Karin Blakemore, MD

Education:

BA, University of Pennsylvania, 1975
M.D., Medical College of Ohio at Toledo, 1978
Resident in Obstetrics and Gynecology, New York University Medical Center, 1982
Fellow in Human Genetics, Yale University School of Medicine, 1985
Fellow in Maternal-Fetal Medicine, Washington University School of Medicine, 1987

Main Interests:

Research interests relate to genetic abnormalities of the fetus and include cytogenetic mosaicism in the placenta and the relevance of cytogenetic abnormalities to clinical diagnosis and embryonic development, with Dr. Gail Stetten, as well as studies related to normal and abnormal fetal growth and development, and advances using antepartum diagnostic imaging modalities, intrapartum maternal and fetal physiology and processes, and red cell and platelet alloimmunization. Experience with in utero fetal treatment and first trimester prenatal diagnosis led to a new area of research, in utero bone marrow transplantation for genetic disorders of the fetus. Using an animal model, our primary aim is to determine the critical factors which allow or disallow engraftment in the early fetus Clinical and educational interests: prenatal diagnosis, normal and high risk pregnancy; alloimmunization, obstetrical sonography, maternal or fetal genetic disorders, and labor.
 
Research Interests:

• Prenatal diagnosis and genetic abnormalities of the fetus
• Intrapartum maternal and fetal physiology
• Fetal therapy
• In utero bone marrow transplantation
• Red cell alloimmunization and platelet alloimmunization 

Clinical Activities:

• Board Certification: American Board of Medical Genetics; American Board of Obstetrics and Gynecology (ABOG); Maternal-Fetal Medicine, ABOG
• Clinical Interests: Fetal diagnosis and treatment; obstetrical sonography; high risk obstetrics; intrapartum maternal-fetal physiology; management of hematologic disorders in the fetus
• Clinics:
  
  Obstetrical Practice @ Green Spring Johns Hopkins at Green Spring Station
  10755 Falls Road
  Suite 420
  Lutherville, MD
  Phone: 410-583-2749 Fax: 410-583-2756
    
  Obstetrical Sonography Johns Hopkins Hospital
  600 N. Wolfe Street
  Blalock 2
  Baltimore, MD 21287
  Phone: 410-955-8976
    
  Prenatal Diagnostic Center
  Phone: 410-955-30

Educational Activities

• Fellowship Director, Maternal-Fetal Medicine
• Year II Medical Student Curriculum in Reproductive Endocrinology, The Johns Hopkins University School of Medicine: “Prenatal Diagnosis.”
• Co-Course Director, OB/GYN Ultrasound Course (Tri-State), sponsored by Johns Hopkins University School of Medicine
• Preceptor, first year medical students, Introduction to Clinical Medicine and American Medical Women's Association
• Preceptor, Clinical Aspects of Public Health Problems in the Mother and Newborn, Population and Family Health Sciences, Johns Hopkins University School of Hygiene and Public Health 

 Recognition and Leadership Roles:

• Member, Board of Directors, The Society for Maternal-Fetal Medicine
• Member, Maternal-Fetal Medicine Network Units Advisory Board, National Institute of Child Health and Human Development
• Member, Working Group 3 - Discussion of Ethical, Legal and Social Issues, Prenatal Gene Transfer: Scientific, Medical and Ethical Issues, The Third Gene Therapy Policy Conference, National Institutes of Health
• Member, Committee on Ethics, The American College of Obstetricians and Gynecologists
• Editorial Board Member, Fetal Diagnosis and Therapy 
• Editorial Board Member, Journal of Maternal-Fetal and Neonatal Medicine

Honors and Awards:

• 1999-2001: Best Doctors in Baltimore, Baltimore on Line: Top Doctors
• 2002:  The Acclaimed Educator Award, Department of Gynecology and Obstetrics, The Johns Hopkins University School of Medicine, Presented by the Residency Graduating Class of 2002
• 2003:  National Institutes of Health Distinction “Changing the Face of Medicine: Celebrating America’s Women Physicians,” displayed at the National Library of Medicine at the National Institutes of Health Bethesda, Maryland: displayed in the digital portrait gallery on the National Institutes of Health website. 

Funded Awards:

• 9/1/03 – 12/31/05 
  NIH-NIAID - 1 RO1 AI555683-01
     “A Canine Model for In Utero Bone Marrow Transplantation”
     Award: $583,333 (PI: Karin J. Blakemore)

Selected Publications:

Althaus J, Blakemore KJ. Fetomaternal alloimmune thrombocytopenia: the questions that still remain. J
Matern-Fetal Neonatal Med 2007;20:633-7.

Aina-Mumuney AJ, Blakemore K, Fischer A. Recommendations for antenatal surveillance in fetal
gastroschisis. J Reprod Med 2007;52:577-8.

Aina-Mumuney A, Althaus JE, Henderson JL, Blakemore KJ, Johnson EA, Graham EM. Can electronic
fetal monitoring identify the fetus with histologic chorioamnionitis and funisitis a risk factor for neonatal brain
injury? J Repro Med 2007;52:762-8.

Aina-Mumuney AJ, Holcroft CJ, Blakemore KJ, Bienstock JL, Hueppchen NA, Milio LA, Crino JP.
Intrahepatic veins for fetal blood sampling: One center’s experience. Am J Obstet Gynecol Am J Obstet
Gynecol 2008;198:387-388.

Wood E, Dowey S, Saul D, Cain C, Rossiter J, Blakemore K, Stetten G. Prenatal diagnosis of mosaic
trisomy 8q studied by ultrasound, cytogenetics, and array-CGH. Am J Med Genet 2008;Part A 146A:764-
769.

Aina-Mumuney A, Wood ED, Corson VL, Stetten G, Jari S, Boehm CD, Blakemore KJ. Clinical
consequences of an increasing trend of preferential use of cultured villi for molecular diagnosis by CVS.
Pren Diagn 2008;28:332-4.

Holcroft CJ, Blakemore KJ. Gurewitsch ED, Driggers RW, Northington FJ, Fischer AC. Large fetal
sacrococcygeal teratomas: could early delivery improve outcome? Fetal Diag & Ther 2008;24:55-60.

Cain CC, Saul DO, Oehler E, Blakemore K, Stetten G. Prenatal detection of a subtle unbalanced
chromosome rearrangement by karyotyping, FISH and array comparative genomic hybridization. Fetal
Diagn Ther 2008;24:286-290.

Contact Information:

Karin Blakemore, MD

The Johns Hopkins Hospital
Dept. of Gynecology & Obstetrics
Phipps Building, Room 228
Baltimore, MD 21287-1228
Phone: (410) 955-6207
Fax: (410) 614-8305
E-Mail: dwheele@jhmi.edu