Title(s):
Assistant Professor of Pediatrics
Director of Epigenetic and Chromatin Clinic
Assistant Program Director, Clinical Genetics
Assistant Professor of Pediatrics and Genetics
Assistant Program Director, Clinical Genetics
Assistant Professor of Pediatrics and Genetics
Appointment Phone:
Primary Location:
The Johns Hopkins Hospital
Expertise:
Clinical Genetics, General Pediatrics
Education and Experience
Training
- University of Iceland (Reykjavik )/ (2001)
Residencies
- The Johns Hopkins Hospital (Baltimore MD)/ Pediatrics (2012)
Certifications
- Pediatrics, American Board of Pediatrics (2011)
Locations
The Johns Hopkins Hospital
600 N. Wolfe Street
Hospital Main Entrance - Sheikh Zayed Tower
Baltimore, MD 21287
Phone: 410-955-3071
Location Map
The Johns Hopkins Hospital
600 N. Wolfe Street
Hospital Main Entrance - Sheikh Zayed Tower
Baltimore, MD 21287
Phone: 410-955-3071
Location Map
Department / Division
- Pediatrics
Centers/Institutes
Centers / Institutes
- McKusick-Nathans Institute for Genetic Medicine
Bio
Physician Title
Director of Epigenetic and Chromatin Clinic
Assistant Program Director, Clinical Genetics
Assistant Professor of Pediatrics and Genetics
Assistant Program Director, Clinical Genetics
Assistant Professor of Pediatrics and Genetics
Awards and Honors
Fulbright Fellowship (2002)
Thor Thors Award, American-Scandinavian Foundation (2006)
Margaret Ellen Nielsen Fellow Award, IGM (2007)
Francis F. Schwentker Award, Department of Pediatrics (2009)
Frank L. Coulson, Jr. Award for Clinical Excellence (2012)
Thor Thors Award, American-Scandinavian Foundation (2006)
Margaret Ellen Nielsen Fellow Award, IGM (2007)
Francis F. Schwentker Award, Department of Pediatrics (2009)
Frank L. Coulson, Jr. Award for Clinical Excellence (2012)
Expertise
- Clinical Genetics
- General Pediatrics
Research
Research and Publications
Bjornsson HT, Fallin MD, Feinberg AP. An integrated epigenetic and genetic approach to common human disease. Trends Genet. 2004 Aug;20(8):350-8. PMID: 15262407 [PubMed -indexed for MEDLINE]
Bjornsson HT, Ellingsen LM, Jonsson JJ. Transposon-derived repeats in the human genome and 5-methylcytosine-associated mutations in adjacent genes. Gene. 2006 Mar 29;370:43-50. Epub 2006 Jan 30. PMID: 16446059 [PubMed - indexed for MEDLINE]
Bjornsson HT, Brown LJ, Fallin MD, Rongione MA, Bibikova M, Wickham E, Fan JB, Feinberg AP. Epigenetic specificity of loss of imprinting of the IGF2 gene in Wilms tumors. J Natl Cancer Inst. 2007 Aug 15;99(16):1270-3. Epub 2007 Aug 8. PMID: 17686827 [PubMed - indexed for MEDLINE]
Bjornsson HT, Albert TJ, Ladd-Acosta CM, Green RD, Rongione MA, Middle CM, Irizarry RA, Broman KW, Feinberg AP. SNP-specific array-based allele-specific expression analysis. Genome Res. 2008 May;18(5):771-9. Epub 2008 Mar 27. PMID: 18369178 [PubMed - indexed for MEDLINE]
Bjornsson HT, Sigurdsson MI, Fallin MD, Irizarry RA, Aspelund T, Cui H, Yu W, Rongione MA, Ekstrm TJ, Harris TB, Launer LJ, Eiriksdottir G, Leppert MF, Sapienza C, Gudnason V, Feinberg AP. Intra-individual change over time in DNA methylation with familial clustering. JAMA. 2008 Jun 25;299(24):2877-83. PMID: 18577732 [PubMed - indexed for MEDLINE]
Wen B, Wu H, Bjornsson H, Green RD, Irizarry R, Feinberg AP. Overlapping euchromatin/heterochromatin- associated marks are enriched in imprinted gene regions and predict allele-specific modification. Genome Res. 2008 Nov;18(11):1806-13. Epub 2008 Oct 10. PMID: 18849526 [PubMed - in process]
Sigurdsson MI, Smith AV, Bjornsson HT, Jonsson JJ. HapMap methylation-associated SNPs, markers of germline DNA methylation, positively correlate with regional levels of human meiotic recombination. Genome Res. 2009 Feb 20. PMID: 19158364
Sigurdsson MI, Smith AV, Bjornsson HT*, Jonsson JJ*. The distribution of a germline methylation marker suggests a regional mechanism of LINE-1 silencing by the piRNA-PIWI system. BMC Genet. 2012 Apr 24;13:31. PubMed PMID: 22530917. *Co-corresponding authors.
Bjornsson HT, Ellingsen LM, Jonsson JJ. Transposon-derived repeats in the human genome and 5-methylcytosine-associated mutations in adjacent genes. Gene. 2006 Mar 29;370:43-50. Epub 2006 Jan 30. PMID: 16446059 [PubMed - indexed for MEDLINE]
Bjornsson HT, Brown LJ, Fallin MD, Rongione MA, Bibikova M, Wickham E, Fan JB, Feinberg AP. Epigenetic specificity of loss of imprinting of the IGF2 gene in Wilms tumors. J Natl Cancer Inst. 2007 Aug 15;99(16):1270-3. Epub 2007 Aug 8. PMID: 17686827 [PubMed - indexed for MEDLINE]
Bjornsson HT, Albert TJ, Ladd-Acosta CM, Green RD, Rongione MA, Middle CM, Irizarry RA, Broman KW, Feinberg AP. SNP-specific array-based allele-specific expression analysis. Genome Res. 2008 May;18(5):771-9. Epub 2008 Mar 27. PMID: 18369178 [PubMed - indexed for MEDLINE]
Bjornsson HT, Sigurdsson MI, Fallin MD, Irizarry RA, Aspelund T, Cui H, Yu W, Rongione MA, Ekstrm TJ, Harris TB, Launer LJ, Eiriksdottir G, Leppert MF, Sapienza C, Gudnason V, Feinberg AP. Intra-individual change over time in DNA methylation with familial clustering. JAMA. 2008 Jun 25;299(24):2877-83. PMID: 18577732 [PubMed - indexed for MEDLINE]
Wen B, Wu H, Bjornsson H, Green RD, Irizarry R, Feinberg AP. Overlapping euchromatin/heterochromatin- associated marks are enriched in imprinted gene regions and predict allele-specific modification. Genome Res. 2008 Nov;18(11):1806-13. Epub 2008 Oct 10. PMID: 18849526 [PubMed - in process]
Sigurdsson MI, Smith AV, Bjornsson HT, Jonsson JJ. HapMap methylation-associated SNPs, markers of germline DNA methylation, positively correlate with regional levels of human meiotic recombination. Genome Res. 2009 Feb 20. PMID: 19158364
Sigurdsson MI, Smith AV, Bjornsson HT*, Jonsson JJ*. The distribution of a germline methylation marker suggests a regional mechanism of LINE-1 silencing by the piRNA-PIWI system. BMC Genet. 2012 Apr 24;13:31. PubMed PMID: 22530917. *Co-corresponding authors.
Research Interests
- Rubinstein-Taybi syndrome
- Kabuki syndrome
- Epigenetics
- Mendelian Disorders of the Histone Machinery
More Info
Languages
- English
- German
- Danish
- Icelandic
Memberships
American Academy of Pediatrics
American Society of Human Genetics
American Society of Human Genetics
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