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Comparative Effectiveness Research

Comparative effectiveness research is research aimed evaluating and comparing the implications and outcomes of two or more health care strategies to address a particular medical condition. The goal of comparative effectiveness research is to generate better information about the risks and benefits and costs of different treatment options in order to provide health-care decision makers—including patients, clinicians, purchasers, and policymakers—with up-to-date, evidence-based information about their treatment options to make informed health care decisions. 

In the Division of General Internal Medicine, investigators design and conduct comparative effectiveness studies in diverse fields including in diabetes, obesity, and depression management. Several of the active projects are funded by the DEcIDE Network of the Agency for Healthcare Research and Quality. Since 2005, this Network has funded practical studies about the outcomes, comparative clinical effectiveness, safety, and appropriateness of health care items and services.

Information about the faculty working in this research area and their projects is provided below.
       
Eric Bass, MD, MPH
Professor of Medicine and Health Policy and Management
Director,
 Johns Hopkins Evidence-Based Practice Center
Co-Director, Johns Hopkins DeCIDE Center 

Research Interests: Evidence-based medicine methods
To see publication abstracts: PubMed

Wendy Bennett, MD, MPH
Assistant Professor of Medicine and Population, Family and Reproductive Health
Research Interests: Women's health, diabetes and obesity
To see publication abstracts: PubMed

Jeanne M. Clark, MD, MPH, FACP
Frederick Brancati, MD Professor of Medicine 
Joint Appointment in  Epidemiology
Director, Division of General Internal Medicine
Core Faculty, Welch Center for Prevention, Epidemiology, and Clinical Research
Research Interests: Epidemiology of obesity, fatty liver disease, and related conditions, epidemiology and effectiveness of bariatric surgery
To see publication abstracts: PubMed 

Lisa Cooper, MD, MPH, FACP
Professor of Medicine, Epidemiology, and Health, Behavior and Society
Core Faculty, Welch Center for Prevention, Epidemiology, and Clinical Research
Director, Center to Eliminate Cardiovascular Health Disparities
Research Interests: Health disparities in depression care; spirituality; physician-patient relationship and communication
To see publication abstracts: PubMed

Gail Daumit, MD, MHS
Associate Professor of Medicine, Psychiatry and Behavioral Sciences, Epidemiology, and Health Policy and Management
Core Faculty,Welch Center for Prevention, Epidemiology, and Clinical Research
Research Interests: Epidemiology and prevention of obesity, diabetes, and cardiovascular disease in adults with severe mental illness
To see publication abstracts: PubMed

Nisa Maruthur, MD, MHS
Assistant Professor of Medicine
Co-Director, GIM Fellowship Program
Research interests: Individualized medicine for the prevention and treatment of type 2 diabetes and obesity, pharmacogenomics of type 2 diabetes, comparative effectiveness
To see publication abstracts: PubMed

Karen A. Robinson, PhD, MSc
Associate Professor of Medicine, Epidemiology and Health Policy and Management
Co-Director, Evidence-Based Practice Center, JHSPH
Research and professional interests: Evidence-based health care, health informatics
To see publication abstracts: PubMed

Jodi Segal, MD, MPH
Associate Professor of Medicine
Research Interests: Evidence-based medicine methods
To see publication abstracts: PubMed

Sean Tunis, MD, MSC
Director, Center for Medical Technology Policy, Baltimore, MD
Research interests: Stake-holder engagement, study design
To see publication abstracts: PubMed

Albert Wu, MD, MPH
Professor of Medicine, Surgery and Health Policy and Management
Joint appointments in Epidemiology, and  International Health  
Director, Center for Health Services and Outcomes Research 
Research Interests: Patient safety, comparative effectiveness research, patient-reported outcomes, quality of care, HIV       
To see publication abstracts: PubMed
 

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