Academic Appointment(s)
- Assistant Professor -Departments of Medicine, Biostatistics, and Epidemiology Center on Aging and Health
Research Interests:
- My major research interests focus on multisystem physiologic risk factors and associated threshold relationships for the development of frailty in older adults. Other areas of interests include developing tools for medical decision making that are more relevant and appropriate for geriatric population, and translation of research findings into improved design of interventions, in terms of choice, timing, and duration of intervention, to lead to compression of morbidity. Current research activities include characterization of trajectories of change in biomarkers over time; determining the effect of competing mortality on the association between physiologic dysregulations and the development of frailty.
Clinical Interests:
- N/A
Selected publications:
- Xue Q-L, Bandeen-Roche K, Zhou J, Varadhan R, Fried LP. Initial manifestations of frailty criteria and the development of frailty phenotype in the Women’s Health and Aging Study II. J Gerontol A Biol Sci Med Sci. in press.
- Xue Q-L, Fried LP, Glass TA, Laffan AM, Chaves PHM. Life-Space Constriction, Development of Frailty, and the Competing Risk of Mortality: The Women’s Health and Aging Study I. Am J Epidemiol. 2008; 167(2):240-48.
- Cappola AR, Xue Q-L, Walston JD, Leng SX, Ferrucci L, Guralnik J, Fried LP, DHEAS Levels and Mortality in Disabled Older Women: The Women's Health and Aging Study I. J Gerontol A Biol Sci Med Sci. 2006;61(9):957-62.
- Bandeen-Roche, K, Xue, Q-L, Ferrucci, L, Walston, J, Guralnik, JM, Fried, LP, Phenotype of Frailty: characterization in the Women’s Health and Aging Studies. J Gerontol A Biol Sci Med Sci. 2006; 61(3):262-6.
- Xue, Q-L, Bandeen-Roche, K, Combining complete multivariate outcomes with incomplete covariate information: a latent class approach. Biometrics. 2002; 58: 66-76.
Education/Training:
- Ph.D.: The Johns Hopkins University, Baltimore, Maryland
- M.S.: Humboldt State University, Arcata, California
- B.S.: Shanghai Fisheries University, Shanghai, China
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