Aortic Valve Operative Outcomes in Marfan Patients

Summary of Trial:	The purpose of this protocol is to evaluate and compare operative outcomes of the aortic valve-sparing (AVS) and aortic valve replacement (AVR) surgical interventions in different categories of patients with Marfan syndrome and estimate the predictors of the surgical outcomes.
Principal Investigator:	Dr. Luca A. Vricella
Study Coordinator:	Kimberly Behrens, RN, BSN Email: kbehren1@jhmi.edu (410) 502-1914
Study Long Title:	Aortic Valve Operative Outcomes in Marfan Patients
Study Short Title:	N/A
JHU IRB Number:	04-10-15-03
Funding Source:	National Marfan Foundation, USA
Inclusions:	Has a confirmed diagnosis of Marfan syndrome Adult and pediatric patients under the age of 65 with Marfan syndrome Needs to undergo aortic valve operation as confirmed by operating surgeon
Exclusions:	Unable to sign consent form
Clinical Trial Site:	Johns Hopkins Hospital 600 North Wolfe Street, Blalock 618 Baltimore, MD 21287-4618 This is a multi-center study – there are 20 additional sites across the U.S. and internationally that are participating in this clinical trial.
Start Date:	2005
Anticipated End Date:	2009
Compensation for Participating:	None