
Title(s):
Assistant Professor of Surgery
Assistant Professor of Surgery
Cardiac Surgeon
Cardiac Surgeon
Appointment Phone:
410-955-2800
Primary Location:
The Johns Hopkins Hospital
Expertise:
Aneurysms, Aortic Aneurysms, Aortic Surgery, Arrhythmia, Atrial Fibrillation, Atrial Septal Defects, Cardiac Surgery, Cardiovascular Surgery, Congenital Heart Disease - Adult, Coronary Artery Bypass Graft Surgery, Coronary Artery Disease, Coronary Bypass Surgery, Heart Bypass, Heart Disease, Heart Failure, Heart Transplant, Irregular Heartbeat, Maze Procedure, Minimally Invasive Aortic Valve Replacement, Minimally Invasive Cardiac Surgery, Minimally Invasive Interventions, Minimally Invasive Mitral Valve Repair, Minimally Invasive Thoracic Surgery, Mitral Stenosis, Mitral Valve Repair, Radiofrequency Ablation for Atrial Fibrillation, Thoracic Aortic Aneurysms, Valvular Disease, Valvular Heart Disease, Valvular Heart Surgery
Education and Experience
Training
- All India Institute of Medical Sciences (New Delhi )/ (1996)
Residencies
- The Johns Hopkins Hospital (Baltimore MD)/ Cardiothoracic Surgery (2011)
Fellowships
- St George's Hospital Medical School (London SW17 ORE )/ Cardiothoracic Surgery (2008)
Locations
The Johns Hopkins Hospital
600 N. Wolfe Street
Sheikh Zayed Tower Room Suite 7107
Baltimore, MD 21287
Phone: 410-955-2800
Appointment Phone: 410-955-2800
Location Map
Department / Division
-
Surgery - Cardiac Surgery
Centers/Institutes
Centers / Institutes
- Atrial Fibrillation Center
- Heart and Vascular Institute
Bio
Biography
Kaushik Mandal, M.D., is an Assistant Professor of Surgery at The Johns Hopkins Hospitals Heart and Vascular Institute. He has been the Chief Resident of Cardiac Surgery, as well as the Chief Resident of Thoracic Surgery at The Johns Hopkins Hospital. In addition to his time at The Johns Hopkins Hospital, Dr. Mandal completed residencies at Guys & St Thomas, St Marys and St. Georges Hospitals in London, UK and All India Institute of Medical Sciences in New Delhi, India. Dr. Mandal received the deans scholarship from the Johns Hopkins Bloomberg School of Public Health and an honorary fellowship from the European Society of Cardiology for his outstanding clinical research. He has been a member and a fellow of the Royal College of Surgeons in Edinburg and received the Professor V. Ramalingaswami Best Intern Award at the All India Institute of Medial Sciences in New Delhi, India. Kaushik Mandal, M.D., specializes in cardiac surgery especially minimally invasive and robotic cardiac surgery, including mitral valve repairs, tricuspid valve repairs, ASD closures, maze procedures for atrial fibrillation, Aortic valve and aneurysm repairs, off pump and coneventional coronary artery bypass, heart failure surgery, heart transplant, valvular heart disease, and many other cardiac conditions. His current research focus is in the field of Robotics and Advanced imaging in cardiac surgery. He has been published in Circulation, the publication of the American Heart Association; The Journal of Cardiovascular Electrophysiology, The Annals of Thoracic Surgery, and many other industry journals and is frequently invited speaker to various scientific meetings.
Physician Title
Assistant Professor of Surgery
Cardiac Surgeon
Cardiac Surgeon
Awards and Honors
1988 - National Scholar, National Council of Educational Research and Training, New Delhi, India
1995 - Professor V Ramalingaswami Best Intern Award, All India Institute of Medical Sciences, New Delhi, India
2001 - Member of the Royal College of Surgeons of Edinburgh, General Surgery
2007 - Fellow of the Royal College of Surgeons of Edinburgh, Cardiothoracic Surgery
2007 - Awarded Honorary Fellowship of the European Society of Cardiology in Recognition of academic achievements
2011 - Deans Scholarship, Johns Hopkins Bloomberg School of Public Health
1995 - Professor V Ramalingaswami Best Intern Award, All India Institute of Medical Sciences, New Delhi, India
2001 - Member of the Royal College of Surgeons of Edinburgh, General Surgery
2007 - Fellow of the Royal College of Surgeons of Edinburgh, Cardiothoracic Surgery
2007 - Awarded Honorary Fellowship of the European Society of Cardiology in Recognition of academic achievements
2011 - Deans Scholarship, Johns Hopkins Bloomberg School of Public Health
Expertise
- Aneurysms
- Aortic Aneurysms
- Aortic Surgery
- Arrhythmia
- Atrial Fibrillation
- Atrial Septal Defects
- Cardiac Surgery
- Cardiovascular Surgery
- Congenital Heart Disease - Adult
- Coronary Artery Bypass Graft Surgery
- Coronary Artery Disease
- Coronary Bypass Surgery
- Heart Bypass
- Heart Disease
- Heart Failure
- Heart Transplant
- Irregular Heartbeat
- Maze Procedure
- Minimally Invasive Aortic Valve Replacement
- Minimally Invasive Cardiac Surgery
- Minimally Invasive Interventions
- Minimally Invasive Mitral Valve Repair
- Minimally Invasive Thoracic Surgery
- Mitral Stenosis
- Mitral Valve Repair
- Radiofrequency Ablation for Atrial Fibrillation
- Thoracic Aortic Aneurysms
- Valvular Disease
- Valvular Heart Disease
- Valvular Heart Surgery
Professional Highlights
2007-2008 Administrative Specialist Registrar in Cardiothoracic Surgery, St Georges Hospital, London, UK
July 2009 - Dec 2009 Chief Resident in Thoracic Surgery, Johns Hopkins Hospital, Baltimore, USA
2010-2011 Chief Resident in Cardiac Surgery, Johns Hopkins Hospital, Baltimore, USA
July 2009 - Dec 2009 Chief Resident in Thoracic Surgery, Johns Hopkins Hospital, Baltimore, USA
2010-2011 Chief Resident in Cardiac Surgery, Johns Hopkins Hospital, Baltimore, USA
Research
Research and Publications
JOURNAL ARTICLES
Kumar A, Seenu V, Mohan N, Kaul A, Bhalla A, Batra R, Mandal K, Aggarwal S, Initial experience with day case laparoscopic cholecystectomy in a tertiary care hospital in India. National Medical Journal of India. 1999; 12(3):103-107
Mandal K, West C, The management of immediate post-traumatic seizures in children following minor head injury- time for a multicentre study? Childs Nervous System. 2001; 17(11): 670-673
Mandal K, Jahangiri M, Mukhin M, Poloneicki J, Camm J, Xu Q, Association of anti-heat shock protein 65 antibodies with development of postoperative atrial fibrillation. Circulation. 2004; 110(17): 2588-2590
Gang Y, Hnatkova K, Mandal K, Ghuran A, Camm J, Malik M, Preoperative electrocardiographic risk assessment of atrial fibrillation after coronary artery bypass grafting. Journal of Cardiovascular Electrophysiology. 2004; 15(12):1379-86
Fletcher N, Mandal K, Jahangiri M, Surgical glue resembling left atrial thrombus. Interactive Journal of Cardiovascular and Thoracic Surgery. 2004; 3: 409-410
Mandal K, Torsney E, Poloneicki J, Camm J, Xu Q, Jahangiri M, The association of high intracellular, but not serum, heat shock protein 70 with postoperative atrial fibrillation. Annals of Thoracic Surgery. 2005; 79(3): 865-871
Xiao Q, Mandal K, Schett G, Mayr M, Wick G, Oberhollenzer F, Willeit J, Keichl S, Xu Q, Association of serum soluble heat shock protein 60 with carotid atherosclerosis- clinical significance determined in a follow-up study. Stroke. 2005; 36(12):2571-6
Foteinos G, Afzal AR, Mandal K, Jahangiri M, Xu Q, Anti-heat shock protein 60 autoantibodies induce atherosclerosis in ApoE-deficient mice via endothelial damage. Circulation. 2005;112(8):1206-1213
Brecker S, Mandal K, Harrison T, Griffin G, Varghese A, Pennell DJ, Lester J, Jahangiri M., Hydatid cyst of the Heart. The Annals of Royal College of Surgeons of England. 2005; 87(2): 1-4
Mandal K, Brecker S, Madden B, Quinton P, Jahangiri M, Drug allergy mimicking as recurrent endocarditis-A cautionary tale. British Journal of intensive Care. 2005; 2:107-108
Mandal K, Afzal AR, Brecker SJD, Poloneicki J, Xu Q, Jahangiri M, The association of soluble heat shock protein 60 with toll like receptor 4 polymorphism and severity of coronary artery disease. Heart. 2006; 92(5): 683-685
Edfeldt K, Agerberth B, Rottenberg M, Gudmundsson G, Wang XB, Mandal K, Xu Q, Yan Z, Involvement of antimicrobial peptide LL-37 in human atherosclerosis. Arteriosclerosis Thrombosis and Vascular Biology. 2006;26(7):1551-7
Weerasinghe A, Athanasiou T, Philippidis P, Day J, Mandal K, Warren O, Anderson J, Taylor K, Platelet-monocyte pro-coagulant interactions in on-pump surgery. European Journal of CardiothoracicSurgery. 2006; 29(3): 312-318
Afzal AR, Mandal K, Nyamogewa S, Foteinos G, Poloneicki J, Camm AJ, Jahangiri M, Xu Q, The association of Met439Thr substitution in heat shock protein 70 gene with postoperative atrial fibrillation and serum HSP70 level. Cardiology 2007;110(1):45-52
Torsney E, Mandal K, Halliday A, Jahangiri M, Xu Q, Characterization of Progenitor cells in human atherosclerotic lesions. Atherosclerosis. 2007;191(2):259-64
Tavakkoli HM, Saeed I, Mandal K, Kourliouros A, Valencia O, Jahangiri M, Short term outcome following cardiac surgery- a comparison between consultant and trainees performance. Interactive Journal of Cardiovascular and Thoracic Surgery. 2010; Jun;10(6):889-91.
Didangelos A, Xioke Y, Mandal K, Mark B, Jahangiri M, Mayr M, Proteomic characterization of extracellular space components in the human aorta. Mol Cell Proteomics mcp. 2010; Sep; 9(9):2048-62.
Didangelos A, Xioke Y, Mandal K, Jahangiri M, Mayr M, BAS/BSCR9 Proteomic characterization of extracellular space components in the human aorta. Heart. 2010; Sep:96(17): e15
Didangelos A, Yin X, Mandal K, Saje A, Smith A, Xu Q, Jahangiri M, Mayr M, Extracellular matrix composition and remodeling in human abdominal aortic aneurysms: a proteomics approach. Mol Cell Proteomics. 2011 Aug;10(8): M111.008128
REVIEWS
Mandal K, Strategy in screening mammography The Surgeons perspective. Hospital Today. 1998; 12:742-744
Mandal K, Jahangiri M, Xu Q, Autoimmunity to heat shock proteins in atherosclerosis. Autoimmunity Reviews. 2004; 3(2): 31-37
Mandal K, Foteinos G, Jahangiri M, Xu Q, Role of anti-heat shock protein 60 antibodies in Atherosclerosis. Lupus. 2005;14(9):742-6
Jahangiri M, Weir G, Mandal K, Savelieva I, Camm J, Current strategies in the management of atrial fibrillation. Annals of Thoracic Surgery. 2006;82(1):357-364
Warren O, Mandal K, Hadjianastassiou V, Knowlton L, Panesar S, John K, Darzi A, Athanasiou T, Recombinant activated factor VII in cardiac surgery: a systemic review. Annals of Thoracic Surgery. 2007;83(2):707-14
Xu Q, Bernhard Metzler, Jahangiri M, Mandal K, Molecular chaperones and Heat shock proteins in atherosclerosis. American Journal of Physiology- Heart & Circulatory Physiology. 2012 Feb 1;302(3):H506-14.
Killic A, Mandal K, Autoimmunity to Heat Shock Proteins: Pathogenic Role in Atherosclerosis and Potential Therapeutic Implications. Accepted for publication in Autoimmnity Review. 2012 June.
LETTERS / CORRESPONDENCES
Mayr M, Mandal K, Xu Q, Pitfalls of Proteomics. Circulation. 2004; 110(12): e316
Mandal K, Jahangiri M, Mukhin M, Poloneicki J, Camm J, Xu Q, Response to Dr. Auer- Association of anti-heat shock protein 65 antibodies with development of postoperative atrial fibrillation. Circulation. 2005;111(20):e306
BOOK CHAPTERS
Mandal K, Jahangiri M, Xu Q, Autoimmune mechanisms of atherosclerosis. Handbook of experimental pharmacology: arteriosclerosis; influence of diet and drugs. Edited by von Eckardstein A (Springer-Verlag). 2005; 170: 723-743
Mandal K, Chest Trauma. Oxford handbook of cardiothoracic surgery. Edited by Chikwe J (Oxford Speciality Handbooks). 2006; 748-755
Mandal K, Jahangiri M, Xu Q, Endothelial progenitor cells & vascular repair. Cardiac regeneration and stem cell therapy. Edited by Anversa P (Blackwell Scientific). 2007; 57-65
Mandal K, Meneshian A, Pulmunory infections. Johns Hopkins Manual of Cardiothoracic Surgery. 2nd Edition. Edited by Yuh D, Vricella L, Yang S, Doty J (McGraw Hill Publishers- In Press)
Mandal K, Cameron D, Aortic Root Replacement. Johns Hopkins Manual of Cardiothoracic Surgery. 2nd Edition. Edited by Yuh D, Vricella L, Yang S, Doty J (McGraw Hill Publishers- In Press)
Mandal K, Weerasena N, Cardiac surgery in adults with congenital heart disease. Johns Hopkins Manual of Cardiothoracic Surgery. 2nd Edition. Edited by Yuh D, Vricella L, Yang S, Doty J (McGraw Hill Publishers- In Press)
Sodha NR, Mandal K, Cameron DE, Valve Sparing Aortic Root Replacement. Recent Advances in cardiac Surgery. Edited by Moorjani N, Ohri S, Wechsler A (Hodder Arnold Publishers- In Press)
THESIS FOR MASTER OF SURGERY (All India Institute of Medical Sciences 1999)
Role of mammography in detection of non-palpable breast lesions in Indian women above 40 years with a high-risk profile A hospital based prospective study
DOCTORAL THESEIS (University of London 2005)
Soluble heat shock protein 60 and autoantibodies against heat shock protein 65 and oxidized LDL in patients with chronic stable angina
Kumar A, Seenu V, Mohan N, Kaul A, Bhalla A, Batra R, Mandal K, Aggarwal S, Initial experience with day case laparoscopic cholecystectomy in a tertiary care hospital in India. National Medical Journal of India. 1999; 12(3):103-107
Mandal K, West C, The management of immediate post-traumatic seizures in children following minor head injury- time for a multicentre study? Childs Nervous System. 2001; 17(11): 670-673
Mandal K, Jahangiri M, Mukhin M, Poloneicki J, Camm J, Xu Q, Association of anti-heat shock protein 65 antibodies with development of postoperative atrial fibrillation. Circulation. 2004; 110(17): 2588-2590
Gang Y, Hnatkova K, Mandal K, Ghuran A, Camm J, Malik M, Preoperative electrocardiographic risk assessment of atrial fibrillation after coronary artery bypass grafting. Journal of Cardiovascular Electrophysiology. 2004; 15(12):1379-86
Fletcher N, Mandal K, Jahangiri M, Surgical glue resembling left atrial thrombus. Interactive Journal of Cardiovascular and Thoracic Surgery. 2004; 3: 409-410
Mandal K, Torsney E, Poloneicki J, Camm J, Xu Q, Jahangiri M, The association of high intracellular, but not serum, heat shock protein 70 with postoperative atrial fibrillation. Annals of Thoracic Surgery. 2005; 79(3): 865-871
Xiao Q, Mandal K, Schett G, Mayr M, Wick G, Oberhollenzer F, Willeit J, Keichl S, Xu Q, Association of serum soluble heat shock protein 60 with carotid atherosclerosis- clinical significance determined in a follow-up study. Stroke. 2005; 36(12):2571-6
Foteinos G, Afzal AR, Mandal K, Jahangiri M, Xu Q, Anti-heat shock protein 60 autoantibodies induce atherosclerosis in ApoE-deficient mice via endothelial damage. Circulation. 2005;112(8):1206-1213
Brecker S, Mandal K, Harrison T, Griffin G, Varghese A, Pennell DJ, Lester J, Jahangiri M., Hydatid cyst of the Heart. The Annals of Royal College of Surgeons of England. 2005; 87(2): 1-4
Mandal K, Brecker S, Madden B, Quinton P, Jahangiri M, Drug allergy mimicking as recurrent endocarditis-A cautionary tale. British Journal of intensive Care. 2005; 2:107-108
Mandal K, Afzal AR, Brecker SJD, Poloneicki J, Xu Q, Jahangiri M, The association of soluble heat shock protein 60 with toll like receptor 4 polymorphism and severity of coronary artery disease. Heart. 2006; 92(5): 683-685
Edfeldt K, Agerberth B, Rottenberg M, Gudmundsson G, Wang XB, Mandal K, Xu Q, Yan Z, Involvement of antimicrobial peptide LL-37 in human atherosclerosis. Arteriosclerosis Thrombosis and Vascular Biology. 2006;26(7):1551-7
Weerasinghe A, Athanasiou T, Philippidis P, Day J, Mandal K, Warren O, Anderson J, Taylor K, Platelet-monocyte pro-coagulant interactions in on-pump surgery. European Journal of CardiothoracicSurgery. 2006; 29(3): 312-318
Afzal AR, Mandal K, Nyamogewa S, Foteinos G, Poloneicki J, Camm AJ, Jahangiri M, Xu Q, The association of Met439Thr substitution in heat shock protein 70 gene with postoperative atrial fibrillation and serum HSP70 level. Cardiology 2007;110(1):45-52
Torsney E, Mandal K, Halliday A, Jahangiri M, Xu Q, Characterization of Progenitor cells in human atherosclerotic lesions. Atherosclerosis. 2007;191(2):259-64
Tavakkoli HM, Saeed I, Mandal K, Kourliouros A, Valencia O, Jahangiri M, Short term outcome following cardiac surgery- a comparison between consultant and trainees performance. Interactive Journal of Cardiovascular and Thoracic Surgery. 2010; Jun;10(6):889-91.
Didangelos A, Xioke Y, Mandal K, Mark B, Jahangiri M, Mayr M, Proteomic characterization of extracellular space components in the human aorta. Mol Cell Proteomics mcp. 2010; Sep; 9(9):2048-62.
Didangelos A, Xioke Y, Mandal K, Jahangiri M, Mayr M, BAS/BSCR9 Proteomic characterization of extracellular space components in the human aorta. Heart. 2010; Sep:96(17): e15
Didangelos A, Yin X, Mandal K, Saje A, Smith A, Xu Q, Jahangiri M, Mayr M, Extracellular matrix composition and remodeling in human abdominal aortic aneurysms: a proteomics approach. Mol Cell Proteomics. 2011 Aug;10(8): M111.008128
REVIEWS
Mandal K, Strategy in screening mammography The Surgeons perspective. Hospital Today. 1998; 12:742-744
Mandal K, Jahangiri M, Xu Q, Autoimmunity to heat shock proteins in atherosclerosis. Autoimmunity Reviews. 2004; 3(2): 31-37
Mandal K, Foteinos G, Jahangiri M, Xu Q, Role of anti-heat shock protein 60 antibodies in Atherosclerosis. Lupus. 2005;14(9):742-6
Jahangiri M, Weir G, Mandal K, Savelieva I, Camm J, Current strategies in the management of atrial fibrillation. Annals of Thoracic Surgery. 2006;82(1):357-364
Warren O, Mandal K, Hadjianastassiou V, Knowlton L, Panesar S, John K, Darzi A, Athanasiou T, Recombinant activated factor VII in cardiac surgery: a systemic review. Annals of Thoracic Surgery. 2007;83(2):707-14
Xu Q, Bernhard Metzler, Jahangiri M, Mandal K, Molecular chaperones and Heat shock proteins in atherosclerosis. American Journal of Physiology- Heart & Circulatory Physiology. 2012 Feb 1;302(3):H506-14.
Killic A, Mandal K, Autoimmunity to Heat Shock Proteins: Pathogenic Role in Atherosclerosis and Potential Therapeutic Implications. Accepted for publication in Autoimmnity Review. 2012 June.
LETTERS / CORRESPONDENCES
Mayr M, Mandal K, Xu Q, Pitfalls of Proteomics. Circulation. 2004; 110(12): e316
Mandal K, Jahangiri M, Mukhin M, Poloneicki J, Camm J, Xu Q, Response to Dr. Auer- Association of anti-heat shock protein 65 antibodies with development of postoperative atrial fibrillation. Circulation. 2005;111(20):e306
BOOK CHAPTERS
Mandal K, Jahangiri M, Xu Q, Autoimmune mechanisms of atherosclerosis. Handbook of experimental pharmacology: arteriosclerosis; influence of diet and drugs. Edited by von Eckardstein A (Springer-Verlag). 2005; 170: 723-743
Mandal K, Chest Trauma. Oxford handbook of cardiothoracic surgery. Edited by Chikwe J (Oxford Speciality Handbooks). 2006; 748-755
Mandal K, Jahangiri M, Xu Q, Endothelial progenitor cells & vascular repair. Cardiac regeneration and stem cell therapy. Edited by Anversa P (Blackwell Scientific). 2007; 57-65
Mandal K, Meneshian A, Pulmunory infections. Johns Hopkins Manual of Cardiothoracic Surgery. 2nd Edition. Edited by Yuh D, Vricella L, Yang S, Doty J (McGraw Hill Publishers- In Press)
Mandal K, Cameron D, Aortic Root Replacement. Johns Hopkins Manual of Cardiothoracic Surgery. 2nd Edition. Edited by Yuh D, Vricella L, Yang S, Doty J (McGraw Hill Publishers- In Press)
Mandal K, Weerasena N, Cardiac surgery in adults with congenital heart disease. Johns Hopkins Manual of Cardiothoracic Surgery. 2nd Edition. Edited by Yuh D, Vricella L, Yang S, Doty J (McGraw Hill Publishers- In Press)
Sodha NR, Mandal K, Cameron DE, Valve Sparing Aortic Root Replacement. Recent Advances in cardiac Surgery. Edited by Moorjani N, Ohri S, Wechsler A (Hodder Arnold Publishers- In Press)
THESIS FOR MASTER OF SURGERY (All India Institute of Medical Sciences 1999)
Role of mammography in detection of non-palpable breast lesions in Indian women above 40 years with a high-risk profile A hospital based prospective study
DOCTORAL THESEIS (University of London 2005)
Soluble heat shock protein 60 and autoantibodies against heat shock protein 65 and oxidized LDL in patients with chronic stable angina
Research Interests
- Mitral valve repair
- Robotics and advanced imaging in cardiac surgery
- Health care quality and informatics
- Minimally invasive cardiac surgery
More Info
Languages
- English
- Hindi
Memberships
- Halsted Surgical Residents Society of the Johns Hopkins Hospital
- Fellow of the Royal College of Surgeons of Edinburgh
- Fellow of European Society of Cardiology
- Member European Working Group on Pathogenesis of Atherosclerosis
- Fellow of the Royal College of Surgeons of Edinburgh
- Fellow of European Society of Cardiology
- Member European Working Group on Pathogenesis of Atherosclerosis
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