletes for heart problems that can cause sudden death. The screenings will take place at the National Junior Olympic Track & Field Championships at Morgan State University in Baltimore.
With the 2012 Summer Olympics taking place July 27 to Aug. 12, the competition for athletic supremacy will be high and carry with it high rates of injury among the world's most elite athletes.
A detailed study of heart muscle function in mice has uncovered evidence to explain why exercise is beneficial for heart function in type 2 diabetes. The research team, led by scientists at the Johns Hopkins University School of Medicine, found that greater amounts of fatty acids used by the heart during stressful conditions like exercise can counteract the detrimental effects of excess glucose and improve the diabetic heart’s pumping ability in several ways. The findings also shed light on the complex chain of events that lead to diabetic cardiomyopathy, a form of heart failure that is a life-threatening complication of type 2 diabetes.
It is a cellular component so scarce, some scientists even doubted its existence, and many others gave up searching for its molecular structure. Now a team led by researchers at Johns Hopkins has defined the protein structural composition of mitoKATP, a potassium channel in the mitochondria of the heart and other organs that is known to protect against tissue damage due to a heart attack or stroke. Importantly, the newly found channel strongly improves heart cell survival, demonstrating an essential life-saving role.
Since its founding, The Johns Hopkins Hospital has broken new ground, led the field in medicine and made history in countless ways. Just one of the hospital’s many historic achievements is that it was consecutively ranked #1 in the nation for 21 years out of the 23 in which U.S. News & World Report has held its annual rankings of U.S. hospitals. This year, the hospital is again ranked #1 nationally in five specialties, and it is ranked #2 overall in the nation.
Johns Hopkins researchers have discovered that a single protein molecule may hold the key to turning cardiac stem cells into blood vessels or muscle tissue, a finding that may lead to better ways to treat heart attack patients.
Years of planning, construction and designing every detail of a magnificent, 1.6-million-square-foot hospital building finally came to fruition on May 1 when The Johns Hopkins Hospital officially opened the new facility. A carefully choreographed move of several hundred patients from the original Johns Hopkins Hospital into The Charlotte R. Bloomberg Children’s Center and the Sheikh Zayed Tower took place on April 29 and 30, right before the official opening.
A seminar and workshops on the latest research advances and treatments for a heart condition known as ARVD—one of the leading causes of sudden death among teenagers, young adults and young athletes. More than 200 patients and their family members from 25 states across the U.S. and Canada will attend.
Patients with heart and vascular disease will be cared for in spacious, state-of-the-art private rooms when Johns Hopkins opens its new building to the first patients on April 29. The Johns Hopkins Heart and Vascular Institute occupies a major part of the 1.6 million-square-foot facility, which has 560 all-private patient rooms with private baths and 33 expansive operating rooms.
JWriting the first commentary for a new feature in the Journal of the American Medical Association (JAMA), called Viewpoint, Johns Hopkins cardiologists make the case for why a 55-year-old man with a 10 percent estimated risk of heart attack over the next 10 years should be offered statin medication. They were invited to debate a professor who argues against prescribing statins for "primary" prevention-for those who have not had a cardiovascular event, such as a heart attack-even though they may be considered at "intermediate" risk because of elevated cholesterol or other factors. Readers are then invited to vote on which viewpoint they endorse.
Patients who have non-emergency angioplasty to open blocked heart vessels have no greater risk of death or complications when they have the procedure at hospitals without cardiac surgery backup. That is the conclusion of a national a study to assess the safety and effectiveness of such procedures at community hospitals.
Overweight people who shed pounds, especially belly fat, can improve the function of their blood vessels no matter whether they are on a low-carb or a low-fat diet, according to a study being presented by Johns Hopkins researchers at an American Heart Association scientific meeting in San Diego on March 13 that is focused on cardiovascular disease prevention.
Coronary calcium in heart arteries provides important clues about risk, even among younger and elderly patients and those without traditional risk factors, according to new studies.
A team of Johns Hopkins researchers has uncovered further evidence of the benefits of a balanced diet that replaces white bread and pasta carbohydrates with unsaturated fat from avocados, olive oil and nuts — foods typical of the so-called “Mediterranean diet.”
If your doctor says you have a negative stress test, or that your cholesterol or blood pressure are normal, how assured can you be that you're not likely to have a heart attack in the next seven to 10 years? Assessing traditional risk factors, such as age, high blood pressure, cholesterol, smoking and family history can estimate a person's risk, but the picture is not always clear-cut. Some newer tests can be offered to provide reassurance or guidance about the need for medications or further testing.
Hospitals that do not have cardiac surgery capability can perform nonemergency angioplasty and stent implantation as safely as hospitals that do offer cardiac surgery. That is the finding of the nation’s first large, randomized study to assess whether patients do just as well having nonemergency angioplasty performed at smaller, community hospitals that do not offer cardiac surgery.
Doctors at Johns Hopkins have shown that during an increasingly popular type of breast-reconstruction surgery, they can safely preserve the internal mammary artery, in case it is needed for future cardiac surgery.
Magnetic Resonance Imaging (MRI), an important diagnostic test, has traditionally been off limits to more than 2 million people in the United States who have an implanted pacemaker to regulate heart rhythms or an implanted defibrillator to prevent sudden cardiac death. Now, in a study published in the October 4 issue of Annals of Internal Medicine, cardiologists at Johns Hopkins report that a protocol they developed has proved effective in enabling patients with implanted cardiac devices to safely undergo an MRI scan.
Each year in the United States, more than 200,000 people have a cardiac defibrillator implanted in their chest to deliver a high-voltage shock to prevent sudden cardiac death from a life-threatening arrhythmia. While it’s a necessary and effective preventive therapy, those who’ve experienced a defibrillator shock say it’s painful, and some studies suggest that the shock can damage heart muscle.
Johns Hopkins experts in arrhythmogenic right ventricular dysplasia (ARVD) have defined a set of criteria that could be used to assess a patient’s need for an implanted defibrillator to prevent sudden death. In a study to be published in the September 27 issue of the Journal of the American College of Cardiology that is now online, the researchers report that using those criteria, they were able to separate the patients at high risk for a life-threatening irregular heart rhythm from those with low risk.
Heart specialists at Johns Hopkins have figured out how a widely used pacemaker for heart failure, which makes both sides of the heart beat together to pump effectively, works at the biological level. Their findings, published in the September 14 issue of Science Translational Medicine, may open the door to drugs or genetic therapies that mimic the effect of the pacemaker and to new ways to use pacemakers for a wider range of heart failure patients.
The presence of calcium in coronary arteries is a much better predictor of heart attack and stroke than C-reactive protein among people with normal levels of LDL cholesterol, according to a study of more than 2,000 people led by a Johns Hopkins heart specialist.
Johns Hopkins scientists have launched a pioneering research program to create, for the first time, human platelet cells from stem cells in order to study inherited blood clotting abnormalities ranging from clots that cause heart attacks and stroke to bleeding disorders. The study is funded by a $9 million grant from the National Institutes of Health (NIH) as part of a nationwide initiative to examine how genetic variations cause heart, lung and blood diseases.
Heart experts at Johns Hopkins have begun testing a new device designed to replace blocked aortic valves in patients for whom traditional open-heart surgery is considered too risky, such as elderly patients and those with other serious medical conditions. The testing is part of a nationwide study to evaluate the device, which is deployed in a minimally invasive way. The first two Maryland patients to receive the device had it put in place by Johns Hopkins doctors on July 8, 2011.
Gordon F. Tomaselli, M.D., professor and director of the Division of Cardiology at the Johns Hopkins University School of Medicine, will become president of the American Heart Association (AHA), the nation’s leading voluntary health organization focused on cardiovascular disease and stroke, on July 1.
Overweight and obese people looking to drop some pounds and considering one of the popular low-carbohydrate diets, along with moderate exercise, need not worry that the higher proportion of fat in such a program compared to a low-fat, high-carb diet may harm their arteries, suggests a pair of new studies by heart and vascular researchers at Johns Hopkins.
Coronary computed tomographic (CT) angiography, which can detect plaque buildup in heart vessels, is sometimes used as a screening tool to assess the risk for a heart attack. However, the usefulness of the test on low-risk patients who do not have coronary symptoms, such as chest pain, has been unclear.
Harry C. “Hal” Dietz, III, M.D., the Victor A. McKusick Professor of Genetics and Medicine at the McKusick-Nathans Institute of Genetic Medicine at Johns Hopkins and an investigator of the Howard Hughes Medical Institute is one of 72 new members of the National Academy of Sciences, an honorary society that advises the government on scientific matters.
Older, sicker heart-transplant recipients are significantly more likely to be alive a year after their operations if they have their transplants at hospitals that do a large number of them annually, new Johns Hopkins research suggests. These patients fare less well at low-volume centers, the research shows.
Scientists at Johns Hopkins have shown in laboratory experiments in mice that blocking the action of a signaling protein deep inside the heart’s muscle cells blunts the most serious ill effects of high blood pressure on the heart. These include heart muscle enlargement, scar tissue formation and loss of blood vessel growth.
Johns Hopkins scientists have developed a simplified, cheaper, all-purpose method they say can be used by scientists around the globe to more safely turn blood cells into heart cells. The method is virus-free and produces heart cells that beat with nearly 100 percent efficiency, they claim.
An inexpensive, routine blood test could hold the key to why some patients with congestive heart failure do well after being discharged from the hospital and why others risk relapse, costly readmission or death within a year, new Johns Hopkins research suggests.
A team of heart experts at Johns Hopkins has found that dual lab tests of blood clotting factors accurately predict the patients whose blood vessels, in particular veins implanted to restore blood flow to the heart during coronary artery bypass grafting (CABG), are more likely to fail or become clogged within six months. One test gauges the speed of blood platelet clumping and the other measures the level of a clumping chemical byproduct.
A team of scientists at Johns Hopkins and elsewhere has discovered that a single alteration in the genetic code of about a fourth of African-Americans helps protect them from coronary artery disease, the leading cause of death in Americans of all races.
A study of more than 14,000 men and women whose hearts stopped suddenly suggests that the chances of survival are very high if such cardiac arrests are witnessed in large public venues, including airports, sports arenas or malls. The reasons, researchers say, are that almost four out of five such cases appear to be due to a survivable type of heart rhythm disruption and that big places with lots of people are more likely to have an automated external defibrillator, or AED device, handy, along with those who can apply it as well as CPR.
A study among almost 50,000 people worldwide has identified DNA sequence variations linked with the heart’s electrical rhythm in several surprising regions among 22 locations across the human genome. The variants were found by an international consortium, including Johns Hopkins researchers, and reported Nov. 14 in the Nature Genetics advance online publication.
Duke Cameron, M.D., a long-time Johns Hopkins surgeon, internationally renowned for his work in surgical repair of the heart’s main blood vessel, the aorta, has been named the new cardiac surgeon in charge at The Johns Hopkins Hospital and director of the Division of Cardiac Surgery at the Johns Hopkins University School of Medicine.
Johns Hopkins researchers have discovered how statins, the most commonly prescribed class of medication in the United States, appear to trigger a rare but serious autoimmune muscle disease in a small portion of the 30 million Americans who take the cholesterol-lowering drugs.
Rolling back suggestions from previous studies, a Johns Hopkins study of 950 healthy men and women has shown that taking daily doses of a cholesterol-lowering statin medication to protect coronary arteries and ward off heart attack or stroke may not be needed for everyone.
Heart imaging specialists at Johns Hopkins have shown that a combination of CT scans that measure how much blood is flowing through the heart and the amount of plaque in surrounding arteries are just as good as tests that are less safe, more complex and more time-consuming to detect coronary artery disease and its severity.
In remarks prepared for the American Heart Association’s golden anniversary celebration of CPR, a Johns Hopkins cardiologist who learned the life-saving technique as a medical student 46 years ago from one of CPR’s pioneers suggests the future of the technique is as bright as its past.
Low levels of vitamin D, the essential nutrient obtained from milk, fortified cereals and exposure to sunlight, doubles the risk of stroke in whites, but not in blacks, according to a new report by researchers at Johns Hopkins.
Some 30 Johns Hopkins cardiologists, nurses, technical staff and administrative volunteers have for the first time partnered with Baltimore City Public Schools to screen for early signs of heart disease in as many as 2,000 high-school-bound Baltimore-area students.
A new study suggests yet another reason for Americans to abandon their current fatty diets in favor of one rich in fruits and vegetables and low in saturated fat. Choosing these healthier options appears to significantly reduce the long-term risk of heart disease in patients with mildly elevated blood pressure, particularly African Americans.
Once more — and for the 20th year in a row — The Johns Hopkins Hospital has taken the top spot in U.S. News & World Report’s annual rankings of American hospitals, placing first in five medical specialties and in the top five in 10 others.
In what is believed to be the largest review of the human genetic code to determine why some people's blood platelets are more likely to clump faster than others, scientists at Johns Hopkins and in Boston have found a septet of overactive genes, which they say likely control that bodily function.
Transplant surgeons at Johns Hopkins who have reviewed the medical records of more than 20,000 heart transplant patients say that it is not simply racial differences, but rather flaws in the health care system, along with type of insurance and education levels, in addition to biological factors, that are likely the causes of disproportionately worse outcomes after heart transplantation in African Americans.
A consortium of five Baltimore hospitals, led by the Johns Hopkins Department of Emergency Medicine, has acquired and donated to Baltimore city new wireless technology able to transmit electrocardiograms from the field over the Internet to hospital-based medical specialists.
Johns Hopkins cardiac surgeons — none who are involved in the care of ABC ‘s Barbara Walters — are prepared to give background to reporters or comment on diseased aortic valves and aortic valve replacement surgery, performed at a rate of more than one a week at Johns Hopkins for many years.
Nicholas J. Fortuin, M.D., one of Johns Hopkins Medicine's most dedicated and admired clinical cardiologists, teachers and institutional leaders, died unexpectedly near Owings Mills Sunday while biking, his favorite sport and pastime. The cause of death was not known, but it is likely he suffered a heart attack, colleagues say.
A protein discovered in fruit fly eyes has brought a Johns Hopkins team closer to understanding how the human heart and other organs automatically "right size" themselves, a piece of information that may hold clues to controlling cancer.
The Johns Hopkins University School of Medicine has been awarded a $9.7 million federal grant to study ways to improve cardiovascular outcomes among African-American patients and to understand and reduce racial and ethnic disparities in blood pressure management in Baltimore.
Cardiologists and heart imaging specialists at 15 medical centers in eight countries, and led by researchers at Johns Hopkins, have enrolled the first dozen patients in a year-long investigation to learn whether the subtle squeezing of blood flow through the inner layers of the heart is better than traditional SPECT nuclear imaging tests and other diagnostic radiology procedures for accurately tracking the earliest signs of coronary artery clogs.
To this day, it still shocks former Dunbar High School basketball coach Bob Wade when he thinks back to June 1993, when he first heard that his star former student, 27-year-old Reggie Lewis, 6'7" and 195 pounds, the top scorer and center for the Boston Celtics, had suddenly collapsed and died during basketball shoot-around.
A team of Johns Hopkins and other researchers have found in animal experiments that an antidepressant developed over 40 years ago can blunt and even reverse the muscle enlargement and weakened pumping function associated with heart failure.
Healthy, older adults free of heart disease need not fear that bouts of rapid, irregular heartbeats brought on by vigorous exercise might increase short- or long-term risk of dying or having a heart attack, according to a report by heart experts at Johns Hopkins and the U.S. National Institute on Aging (NIA).
Heart experts at Johns Hopkins are calling premature the early halt of a study by researchers at Walter Reed Army Medical Center and Washington Hospital Center on the benefits of combining extended-release niacin, a B vitamin, with cholesterol-lowering statin medications to prevent blood vessel narrowing. Cardiovascular atherosclerosis, as it is also known, is believed responsible for one in three deaths in the United States each year.
A team of U.S., Canadian and Italian scientists led by researchers at Johns Hopkins report evidence from studies in animals and humans supporting a link between Alzheimer’s disease and chronic heart failure, two of the 10 leading causes of death in the United States.
To best detect early signs of life-threatening heart defects in young athletes, screening programs should include both popular diagnostic tests, not just one of them, according to new research from heart experts at Johns Hopkins.
Researchers at Johns Hopkins are reporting what is believed to be the first conclusive evidence in men that the long-term ill effects of vitamin D deficiency are amplified by lower levels of the key sex hormone estrogen, but not testosterone
For the second year in a row, volunteer heart disease experts from Johns Hopkins will staff and run Maryland’s only screening program to detect early signs of life-threatening heart abnormalities, including hypertrophic cardiomyopathies, in student athletes.
Denton A. Cooley, M.D., an American pioneer in heart surgery, will be the guest speaker at the Johns Hopkins University School of Medicine’s 114th convocation on Friday, May 22, 2009 at 10:30 a.m. at the Joseph Meyerhoff Symphony Hall in Baltimore.
Researchers at the Johns Hopkins University School of Medicine, along with an international team of collaborators, have identified common genetic changes associated with blood pressure and hypertension. The study, reporting online next week in Nature Genetics, breaks new ground in understanding blood pressure regulation and may lead to advances in hypertension therapy.
MAY 2-5, BALTIMORE CONVENTION CENTER, 1 PRATT ST.
- BLACK KIDS WITH HIGH BLOOD PRESSURE MAY BE AT HIGHER RISK FOR HEART DISEASE
- MEMO TO DOCS: MINIMIZE SCANS THAT EXPOSE YOUNG PATIENTS TO RADIATION WHEN POSSIBLE
- FLU SHOTS A MUST FOR KIDS WITH SICKLE CELL DISEASE
- TEEN PARENTS OF CRITICALLY ILL NEWBORNS DON’T GET SEVERITY OF ILLNESS
- HIV TREATMENT LAGGING BEHIND FOR MANY INFECTED YOUTH
Researchers at the Johns Hopkins University School of Medicine have found that a chemical commonly used in the production of such medical plastic devices as intravenous (IV) bags and catheters can impair heart function in rats.
Lung experts from Johns Hopkins and elsewhere are calling on physicians to suspend the routine use of potent heartburn medications in asthmatics solely to temper recurrent attacks of wheezing, coughing and breathlessness.
Physician-science investigator Edward Kasper, M.D., an expert in chronic heart failure and the heart transplantation that often results from the disease, has been named the new clinical director of the Johns Hopkins University School of Medicine’s Division of Cardiology and co-director of the School’s Heart and Vascular Institute.
One minute, he’s a strapping 40-year-old with an enviable cholesterol level, working out on his treadmill. The next, he’s dead.
Millions more patients could benefit from taking statins, drugs typically used to prevent heart attacks and strokes, than current prescribing guidelines suggest, Johns Hopkins doctors report in a new study.
Two of the world’s leading experts in cardiac surgery will be in Pavia, Italy, tomorrow to attend the signing ceremony of a three-year collaboration agreement between Johns Hopkins Medicine International and San Matteo Hospital.
A widely heralded Johns Hopkins safety initiative to reduce bloodstream infections in intensive care units (ICUs) was implemented in 30 states starting Feb. 1 and could save an estimated $3 billion dollars and 30,000 lives annually. In addition, the program has been launched in Spain and will begin in the United Kingdom starting in April. Pilot programs are also under discussion with health care leaders in Peru and Chile.
Johns Hopkins and other researchers report what is believed to be the first direct evidence in lab animals that the erectile dysfunction drug sildenafil amplifies the effects of a heart-protective protein.
Johns Hopkins researchers have discovered that a drop in blood potassium levels caused by diuretics commonly prescribed for high blood pressure could be the reason why people on those drugs are at risk for developing type 2 diabetes. The drugs helpfully accelerate loss of fluids, but also deplete important chemicals, including potassium, so that those who take them are generally advised to eat bananas and other potassium-rich foods to counteract the effect.
Heart experts at Johns Hopkins have evidence that life-saving coronary angioplasty at community hospitals is safer when physicians and hospital staff have more experience with the procedure.
Taking a cue from the way drugs like Viagra put the biological brakes on a key enzyme involved in heart failure, scientists at Johns Hopkins have mapped out a key chemical step involved in blocking the enzyme.
Naturally produced sex hormones may influence the risk and progression of atherosclerosis, or hardening of the arteries, Johns Hopkins researchers report in a recent study. The findings may help explain the increased risk men have of developing heart disease, which runs about twofold higher than women’s heart disease risk worldwide.
Outstanding researchers in cardiovascular medicine will be honored in The Johns Hopkins Hospital Houck Lobby at 4 p.m., Wednesday, Nov.5, as part of the Johns Hopkins Heart and Vascular Institute’s annual awards ceremony named to commemorate the late Hopkins physician Stanley L. Blumenthal, B.A. ’39 and M.D. ’43.
In a 10-year study of more than a thousand kidney failure patients, sudden cardiac death emerged as the number one cause of death for patients on dialysis, according to a Johns Hopkins researcher. The study, already published online and appearing in the Nov. 2 issue of Kidney International, identified systemic inflammatory response and malnutrition as key risk factors for the fatal heart attacks.
A heart expert at Johns Hopkins is calling for all women with a waistline measuring more than 35 inches to get an annual check-up and detailed risk assessment for heart problems because excess abdominal fat, even in the mildly obese and overweight, leads more than a third of women to underestimate their lifetime risk of having a heart attack, stroke or chest pain (angina.)
The state Medical Examiner's Office cited cardiac arrhythmia, or abnormal heart rhythm, as the cause of sudden death of 19 year-old U.S. Naval Academy student Kristen Dickmann.