Dr. Michael Lim's surgical interest is in the treatment of primary and metastatic brain tumors as well as pituitary and skull base tumors. He also has an interest in surgical treatments of trigeminal neuralgia. He utilizes the most advanced techniques in neurosurgery including image guided surgery, microsurgery, minimally invasive techniques, and endoscopic surgery.

Dr. Lim also possesses expertise in radiosurgery. He is the Director of the Spine Radiosurgery program. In addition to treating spinal tumors, he is an expert in the treatment of brain tumors, arteriovenous malformations, and trigeminal neuralgia with radiosurgery.

Dr. Lim's primary research interest involves immune-based therapies against brain tumors. His research focuses on understanding the mechanisms of immune evasion by primary brain tumors with the goal of translation to novel therapies against gliomas. Dr. Lim also performs clinical research. He publishes extensively in radiosurgery and also has interests in brain tumor clinical trials for which he works closely with the neuro-oncologists in a team approach.