Murugappan Ramanathan, MD
Title(s): Assistant Professor of Otolaryngology-Head and Neck Surgery
Appointment Phone:
301-896-3330
Primary Location:
Johns Hopkins Otolaryngology Head and Neck Surgery - Suburban Hospital Outpatient Center
Expertise:
Cerebrospinal Fluid Leaks, Chronic Sinusitis with Polyps, Endoscopic Frontal Sinus Surgery, Nasal Obstruction, Nasal Polyps, Otolaryngology, Paranasal Sinus Tumors, Revision Endoscopic Sinus Surgery, Revision Frontal Sinus Surgery, Sinus Problems, Sinus Problems - Adult, Sinusitis, Sinusitis and Nasal Polyposis, Skull Base Tumors
Education and Experience
Training
- University of Texas Medical Branch School of Medicine (Galveston TX)/ (2004)
Residencies
- The Johns Hopkins Hospital (Baltimore MD)/ Otolaryngology (2009)
Certifications
- Otolaryngology, American Board of Otolaryngology (2010)
Locations
Johns Hopkins Otolaryngology Head and Neck Surgery - Suburban Hospital Outpatient Center
6420 Rockledge Drive
Bethesda, MD 20817
Phone: 301-896-3330
Appointment Phone: 301-896-3330
Location Map
Johns Hopkins Outpatient Center
601 N. Caroline Street
Baltimore, MD 21287
Phone: 443-287-2000
Appointment Phone: 443-287-2000
Location Map
Department / Division
-
Otolaryngology - Head and Neck Surgery - Johns Hopkins Sinus Center
Centers/Institutes
Centers / Institutes
- Sinus Center
Bio
Biography
Dr. Murray Ramanathan is a fellowship-trained rhinologist and sinus/skull base tumor specialist who cares for children and adults with difficult or problematic sinus and nasal issues, such as: Chronic sinusitis that may require endoscopic sinus surgery; Sinonasal tumors and skull base tumors; Cerebrospinal fluid (CSF) leaks; and Graves'' orbitopathy or nasolacrimal duct obstruction.
Expertise
- Cerebrospinal Fluid Leaks
- Chronic Sinusitis with Polyps
- Endoscopic Frontal Sinus Surgery
- Nasal Obstruction
- Nasal Polyps
- Otolaryngology
- Paranasal Sinus Tumors
- Revision Endoscopic Sinus Surgery
- Revision Frontal Sinus Surgery
- Sinus Problems
- Sinus Problems - Adult
- Sinusitis
- Sinusitis and Nasal Polyposis
- Skull Base Tumors
Research
Research and Publications
Murugappan Ramanathan, Jr., Won-Kyung Lee, and Andrew P. Lane. Increased Expression of Acidic Mammalian Chitinase (AMCase) is Associated With Chronic Rhinosinusitis with Nasal Polyps. Am J. Rhinol. 2006 May-Jun; 20(3):330-335
Murugappan Ramanathan, Jr., Ernst W. Spannhake, and Andrew P. Lane. Decreased Expression of Interleukin 22 Receptor is Associated With Chronic Rhinosinusitis with Nasal Polyps. Laryngoscope 2007 Oct; 117(10):1839-43
Murugappan Ramanathan, Jr. and Andrew P. Lane. A Comparison of Experimental Methods in Molecular Chronic Rhinosinusitis Research. Am J. Rhinol. 2007 May-Jun; 21(3): 373-7
Murugappan Ramanathan, Jr., Won K. Lee, Marc G. Dubin, Sandra Lin, Ernst W. Spannhake, and Andrew P. Lane. Sinonasal Epithelial Cell Expression of Toll-Like Receptor 9 is Decreased in Chronic Rhinosinusitis with Nasal Polyps. Am. J. Rhinol 2007 Jan-Feb; 21(1): 110-116
Murugappan Ramanathan, Jr. and Andrew P. Lane. Innate Immunity of the Sinonasal Cavity and its Role in Chronic Rhinosinusitis. Otolaryngol Head Neck Surg. 2007 Mar; 136(3):348-56. Review.
Won K. Lee, Murugappan Ramanathan, Jr., Ernst. W. Spannhake, and Andrew P. Lane. The cigarette smoke component acrolein inhibits expression of the innate immune components IL-8 and HBD-2 by sinonasal epithelial cells. Am. J. Rhinol. 2007 Nov-Dec; 21 (6) 658-663
Murugappan Ramanathan, Jr., Won K. Lee, Ernst W. Spannhake, and Andrew P. Lane. Th2 Cytokines Associated with Chronic Rhinosinusitis with Polyps Down-Regulate the Anti-Microbial Immune Function of Human Sinonasal Epithelial Cells. Am. J. Rhinol. 2008 Mar-Apr; 22(2) 115-21
Ashley Lalaker, Louis Nkrumah, Won K. Lee, Murugappan Ramanathan, Jr., and Andrew P. Lane. Dust Mite Antigen Modulates Innate Immune Gene Expression By Human Sinonasal Epithelial Cells. Am. J. Rhinol Allergy 2009 Jan-Feb; 23(1)8-14
Douglas Reh, Yadong Wang, Leda Pawliuk, Murugappan Ramanathan, Jr., and Andrew P. Lane. Treatment-recalcitrant chronic rhinosinusitis with polyps is associated with altered epithelial cell expression of interleukin-33. Am J. Rhinol Allergy 2010 Mar;24(2):105-9.
Murugappan Ramanathan, Jr., Justin Turner, and Andrew P. Lane. Technological Advances in Rhinologic Basic Science Research. Otolaryngology Clinics 2009. Oct; 42(5):867-81
Murugappan Ramanathan, Jr., Ernst W. Spannhake, and Andrew P. Lane. Decreased Expression of Interleukin 22 Receptor is Associated With Chronic Rhinosinusitis with Nasal Polyps. Laryngoscope 2007 Oct; 117(10):1839-43
Murugappan Ramanathan, Jr. and Andrew P. Lane. A Comparison of Experimental Methods in Molecular Chronic Rhinosinusitis Research. Am J. Rhinol. 2007 May-Jun; 21(3): 373-7
Murugappan Ramanathan, Jr., Won K. Lee, Marc G. Dubin, Sandra Lin, Ernst W. Spannhake, and Andrew P. Lane. Sinonasal Epithelial Cell Expression of Toll-Like Receptor 9 is Decreased in Chronic Rhinosinusitis with Nasal Polyps. Am. J. Rhinol 2007 Jan-Feb; 21(1): 110-116
Murugappan Ramanathan, Jr. and Andrew P. Lane. Innate Immunity of the Sinonasal Cavity and its Role in Chronic Rhinosinusitis. Otolaryngol Head Neck Surg. 2007 Mar; 136(3):348-56. Review.
Won K. Lee, Murugappan Ramanathan, Jr., Ernst. W. Spannhake, and Andrew P. Lane. The cigarette smoke component acrolein inhibits expression of the innate immune components IL-8 and HBD-2 by sinonasal epithelial cells. Am. J. Rhinol. 2007 Nov-Dec; 21 (6) 658-663
Murugappan Ramanathan, Jr., Won K. Lee, Ernst W. Spannhake, and Andrew P. Lane. Th2 Cytokines Associated with Chronic Rhinosinusitis with Polyps Down-Regulate the Anti-Microbial Immune Function of Human Sinonasal Epithelial Cells. Am. J. Rhinol. 2008 Mar-Apr; 22(2) 115-21
Ashley Lalaker, Louis Nkrumah, Won K. Lee, Murugappan Ramanathan, Jr., and Andrew P. Lane. Dust Mite Antigen Modulates Innate Immune Gene Expression By Human Sinonasal Epithelial Cells. Am. J. Rhinol Allergy 2009 Jan-Feb; 23(1)8-14
Douglas Reh, Yadong Wang, Leda Pawliuk, Murugappan Ramanathan, Jr., and Andrew P. Lane. Treatment-recalcitrant chronic rhinosinusitis with polyps is associated with altered epithelial cell expression of interleukin-33. Am J. Rhinol Allergy 2010 Mar;24(2):105-9.
Murugappan Ramanathan, Jr., Justin Turner, and Andrew P. Lane. Technological Advances in Rhinologic Basic Science Research. Otolaryngology Clinics 2009. Oct; 42(5):867-81
Research Interests
- Molecular and immunologic (innate and adaptive) mechanisms underlying the pathogenesis of chronic rhinosinusitis with nasal polyps
- Role of Allergy and Environmental pollutants in propagating sinonasal inflammation
More Info
Languages
- English
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