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Clinical Research Programs

Last updated: July 2016

  • National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC)
  • GeneTICS – MSSA Swabs
  •  Congenital Heart Surgeons’ Society (CHSS) Studies in Congenital Heart Disease
  •  Retrospective Review of Outcomes following Cardiac Surgical Procedures at Johns Hopkins Hospital and Washington University
  • Application of Behavioral Survey for Standardization of Clinical Practice in Cardiac Surgery
  • Clinical Outcomes Associated with Temporary Epicardial Pacing after Cardiac Surgery
  • Tolerance of Early Extubation in Cardiac Surgery
  • Nutrition Support Management in Cardiac Surgery
  • Correlation of Transfusion and Postoperative Infection in the STS Registry
  • Correlation of Postoperative Bleeding and Platelet Count
  • Predicting Readmissions in Cardiac Surgery
  • Prediction Model for Unplanned Cardiac Surgery Intensive Care Unit (CSICU) Readmissions
  • Retrospective Analysis of Patients on Mechanical Circulatory Support Devices
  • Red Cell Storage Duration Study in Cardiac Surgery (RECESS)
  • Biomarkers of readmission and mortality – determining if circulating biomarker levels measured in existing pre and post blood samples predict 30-day readmission and/or mortality in children with congenital heart disease.
  • Pharmacokinetics of Vancomycin in Pediatric Patients Post-operative from Cardiac Surgery
  • Evaluation of Warfarin Therapy after the Fontan Procedure at a Large Children’s Center
  • Retrospective review evaluating associations between nadir oxygen delivery (DO2) during pediatric cardiac surgery and a biomarker of brain injury to determine a new approach of goal directed perfusion to protect brain injury during CPB.
  • Comparative efficacy of iNO and inhaled epoprostenol in the perioperative management of pulmonary arterial hypertension in pediatric patients following cardiac surgery.
  • Implementing Phase Of Care Mortality Analysis (POCMA) for a Pediatric Cardiothoracic Surgical Population
  • ECHSA (European Congenital Heart Surgeons Association) Supravalvular Aortic Stenosis Database
  • Shear stress, cell trajectories, thrombosis and damage to blood in left ventricular assist devices
  • Nanofiber Tissue Engineered Vascular Graft Using 3D Printing Technology
  • Nanofiber tissue engineered vascular grafts for complex shapes using 3D printing technology
  • Patient-specific nanofiber tissue engineered vascular graft (TEVG) to enhance the available treatments for children suffering from congenital heart disease (CHD)
  • Creation of Human Cardiac Muscle from Induced Pluripotent Stem Cell using Bio-3D printer
  • Novel Device for the Treatment of Heart Failure: Peristaltic Pump Created from Human Induced Pluripotent Stem Cell using Bio-3D printer
  • Clinical Registries:
    • Society of Thoracic Surgeons (STS) Adult Cardiac Surgery Database
    • Society of Thoracic Surgeons (STS) Congenital Heart Surgery Database
    • INTERMACS - Interagency Registry for Mechanically Assisted Circulatory Support
    • PEDIMACS – Pediatric Registry for Mechanical Assisted Circulatory Support
    • Extracorporeal Life Support Organization (ELSO) Registry
    • Pediatric Cardiac Critical Care Consortium (PC4)
  • An easily calculable and highly predictive risk index for postoperative renal failure after heart transplantation
  • The efficacy and safety of epidural-based analgesia in a case series of patients undergoing lung transplantation
  • A risk score to predict renal failure in adult patients following lung transplantation
  • Preoperative performance status impacts perioperative morbidity and mortality after lung transplantation
  • The survival benefit of simultaneous heart-kidney transplantation extends beyond dialysis-dependent patients
  • Extracorporeal membrane oxygenation for profound cardiogenic shock due to cocaine toxicity
  • Utilization of AngioVac and snare for eradication of a mobile right atrial thrombus
  • Iliac vein to right atrium bypass in a patient with a prior vena cava ligation for invasive renal cell carcinoma
  • Prolonged ischemia is not associated with primary graft failure and does not impact survival following lung transplantation
  • Trends, clinical outcomes, and cost implications of mitral valve repair versus replacement concomitant with aortic valve replacement
  • A novel risk score to predict dysphagia following cardiac surgery procedures
  • Continuous intraoperative cefazolin infusion may reduce surgical site infections during cardiac surgical procedures: a propensity-matched analysis