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Genetics Resources Core Facility

The Johns Hopkins Genetic Resources Core Facility (CORE)

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The Genetic Resources Core Facility is a JHU service center including the Core Store and five Research Services.  Collectively, these components offer a wide variety of products and services to all Hopkins researchers. The components of the GRCF include:

Core Store provides one-stop shopping for more than 100,000 products from 16 of the leading life science companies.  In addition to its product offering the store charges no shipping and handling fees and has free delivery to three campuses; East Baltimore, Bayview and Homewood. There is also, convenient 24/7 access to several hundred products via the Core Store 24/7 at these locations; Blalock 1026, CRB II LB-06 and the Asthma and Allergy Building 1st floor. For more information go to www.jhucorestore.com

Cell Center facilitates basic scientific research by providing expertise and service in all mammalian cell culture. For more information go to http://cellcenter.grcf.jhmi.edu

DNA Analysis Facility provides on-site same day or next day Sanger-based sequencing, low cost Oligonucleotide synthesis through a partnership with Sigma-Genosys, access to a self service Applied Biosystems 7900 machine for Real-time PCR applications, and easy ordering of siRNAs, miRNAs and qPCR primers from QIAGEN. For more information please go to http://daf.jhmi.edu

Fragment Analysis Facility provides genomic DNA isolation, low through-put genotyping including SNP, STR and VNTR analysis, cell line authentication, mycoplasma testing, whole genome amplification, and DNA storage for research purposes. For more information go to http://faf.grcf.jhmi.edu

High Throughput Sequencing features an Illumina Genetic Analyzer II, which has the capability to generate sequences with high accuracy at an extremely low cost per base.  Using highly parallel sequencing-by-synthesis chemistry, billions of bases are produced with each run at a cost of less than 1% of capillary based methods.  Free project consultation is available.  For more information go to http://grcf.jhmi.edu/hts

SNP Center provides high through-put genotyping services using both the Illumina BeadArrayTM technology and the Affymetrix 6.0 genotyping chip to both the JHU and larger scientific communities.  The lab has the capacity to produce millions of genotypes on hundreds of samples each week.  No cost access to the SNP Center can be obtained through our CIDR (cidr.jhmi.edu) or RSnG (rsng.nhlbi.nih.gov) contracts.  For more information go to http://snpcenter.grcf.jhmi.edu


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