Paulo H. M. Chaves, M.D., Ph.D.

Academic Appointment(s)

• Assistant Professor
• Joint Appointment, Department of Epidemiology, School of Public Health

Division Title(s):

• Core Faculty, Center on Aging and Health, Johns Hopkins University, Baltimore, MD, USA

Research Interests:

• Frailty, physical disability, clinical and subclinical cardiovascular disease, anemia, sarcopenia, autonomic dysfunction, executive cognitive function, fatigue, and epidemiology of aging

Clinical Interests:

• General Geriatrics

Selected publications:  

• Fried LP, Bandeen-Roche K, Chaves PHM, Johnson B. Preclinical disability predicts incident mobility disability in older women. J Gerontol Med Sci 2000; 55A: M43-M52
• Chaves PHM, Garrett ES, Fried LP. Predicting the risk of mobility disability in older women with screening nomograms: The Women’s Health and Aging Study II. Arch Intern Med 2000; 160:2525-2533
• Chaves PHM, Volpato S, Fried LP. Challenging the World Health organization criteria for anemia in older women. 2001 Annual Scientific Meeting American Geriatrics Society, Chicago, IL, November 9-13, 2001. J Am Geriatr Soc Vol 49 2001:S3.
• Chaves PHM, Ashar B, Guralnik JM, Fried LP. Looking at the relationship between hemoglobin concentration and prevalent mobility difficulty in older women. Should the criteria currently used to define anemia in older people be
• Chaves PHM, Carlson MC, Fried LP. Cognitive function in high functioning older women: does hemoglobin concentration matter? J Am Geriatr Soc 2002 Jul;50(4):S-149.
• Chaves PHM, Mody SH, Najib MM, Siegartel LR, Blasi MV, Woodman RC. Anemia in the Elderly is Associated With Increased Healthcare Costs and Resource Utilization. 45^th American Society of Hematology Annual Meeting, December 2003. Blood 2003; 102(11):750a-751a.
• Chaves PHM, Mody SH, Najib MM, Siegartel LR, Hill K, Woodman RC.  Clinical epidemiology of anemia in older adults. Blood, December 6-9, 2003.
• Chaves PHM, Woodman R, Fried Linda P. Relation between hemoglobin concentration and frailty status in older adults: the Women’s Health and Aging Studies I and II. 45^th American Society of Hematology Annual Meeting, December 2003.
  Blood 2003; 102(11):751a.
• Chaves PHM, Xue QL, Fried LP. Relationship between Serum Erythropoietin and Hemoglobin Concentration in Community-Dwelling Older Women. The Women’s Health and Aging Studies I and II. 45^th American Society of Hematology Annual Meeting, December 2003. Blood 2003; 102(11):509a.
• Chaves PHM, Kuller LH, O’Leary DH, Manolio TA, Newman AB. Subclinical Cardiovascular Disease in Older Adults: Insights from the Cardiovascular Health Study American Journal of Geriatric Cardiology, 2004;13(3):137-51
• Chaves PHM, Xue Q-L, Guralnik JM, Volpato S, Ferrucci L, Fried LP. What does constitute normal hemoglobin concentration in community-dwelling disable older women? J Am Geriatr Soc 2004 Nov;52(11):1811-6
• Fujiwara Y, Chaves PHM, Takahashi R, Amano H, Kumagai S, Fujita K, Yoshida H, Wang DG, Varadhan R, Uchida H, Shinkai S.  Relationships between arterial pulse wave velocity and conventional Atherosclerotic risk factors in community-dwelling people. Preventive Medicine 2004 Dec;39(6):1135-42
• Fujiwara Y, Chaves PHM, Takahashi R, Amano H, Yoshida H, Kumagai S, Fujita K, Wang DG, Shinkai S.  Arterial pulse wave velocity as a marker of poor cognitive function in an elderly community-living population. J Gerontol A Biol Sci Med Sci. 2005 May;60(5):607-12.
• Frisoli A Jr, Chaves PHM, Pinheiro MM, Szejnfeld VL. The effect of nandrolone decanoate on bone mineral density, muscle mass, and hemoglobin levels in elderly women with osteoporosis: a double-blind, randomized, placebo-controlled clinical trial. J Gerontol A Biol Sci Med Sci. 2005 May;60(5):648-53.
• Chaves PHM, Semba RD, Leng S, Woodman RC, Ferrucci L, Guralnik JM, Fried LP. Impact of anemia and cardiovascular disease on frailty status of community-dwelling older women: The Women’s Health and Aging Studies I and II. J Gerontol A Biol Sci Med Sci. 2005 Jun;60(6):729-35 (with accompanying Editorial)
• Chaves PHM, Carlson M, Ferrucci L, Guralnik JM, Semba R, Fried LP.  Association of Mild Anemia with Executive Function Impairment in Community-dwelling Older Women: The Women’s Health and Aging Study II. J Am Geriatr Soc. 2006 Sep;54(9):1429-35.
•  Shinkai S, Chaves PHM, Fujiwara Y, Watanabe S, Shibata H, Yoshida H, Suzuki T. Beta₂-Microglobulin for Risk Stratification of Total Mortality in the Elderly: Comparison to Cystatin C and C-reactive Protein. Archives of Internal Medicine, in press.
• Stein PK, Barzilay JI, Chaves PHM, Traber J, Domitrovich PP, Heckbert SR, Gottdiener JS. Higher Levels Of Inflammation Factor And Greater Insulin Resistance Are Independently Associated With Higher Heart Rate And Lower Heart Rate Variability In Normoglycemic Older Individuals: The Cardiovascular Health Study. J Am Geriatr Soc., in press

 Education/Training:

• M.D.:  Rio de Janeiro Federal University (UFRJ) School of Medicine (Rio de Janeiro, Brazil)
• Ph.D.: Johns Hopkins University School of Hygiene and Public Health
• Internal Medicine Residency:  Pedro Ernesto University Hospital (HUPE), Rio de Janeiro State University (UERJ) (Rio de Janeiro, RJ, Brazil).     

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