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Hypertension Research

High blood pressure affects 65 million Americans. Another 59 million Americans have prehypertension, which increases their chances of developing cardiovascular disease. People over 55 have a 90 percent chance of developing high blood pressure in their lifetime. High blood pressure is a major risk factor for 3 of the 10 leading causes of death in the United States: heart disease (#1), stroke (#3), and kidney disease (#9) (source: National Center for Health Statistics). As the United States population becomes older—and increasingly overweight and obese—high blood pressure will become an even bigger problem. Hypertension imposes an especially heavy burden on the health of African Americans. Hypertension can be prevented by lifestyle modification, including weight loss and salt reduction, but the achievement of these goals in primary care has been disappointing. At Johns Hopkins, GIM faculty are engaged in the investigation and treatment of hypertension across the full range of its natural history.

Information about the faculty working in this research area and their projects is provided below.

Lawrence Appel, MD, MPH
Professor of Medicine, Epidemiology, and International Health
Welch Center for Prevention, Epidemiology, and Clinical Research
Research Interests: Prevention of blood pressure-related cardiovascular and kidney diseases through pharmacologic and non-pharmacologic approaches, often nutrition-based       
To see publication abstracts: PUBMED   

Lisa Cooper, MD, MPH, FACP
Professor of Medicine, Epidemiology, and Health, Behavior and Society
Core Faculty, Welch Center for Prevention, Epidemiology, and Clinical Research

Director, Center to Eliminate Cardiovascular Health Disparities
Research Interests: Hypertension, health disparities, physician-patient relationship and communication
To see publication abstracts: PUBMED

Michael Klag, MD, MPH
Professor of Epidemiology, Health Policy and Management, and Medicine
Dean, Johns Hopkins Bloomburg School of Public Health
Research Interests: High blood pressure as a risk factor for CKD and ESRD
To see publication abstracts: PUBMED

Edgar (Pete) Miller, MD, PhD
Professor of Medicine and Epidemiology
Core Faculty,
Welch Center for Prevention, Epidemiology, and Clinical Research
Research Interests: Trials of lifestyle change to reduce blood pressure
To see publication abstracts: PUBMED

Dhananjay (Jay) Vaidya, MBBS, PhD, MPH   
Associate Professor of Medicine  
Research Interests: Statistics, vascular properties, gender differences and hormonal influences, randomized clinical trials  
To see publication abstracts: PUBMED

J. Hunter Young, MD, MHS
Associate Professor of Medicine and Epidemiology
Core Faculty,
Welch Center for Prevention, Epidemiology, and Clinical Research
Research Interests: Genetic epidemiology, novel risk factors for CVD, hypertension, and
insulin resistance
To see publication abstracts: PUBMED

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