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Amy M. Matteini, PhD

Academic Appointment(s)

Research Associate
Division of Geriatric Medicine and Gerontology
Johns Hopkins University School of Medicine

Research Interests:

  • Genetic epidemiology of age-related syndromes and conditions
  • Endophenotype development for genetic association analysis
  • Genetics of muscle strength in older adults
  • Intersection of nutrition and genetics in older populations

Selected Publications:

Matteini AM, Walston JD, Fallin MD, Bandeen-Roche K, Kao WHL, Allen RH, Guralnik J, Fried LP, Stabler SP, Markers of functional B-vitamin deficiency and the association with frailty syndrome in older women. J Nutr Health Aging. 2008 May;12(5):303-8.

Matteini AM, Walston JD, Bandeen-Roche K, Arking DE, Allen RH, Guralnik J, Fried LP, Chakravarti A, Stabler SP, Fallin MD, Genetic factors of one-carbon transfer and association with serum homocysteine and frailty syndrome in older women. J Nutr Health Aging, 2010;Jan;14(1): 73-7.

Tanaka T, Roy CN, Yao W, Matteini A, Semba RD, Arking D, Walston JD, Fried LP, Singleton A, Guralnik J, Abecasis GR, Bandinelli S, Longo DL, Ferrucci L, A genome-wide association analysis of serum iron concentrations. Blood. 2010 Jan 7;115(1):94-6.

Walston JD, Matteini AM, Nievergelt C, Lange LA, Fallin MD, Barzilai N, Ziv E, Pawlikowska L, Kwok P, Cummings SR, Kooperberg C, LaCroix A, Tracy RP, Atzmon G, Lange EM, Reiner AP, Inflammation and stress-related candidate genes, plasma interleukin-6 levels and longevity in older adults, Exp Gerontol. 2009 May;44(5):350-5.

Ferrucci L, Perry J, Matteini AM, Perola A, Tanaka T, Silander K, Rice N, Melzer D, Murray A, Cluett C, Fried LP, Albanes D, Corsi A, Cherubini A, Guralnik J, Bandenelli S, Singleton A, Virtamo J, Walston J, Semba RD, Frayling TM, Common variation in the beta-carotene 15,15’-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study, Amer J of Hum Genet, 2009; Feb; 84(2): 123-33. 

Moore AZ, Biggs ML, Matteini A, O'Connor A, McGuire S, Beamer BA, Fallin MD, Fried LP, Walston J, Chakravarti A, Arking DE, Polymorphisms in the mitochondrial DNA control region and frailty in older adults.  PLoS One. 2010 Jun 10;5(6):e11069.

Spencer ME, Jain A, Matteini A, Beamer BA, Wang NY, Leng SX, Punjabi NM, Walston JD, Fedarko NS, Serum levels of the immune activation marker neopterin change with age and gender and are modified by race, BMI, and percentage of body fat. J Gerontol A Biol Sci Med Sci. 2010 Aug;65(8):858-65.

Matteini AM, Fallin MD, Kammerer CM, Schupf N, Yashin AI, Christensen K, Arbeev KG, Barr RG, Mayeux, R, Newman AB, Walston JD, Heritability Estimates of Endophenotypes of Long and Health Life: the Long Life Family Study, J Gerontol A Biol Sci Med Sci, 2010, Sept 2, Epub.


ScM: Johns Hopkins Bloomberg School of Public Health, Epidemiology, 2002

Ph.D.: Johns Hopkins Bloomberg School of Public Health, Epidemiology, 2007

Post-doctoral Fellowship: Johns Hopkins University School of Medicine, Division of Geriatric Medicine and Gerontology, 2007-2010.

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