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DRC Pilot and Feasibility Program

The Pilot and Feasibility (P and F) Program, directed by Dr. Sally Radovick, of the JHU-UMD Diabetes Research Center (DRC) is seeking applications to support new initiatives in diabetes-related biomedical, epidemiological or behavioral research. The JHU-UMD DRC is an NIH-funded joint-venture between the Johns Hopkins University, University of Maryland and Howard University School of Medicine. It is composed of Cores that are designed to support research in diabetes and related endocrine and metabolic diseases. The JHU-UMD DRC is one of seven national centers.

Monetary awards funded by the P and F program provide limited support to the development of preliminary data sufficient for the funding of a research grant application, or to the testing of an innovative hypothesis which might have important implications or yield significant results for diabetes-related research.


Faculty members at the Johns Hopkins University, University of Maryland or Howard University who are:

  1. New investigators without current or past NIH support as principal investigators, OR
  2. Established grant supported investigators who have not previously worked in diabetes-related areas OR
  3. Established investigators in diabetes-related areas with a proposal for testing the feasibility of a new or innovative idea that is both diabetes-related and represents a clear and distinct departure from his/her ongoing research interests.

Applications for collaborative projects are strongly encouraged.

Awarding Mechanism

After receiving the submissions, the P and F Steering Committee will review the applications for compliance with administrative guidelines. The proposals will then be sent to two reviewers, generally from outside the institutions, for peer review.We plan to award up to 4 applications this year depending on the number of fundable applications and the availability of funds.

Submission Requirements

  1. Pilot and Feasibility (P and F) Submission Form (available for download on the DRC website)
  2. NIH PHS 398 Form Page 2: Summary, Relevance, Project/Performance Sites, Senior/Key Personnel, Other Significant Contributors, and Human Embryonic Stem Cells.
  3. NIH PHS 398 Form Page 4: Detailed Budget for Initial Budget Period (4/1/2015-3/31/2016) *
  4. NIH PHS 398 Form Page 5: Budget for Entire Proposed Project Period (Includes Budget Justification)*
  5. Biographical Sketch in NIH PHS 398 format.
  6. Research Plan on NIH PHS 398 Continuation Pages (see section PHS 398: Part 5.5 of PHS 398 Instructions for details; follow all instructions). Please limit your research plan to 3,000 words, not including references.
  7. A Brief Candidate Background Description, limited to 350 words, on NIH PHS 398 Continuation Page.

*The proposed budget for each award may be up to $50,000 year in direct costs (no indirect costs). One year of funding will be awarded. A second year of funding will be possible if productivity is demonstrated in a progress report to the Steering Committee.

Pilot and Feasibility (P and F) Submission Form is available for download on the DRC website below.

Application Submission

Please submit your application via email by 5 p.m. on Friday, February 6, 2015 as one PDF file to: Cheikh Seye.

Awards will be presented during the 2015 Annual JHU-UMD Diabetes Research Center Symposium, April 16, 2015.


Cheikh Seye
The Johns Hopkins University School of Medicine, Department of Pediatrics
Divisions of Endocrinology and Metabolism

Phone: 410-955-6182
Fax: 410-502-7580

Previous Awardees


Circulating MicroRNAs as Potential Biomarkers of Type 2 Diabetes in African American Adults
Kanwal Gambhir, Ph.D., Howard University

Type-1 Interferon in Immunoregulation and Development of Diabetes
Giorgio Raimondi, Ph.D., Johns Hopkins University

Role of NADPH Oxidase 4 and Mitochondrial Dysfunction in Maternal Diabetes-induced Heart Defects
Peixin Yang, Ph.D., University of Maryland


Control of hypothalamic neurogenesis by dietary and hormonal signals
Seth Blackshaw Ph.D., Johns Hopkins University

Role of Lipolysis in Intermittent-Hypoxia Induced Insulin Resistance
Kamal Moudgil Ph.D., University of Maryland

The Role of Cardiovascular DIsease Risk in Memory and Alzheimer's diseaseRole of Lipolysis in Intermittent-Hypoxia Induced Insulin Resistance
Thomas O. Obisesan M.D., Howard University

Cellular senescence in cystic fibrosis-related diabetes
Scott Blackman M.D., Johns Hopkins University


Role of Lipolysis in Intermittent-Hypoxia Induced Insulin Resistance
Jonathan Jun M.D., Johns Hopkins University

Identifying Signaling Pathways Involved in the Differentiation of Human Embryonic Stem Cells to Insulin Producing Cells
Michael Parsons, Ph.D., Johns Hopkins

mHealth Activity Behavior Intervention for Older Adults with Diabetes
Charlene Quinn, Ph.D., University of Maryland


The Role of Co‐Activator p300 in Regulating Hepatic Gluconeogenesis
Ling He, M.D., Ph.D., Johns Hopkins University

Estrogens Regulate Endocrine Influences of Adipose Tissue on Skeletal Muscle
Espen E. Spangenburg, Ph.D., University of Maryland

The Role of Adipocyte ACOT7 in Diabetic Dyslipidemia
Michael J. Wolfgang, Ph.D, Johns Hopkins University


The Origin, Metabolism, and Pathology of Ovarian Glucose
Charles Chaffin, Ph.D., University of Maryland

Hyperandrogenism and Polycystic Ovarian Syndrome in the Old Order Amish
Sara DiVall, M.D., Johns Hopkins University; Patrick McArdle, Ph.D., University of Maryland

Influences of Prenatal Nutrition, Genetics, Childhood Growth Trajectory, Sexual Maturation, and their Interactions on
Metabolic Outcomes during Puberty: A Twin Study

Youfa Wang, M.D., M.S., Ph.D., Johns Hopkins University


Formative Research for a Prepared Food Source Intervention to Reduce Diabetes Risk Among Urban African Americans
Joel Gittelsohn, Ph.D., Johns Hopkins University

Pilot Study on the Use of OmniPod Subcutaneous Insulin Delivery Pump in Hospitalized Patients
Kristi D. Silver, M.D., University of Maryland

Characterizing the Metabolic Function of a Novel Adipokine, CTRP12
Guang William Wong, Ph.D.


Examining the Relationship Between Stress, Dietary Lapse and Weight Regain Among Weight-Reduced Adults with Type 2 Diabetes
Lawrence J. Cheskin, M.D., Johns Hopkins University

Promoting Islet Transplants by Targeting Fas Ligand
Abdel Hamad, D.V.M., Ph.D., Johns Hopkins University

Post-Translational Regulation of Glucokinase by Glucagon-like Peptide 1 (GLP1)
Mark A. Rizzo, Ph.D., University of Maryland