Title(s):
Assistant Professor of Neurology
Assistant Professor of Pediatrics
Assistant Professor of Pediatrics
Director, Basic Epilepsy Research, Pediatric Epilepsy Division
Appointment Phone:
410-955-9100
Primary Location:
The Johns Hopkins Hospital
Expertise:
Epilepsy, Ketogenic diet, Neurology
Education and Experience
Training
- Northwestern University The Feinberg School of Medicine (Chicago IL)/ (1994)
Residencies
- The Johns Hopkins Hospital (Baltimore MD)/ Neurology (2005)
- National Naval Medical Center (Bethesda) (Bethesda MD)/ Pediatrics (1997)
Fellowships
- The Johns Hopkins Hospital (Baltimore MD)/ Neurology (2007)
Certifications
- Pediatrics, American Board of Pediatrics (2010)
- Neurology/Special Child Neurology, American Board of Psychiatry & Neurology (2006)
Locations
The Johns Hopkins Hospital
600 N. Wolfe Street
Hospital Main Entrance - Sheikh Zayed Tower
Baltimore, MD 21287
Phone: 410-955-9100
Appointment Phone: 410-955-9100
Fax: 410-614-0373
Location Map
Department / Division
-
Neurology - Pediatric Neurology
Centers/Institutes
Centers / Institutes
- Epilepsy Center
- Pediatric Neurology Center
Bio
Biography
Dr. Adam Hartman focuses on treating children with epilepsy, with an emphasis on those whose seizures have not been adequately controlled with medication. As one of the Attending Physicians in the Epilepsy Monitoring Unit, he evaluates and manages patients in his clinic who may be candidates for epilepsy surgery, including those with Rasmussen syndrome, brain malformations, and perinatal strokes. Patients who may not be surgery candidates due to inborn errors of metabolism (particularly mitochondrial disorders) also are a special interest for Dr. Hartman. He is the Co-Director of the Neurology Intensive Care Nursery and is an Attending Physician on the Pediatric Neurology Inpatient Service.
Dr. Hartmans laboratory is focused on discovering the anticonvulsant and disease-modifying mechanisms underlying several types of metabolism-based therapy for epilepsy, including the ketogenic diet. He is working at the Johns Hopkins Bloomberg School of Public Health with J. Marie Hardwick, PhD on this project.
Dr. Adam Hartman received his medical degree from Northwestern University Medical School. After completing his residency in Pediatrics in the National Capital Uniformed Services Pediatric Residency Program (National Naval Medical Center, Walter Reed Army Medical Center), he served as a general pediatrician in the US Navy for five years (the last as division head of general pediatrics at Naval Medical Center San Diego). He completed his residency in pediatric neurology and a fellowship in clinical neurophysiology/pediatric epilepsy, both at Johns Hopkins. During his residency and fellowship, Dr. Hartman worked in the Epilepsy Research Section, National Institute of Neurological Disorders and Stroke, NIH under the direction of Michael Rogawski, MD.
Dr. Hartmans laboratory is focused on discovering the anticonvulsant and disease-modifying mechanisms underlying several types of metabolism-based therapy for epilepsy, including the ketogenic diet. He is working at the Johns Hopkins Bloomberg School of Public Health with J. Marie Hardwick, PhD on this project.
Dr. Adam Hartman received his medical degree from Northwestern University Medical School. After completing his residency in Pediatrics in the National Capital Uniformed Services Pediatric Residency Program (National Naval Medical Center, Walter Reed Army Medical Center), he served as a general pediatrician in the US Navy for five years (the last as division head of general pediatrics at Naval Medical Center San Diego). He completed his residency in pediatric neurology and a fellowship in clinical neurophysiology/pediatric epilepsy, both at Johns Hopkins. During his residency and fellowship, Dr. Hartman worked in the Epilepsy Research Section, National Institute of Neurological Disorders and Stroke, NIH under the direction of Michael Rogawski, MD.
Physician Title
Director, Basic Epilepsy Research, Pediatric Epilepsy Division
Awards and Honors
1989 Phi Beta Kappa
1989 Departmental Honors
1989 Lewis Sarrett Scholarship Prize in Chemistry
1991-1992 Howard Hughes Medical Institute - National Institutes of Health Research Scholars Program
1996 Howard Johnson Award for Housestaff Research, Uniformed Services Pediatric Seminar,American Academy of Pediatrics
2002 Preceptor of the Year, Interservice Physician Assistant Program, Naval School of Health Sciences
2002 Francis C. Rash Award (Teacher of the Year), Naval Medical Center San Diego Pediatric Residency Program
2005 Jay Slotkin Award (Best Resident Research Project), Department of Neurology, Johns Hopkins Hospital
2006 Merritt-Putnam Award, Epilepsy Foundation
1989 Departmental Honors
1989 Lewis Sarrett Scholarship Prize in Chemistry
1991-1992 Howard Hughes Medical Institute - National Institutes of Health Research Scholars Program
1996 Howard Johnson Award for Housestaff Research, Uniformed Services Pediatric Seminar,American Academy of Pediatrics
2002 Preceptor of the Year, Interservice Physician Assistant Program, Naval School of Health Sciences
2002 Francis C. Rash Award (Teacher of the Year), Naval Medical Center San Diego Pediatric Residency Program
2005 Jay Slotkin Award (Best Resident Research Project), Department of Neurology, Johns Hopkins Hospital
2006 Merritt-Putnam Award, Epilepsy Foundation
Expertise
- Epilepsy
- Ketogenic diet
- Neurology
Professional Highlights
Dr. Adam Hartman is a co-editor of Treatment of Pediatric Neurologic Disorders, and has authored other research publications and textbook chapters on metabolism-based therapy and epilepsy surgery. He is the Associate Program Director for the Pediatric Neurology Residency.
Research
Research and Publications
Research Publications
Chatterton RT, Jr., Hartman AL, Lynn DE, Hickson RC. Exercise-Induced Ovarian Dysfunction in the Rat. Proc Soc Exp Biol Med 1990;193:220-224.
Hartman AL. The Role of Military Strategies in Medical Thinking. Perspec Biol Med 1993;36:177-183.
Malik KF, Kim J, Hartman AL, Kim P, Young WS, III. Binding Preferences of the POU Domain Protein Brain-4: Implications for Autoregulation. Mol Brain Res 1996;38:209-221.
Hartman A, Stocker JT, and Moriarty R. A 7-Week-Old Male with Respiratory Congestion (Grand Rounds). J. Pediatr. 1998;133:457-462.
Hartman AL, Van Bennekom T. An Infant with Propionic Acidemia. Pediatr Rev 2002;23:284, 288-290.
Hartman AL, Comi AM. Case 4: Just a Bruise? Medscape General Medicine. Nov 21, 2003. Available at: http://www.medscape.com/viewarticle/464767
Winnick S, Lucas DO, Hartman AL, Toll D. How do you improve compliance? Pediatrics 2005;115:e718-e724.
Hartman AL, Kossoff EH. Epilepsy surgery for the neurocutaneous disorders. Semin Pediatr Neurol 2006;13:63-67.
Gasior M, Rogawski MA, Hartman AL. Neuroprotective and disease-modifying effects of the ketogenic diet. Behav Pharmacol 2006;17:431-439.
Hartman AL, Vining EPGV. Clinical Aspects of the Ketogenic Diet. Epilepsia 2007;48:31-42.
Freeman JM, Kossoff EH, Hartman AL. The Ketogenic Diet: One Decade Later (State-of-the-Art Review Article). Pediatrics 2007;119:535-543.
Gasior M, French A, Joy M, Tang R, Hartman AL, Rogawski MA. The Anticonvulsant Activity of Acetone, the Major Ketone Body in the Ketogenic Diet, Is Not Dependent on Its Metabolites Acetol, 1,2-Propanediol, Methylglyoxal or Pyruvic Acid. Epilepsia 2007;48:793-800.
Hartman AL, Gasior M, Vining EPG, Rogawski MA. The Neuropharmacology of the Ketogenic Diet. Pediatric Neurology 2007;36:281-292.
Hartman AL, Lesser RP. Update on Epilepsy and Cerebral Localization. Curr Neurol Neurosci Rep 2007;7:498-507.
Hartman AL, Lyle M, Rogawski MA Gasior M. Efficacy of the Ketogenic Diet in the 6-Hz Seizure Test. Epilepsia 2008;49:334-339 (published online 12/07).
Baranano KW, Hartman AL. The ketogenic diet: uses in epilepsy and other neurologic illnesses. Curr Treat Options Neurol 2008;10:410-419.
Hartman AL. Does the effectiveness of the ketogenic diet in different epilepsies yield insights into its mechanisms? Epilepsia 2008;49(Suppl 8):53-56.
Graham EM, Ruis KA, Hartman AL, Northington FJ, Fox HE. A Systematic Review of the Role of Intrapartum Hypoxia-ischemia in the Causation of Neonatal Encephalopathy. Am J Obstet Gynecol 2008, 199:587-595.
Hartman AL, Lunney KM, Serena JE. Pediatric Stroke: Do clinical factors predict delays in presentation? J Pediatr. 2008 Dec 24. [Epub ahead of print].
Kossoff EH, Hartman AL, Rubenstein JE, Vining EP. High-dose oral prednisolone for infantile spasms: an effective and less expensive alternative to ACTH. Epilepsy Behav 2009;14:674-676.
Morrison PF, Pyzik PL, Hamdy R, Hartman AL, Kossoff EK. The influence of concurrent anticonvulsants on the efficacy of the ketogenic diet. Epilepsia 2009, in press.
Book Chapters
Hartman AL. Seizures. In: JC Woodhead, ed. Pediatric Clerkship Guide. St. Louis:Mosby, 2003:327-333.
Hartman AL. Neurology. In: JC Woodhead, ed. Pediatric Clerkship Guide. St. Louis:Mosby, 2003:583-595.
Hartman AL, Comi AM. Mitochondrial Disorders. In: HS Singer, EH Kossoff, AL Hartman, TO Crawford, eds. Treatment of Pediatric Neurologic Disorders. New York:Taylor & Francis, 2005
Hartman AL, Vining EPG. Febrile Seizures. In: RT Johnson, JW Griffin, JC McArthur, eds. Current Therapy in Neurologic Disease. Philadelphia:Mosby, 2006
Hartman AL, Singer HS. Tourette Syndrome and Associated Neurobehavioral Problems. In: Accardo PJ, ed. Capute & Accardos Neurodevelopmental Disabilities in Infancy and Childhood, 3rd ed. Baltimore:Brookes, 2008
Hartman A. Seizures. In: JC Woodhead, ed. Pediatric Clerkship Guide, 2nd ed. St. Louis:Mosby, 2008:327-333.
Hartman A. Neurology. In: JC Woodhead, ed. Pediatric Clerkship Guide, 2nd ed. St. Louis:Mosby, 2008:604-617.
Hartman AL. Normal Anatomy of the Cerebrospinal Fluid Compartment. In: Irani DN, ed. Cerebrospinal Fluid in Clinical Practice. Philadeplphia:Saunders, 2009.
Hartman AL, Vining, EP. Isolated Seizures and Epileptic Disorders. In: Irani DN, ed. Cerebrospinal Fluid in Clinical Practice. Philadeplphia:Saunders, 2009.
Chatterton RT, Jr., Hartman AL, Lynn DE, Hickson RC. Exercise-Induced Ovarian Dysfunction in the Rat. Proc Soc Exp Biol Med 1990;193:220-224.
Hartman AL. The Role of Military Strategies in Medical Thinking. Perspec Biol Med 1993;36:177-183.
Malik KF, Kim J, Hartman AL, Kim P, Young WS, III. Binding Preferences of the POU Domain Protein Brain-4: Implications for Autoregulation. Mol Brain Res 1996;38:209-221.
Hartman A, Stocker JT, and Moriarty R. A 7-Week-Old Male with Respiratory Congestion (Grand Rounds). J. Pediatr. 1998;133:457-462.
Hartman AL, Van Bennekom T. An Infant with Propionic Acidemia. Pediatr Rev 2002;23:284, 288-290.
Hartman AL, Comi AM. Case 4: Just a Bruise? Medscape General Medicine. Nov 21, 2003. Available at: http://www.medscape.com/viewarticle/464767
Winnick S, Lucas DO, Hartman AL, Toll D. How do you improve compliance? Pediatrics 2005;115:e718-e724.
Hartman AL, Kossoff EH. Epilepsy surgery for the neurocutaneous disorders. Semin Pediatr Neurol 2006;13:63-67.
Gasior M, Rogawski MA, Hartman AL. Neuroprotective and disease-modifying effects of the ketogenic diet. Behav Pharmacol 2006;17:431-439.
Hartman AL, Vining EPGV. Clinical Aspects of the Ketogenic Diet. Epilepsia 2007;48:31-42.
Freeman JM, Kossoff EH, Hartman AL. The Ketogenic Diet: One Decade Later (State-of-the-Art Review Article). Pediatrics 2007;119:535-543.
Gasior M, French A, Joy M, Tang R, Hartman AL, Rogawski MA. The Anticonvulsant Activity of Acetone, the Major Ketone Body in the Ketogenic Diet, Is Not Dependent on Its Metabolites Acetol, 1,2-Propanediol, Methylglyoxal or Pyruvic Acid. Epilepsia 2007;48:793-800.
Hartman AL, Gasior M, Vining EPG, Rogawski MA. The Neuropharmacology of the Ketogenic Diet. Pediatric Neurology 2007;36:281-292.
Hartman AL, Lesser RP. Update on Epilepsy and Cerebral Localization. Curr Neurol Neurosci Rep 2007;7:498-507.
Hartman AL, Lyle M, Rogawski MA Gasior M. Efficacy of the Ketogenic Diet in the 6-Hz Seizure Test. Epilepsia 2008;49:334-339 (published online 12/07).
Baranano KW, Hartman AL. The ketogenic diet: uses in epilepsy and other neurologic illnesses. Curr Treat Options Neurol 2008;10:410-419.
Hartman AL. Does the effectiveness of the ketogenic diet in different epilepsies yield insights into its mechanisms? Epilepsia 2008;49(Suppl 8):53-56.
Graham EM, Ruis KA, Hartman AL, Northington FJ, Fox HE. A Systematic Review of the Role of Intrapartum Hypoxia-ischemia in the Causation of Neonatal Encephalopathy. Am J Obstet Gynecol 2008, 199:587-595.
Hartman AL, Lunney KM, Serena JE. Pediatric Stroke: Do clinical factors predict delays in presentation? J Pediatr. 2008 Dec 24. [Epub ahead of print].
Kossoff EH, Hartman AL, Rubenstein JE, Vining EP. High-dose oral prednisolone for infantile spasms: an effective and less expensive alternative to ACTH. Epilepsy Behav 2009;14:674-676.
Morrison PF, Pyzik PL, Hamdy R, Hartman AL, Kossoff EK. The influence of concurrent anticonvulsants on the efficacy of the ketogenic diet. Epilepsia 2009, in press.
Book Chapters
Hartman AL. Seizures. In: JC Woodhead, ed. Pediatric Clerkship Guide. St. Louis:Mosby, 2003:327-333.
Hartman AL. Neurology. In: JC Woodhead, ed. Pediatric Clerkship Guide. St. Louis:Mosby, 2003:583-595.
Hartman AL, Comi AM. Mitochondrial Disorders. In: HS Singer, EH Kossoff, AL Hartman, TO Crawford, eds. Treatment of Pediatric Neurologic Disorders. New York:Taylor & Francis, 2005
Hartman AL, Vining EPG. Febrile Seizures. In: RT Johnson, JW Griffin, JC McArthur, eds. Current Therapy in Neurologic Disease. Philadelphia:Mosby, 2006
Hartman AL, Singer HS. Tourette Syndrome and Associated Neurobehavioral Problems. In: Accardo PJ, ed. Capute & Accardos Neurodevelopmental Disabilities in Infancy and Childhood, 3rd ed. Baltimore:Brookes, 2008
Hartman A. Seizures. In: JC Woodhead, ed. Pediatric Clerkship Guide, 2nd ed. St. Louis:Mosby, 2008:327-333.
Hartman A. Neurology. In: JC Woodhead, ed. Pediatric Clerkship Guide, 2nd ed. St. Louis:Mosby, 2008:604-617.
Hartman AL. Normal Anatomy of the Cerebrospinal Fluid Compartment. In: Irani DN, ed. Cerebrospinal Fluid in Clinical Practice. Philadeplphia:Saunders, 2009.
Hartman AL, Vining, EP. Isolated Seizures and Epileptic Disorders. In: Irani DN, ed. Cerebrospinal Fluid in Clinical Practice. Philadeplphia:Saunders, 2009.
Research Interests
- Epilepsy
- Ketogenic diet
- Seizure models
More Info
Languages
- English
Memberships
1998-present Fellow, American Academy of Pediatrics (AAP)
1999-present Clinical Pharmacy and Therapeutics Section, AAP
1999-present Uniformed Services Section, AAP
2000-2008 Ambulatory Pediatric Association
2006-present American Clinical Neurophysiology Society
2006 Diplomate, American Board of Psychiatry and Neurology
2007-present Member, American Academy of Neurology
2007-present Member, American Epilepsy Society
2007-present Member, Child Neurology Society
2007-present Abilities Network (Epilepsy Foundation), Professional Advisory Board
2008-present Section on Neurology, AAP
2008-present Infant Seizure Society (Japan), Corresponding Member
1999-present Clinical Pharmacy and Therapeutics Section, AAP
1999-present Uniformed Services Section, AAP
2000-2008 Ambulatory Pediatric Association
2006-present American Clinical Neurophysiology Society
2006 Diplomate, American Board of Psychiatry and Neurology
2007-present Member, American Academy of Neurology
2007-present Member, American Epilepsy Society
2007-present Member, Child Neurology Society
2007-present Abilities Network (Epilepsy Foundation), Professional Advisory Board
2008-present Section on Neurology, AAP
2008-present Infant Seizure Society (Japan), Corresponding Member
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