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Heart & Vascular Institute

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Clinical Research Programs

Last updated: January 2012

  • Frailty Study –Impact of frailty on outcomes in elderly (>65 yrs) cardiac surgical patients
  • Thoratec HeartMate II LVAS Pivotal Study – multicenter study of ventricular assist devices for destination therapy patients
  • COCAD Study – longitudinal study of cognitive outcomes in patient with coronary artery disease
  • Stroke database study – review of brain MRI’s in patients with stroke after cardiac surgery
  • Aortic Valve Operative Outcomes in Marfan syndrome patients
  • Hypoperfusion and stroke after CABG surgery
  • Monitoring of Cerebral Blood Flow Autoregulation using Near Infrared Spectroscopy
  • GeneTICS – MSSA Swabs
  • National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC)
  • Evaluation of the HeartWare LVAD System for the treatment of advanced heart failure
  • Prospective Randomized On-X Valve Anticoagulation Clinical Trial (PROACT)
  • Cardiac Structural & Functional Assessments using Three-Dimensional Transesophageal Echocardiographic Imaging
  • Continuous Cerebral Autoregulation Monitoring to reduce brain injury from cardiac surgery
  • MRI of cerebrovascular reactivity using induced hypercapnia and its relationship with mild cognitive decline (RespirAct)
  • Red Cell Storage Duration in Cardiac Surgery Patients (RECESS)
  • A Prospective, Randomized, Controlled, Unblinded, Multi-Center Clinical Trial to Evaluate the HeartWare® Ventricular Assist System for Destination Therapy of Advanced Heart Failure
  • Medtronic CoreValve U.S. Pivotal Trial (High risk surgical patients)
  • Serum Biomarkers to Predict Brain Injury Study
  • Benefits of Post-Pyloric Feeding Tubes in Critically Ill Patients
  • AV Pacing Wire Study
  • Neuropsychiatric Outcomes After Heart Surgery (NOAHS)
  • The EXCEL trial: Abbott Vascular EXCEL Clinical Trial: Evaluation of Xience Prime or Xience V versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization
  • Genetic Determinants of Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
  • Prospective Analysis of an Intraoperative Urine Flow, Biomarker Profiles and Impact on Clinical Outcomes
  • Congenital Heart Surgeon Society Database (CHSS)
  • Society of Thoracic Surgeons (STS) Adult Cardiac Surgery Database participant
  • Society of Thoracic Surgeons (STS) Congenital Heart Surgery Database participant
  • INTERMAC’s Mechanical Circulatory Assist Device Registry