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Katherine Bruner: Michael A. Shanoff Award
I believe a project is only as good as the people working on it, and I am very thankful to have had a wonderful team of scientists work with me on this project.
Mentor: Robert Siliciano
My work consisted of a comprehensive genetic profiling of latent HIV-1 present in individuals who were on antiretroviral therapy for different lengths of time. We discovered that the vast majority of all viruses in these individuals are defective and therefore do not pose a barrier to HIV-1 cure. We also discovered that current methods used to measure the amount of latent virus in individuals on HIV antiretroviral therapy do not accurately measure the amount of intact, replication-competent virus in a patient, revealing a need to develop better methods for measuring HIV-1.
Why did you choose Johns Hopkins for your work?
Johns Hopkins is extremely well known for excellence in biomedical research, making it a clear favorite during my graduate school decision process. From its reputation and my own research, I knew that Johns Hopkins would provide me with the knowledge and resources to pursue great science that was both interesting and impactful.
What does receiving this award mean to you?
I am very honored and humbled to receive this award. This work was a truly collaborative effort, and it could not have been done without the many colleagues and collaborators who contributed.
What contributed to your project's success?
I believe a project is only as good as the people working on it, and I am very thankful to have had a wonderful team of scientists work with me on this project. The Siliciano lab is a tight-knit group, and the guidance, advice and support from all of the lab members was critical to the success of this work.
What thoughts do you have about Young Investigator's Day itself?
Students and fellows play a critical role in all academic research, and the Young Investigators’ Day is a unique opportunity to specifically highlight this fact.
What are your plans over the next year or so?
I look forward to continuing my work in the Siliciano lab as a postdoctoral fellow.
What are your hobbies or interests?
I enjoy tap and ballet dancing and sometimes dance around the lab when no one is around.