Title(s):
Professor of Medicine
Director, Pulmonary Hypertension Program
Appointment Phone:
410-550-5864
Primary Location:
The Johns Hopkins Hospital
Expertise:
Critical Care Medicine, General Internal Medicine, Pulmonary Hypertension
Education and Experience
Training
- Faculte' de Medecine Lariborsiere - (Paris )/ (1981)
Residencies
- Brigham and Women's Hospital (Boston MA)/ (1984)
Fellowships
- Tufts - New England Medical Center Hospitals (Boston MA)/ (1988)
- Massachusetts General Hospital (Boston MA)/ (1987)
Certifications
- Pulmonary Disease, American Board of Internal Medicine (1986)
- Internal Medicine, American Board of Internal Medicine (1984)
Locations
The Johns Hopkins Hospital
600 N. Wolfe Street
1830 Building Room 5th Floor
Baltimore, MD 21287
Phone: 410-955-3467
Appointment Phone: 410-550-5864
Fax: 410-614-7451
Location Map
Johns Hopkins Bayview Medical Center
4940 Eastern Avenue
Baltimore, MD 21224
Phone: 410-550-0545
Appointment Phone: 410-550-5864
Fax: 410-550-2612
Location Map
Johns Hopkins Outpatient Center
601 N. Caroline Street
Baltimore, MD 21287
Appointment Phone: 410-955-3467
Fax: 410-614-7451
Location Map
Department / Division
-
Medicine - Pulmonary and Critical Care Medicine
Centers/Institutes
Bio
Physician Title
Director, Pulmonary Hypertension Program
Awards and Honors
1986 Recipient of the Winthrop-Breon/ACCP Scholar Award for Outstanding Original Scientific Research, American Lung Association/American Thoracic Society
1988-1990 Recipient of Edward Livingston Trudeau Scholar Award: declined due to acceptance of Clinical Investigator Award
2001 Oliver Smith Award (Recognizing excellence, compassion, and extraordinary service and caring at the New England Medical Center)
2001 Tufts University School of Medicine, Third Year Clerkship, Excellence in Teaching Award.
2002 Tufts University School of Medicine, Third Year Clerkship, Excellence in Teaching Award.
2008 Chair, Program Committee, Pulmonary Circulation, American Thoracic Society
2008 The David M Levine Excellence in Mentoring Award, Johns Hopkins University Department of Medicine
1988-1990 Recipient of Edward Livingston Trudeau Scholar Award: declined due to acceptance of Clinical Investigator Award
2001 Oliver Smith Award (Recognizing excellence, compassion, and extraordinary service and caring at the New England Medical Center)
2001 Tufts University School of Medicine, Third Year Clerkship, Excellence in Teaching Award.
2002 Tufts University School of Medicine, Third Year Clerkship, Excellence in Teaching Award.
2008 Chair, Program Committee, Pulmonary Circulation, American Thoracic Society
2008 The David M Levine Excellence in Mentoring Award, Johns Hopkins University Department of Medicine
Expertise
- Critical Care Medicine
- General Internal Medicine
- Pulmonary Hypertension
Research
Research and Publications
5Grigoryev DN, Fisher MR, Mathai SC, Girgis RE, Zaiman AL, Housten-Harris T, Cheadle C, Hummers LK, Champion HC, Garcia JGN, Barnes KC, Wigley FM, Tuder RM, Hassoun PM. Identification of candidate genes in scleroderma-related pulmonary arterial hypertension. Transl Res. 2008 Apr;151(4):197-207, 2008.
Forfia P, Mathai SC, Fisher MR, Housten-Harris T, Hemnes AR, Champion HC, Girgis RE, Hassoun PM. Hyponatremia predicts right heart failure and poor survival in pulmonary arterial hypertension. Am J Respir Crit Care Med 177(12):1364-9, 2008.
Le A, Damarala M, Boueiz A, Pae HH, Skirball J, Hasan E, Peng X, Damico R, Chesley A, Crow MT, Reddy SP, Tuder RM, Hassoun PM. Alveolar Cell Apoptosis is Dependent on p38-MAPK-Mediated Activation of Xanthine Oxidoreductase in Ventilator-Induced Lung Injury. J Appl Physiol 105(4):1282-1290, 2008.
Dodd-o J, Hristopoulos, Scharfstein D, Brower RG, Hassoun PM, King LS, Becker PM, Liu M, Wang W, Hassoun HT, Rabb H. Interactive effects of mechanical ventilation and kidney health on lung function in an in vivo mouse model. Am J Physiol: Lung Cell Mol Physiol Oct 10. [Epub ahead of print]PMID: 18849441 2008.
Bierman A, Yerrapureddy A, Reddy NM, Hassoun PM, Reddy SP. Epidermal growth factory receptor (EGFR) regulates mechanical ventilation-induced lung injury in mice. Transl Res 152(6): 265-272, 2008.
Schmidt EP, Damarla M, Rentsendorj O, Servinsky LE, Zhu P, Moldobaeva A, Gonzalez A, Hassoun PM, Pearse DB. Soluble guanylyl cyclase contributes to ventilator-induced lung injury in mice. Am J Physiol Lung Cell Mol Physiol 295(6) L1056-l1065, 2008.
Fisher MR, Forfia PR, Chamera E, Housten-Harris T, Champion HC, Girgis RE, Corretti MC, Hassoun PM. Accuracy of Doppler echocardiography in the hemodynamic assessment of pulmonary hypertension. Am J Respir Crit Care Med 179(7):615-21, 2009.
Damarla M, Hasan E, Boueiz A, Le A, Pae HH, Montouchet C, Kolb T, Simms T, Myers A, Kayyali US, Gaestel M, Peng X, Reddy SP, Damico R, Hassoun PM. Mitogen activated protein kinase activated protein kinase 2 regulates actin polymerization and vascular leak in ventilator associated lung injury. PLoS ONE 4(2):E4600. Epub Feb 25, 2009.
Barnett CF, Bonura EJ, Nathan SD, Ahmad S, Shlobin OA, Osei K, Zaiman AL, Hassoun PM, Moller DR, Barnett SD, Girgis RE. Treatment of sarcoidosis-associated pulmonary hypertension: A two-center experience. Chest 2008 Dec 31. [Epub ahead of print] PMID: 19118270.
Finigan JH, Boueiz A, Wilkinson E, Damico R, Skirball J, Pae HH, Damarla N, Hasan E, Pearse DB, Reddy SP, Grigoryev D, Cheadle C, Esmon CT, Garcia JGN, Hassoun PM. Activated Protein C arotects against ventilator-induced pulmonary capillary leak. Am J Physiol Lung Cell Mol Physiol. Apr 10 2009. [Epub ahead of print]
Mathai SC, Hummers LK, Champion HC, Wigley FM, Zaiman A, Hassoun PM, Girgis RE. Survival in pulmonary hypertension associated with the scleroderma spectrum of diseases: Impact of interstitial lung disease. Arthritis Rheum 60(2):569-577, 2009.
Angelini DJ, Su Q. Yamaji-Kegan K, Fan C. Teng X, Hassoun PM, Yang SC, Champion HC, Tuder RM, Johns RA. Resistin-like molecule-{beta} (RELM{beta} in scleroderma-associated pulmonary hypertension. Am J Respir Cell Mol Biol 2009 Feb 9 [Epub ahead of print].
Forfia P, Mathai SC, Fisher MR, Housten-Harris T, Hemnes AR, Champion HC, Girgis RE, Hassoun PM. Hyponatremia predicts right heart failure and poor survival in pulmonary arterial hypertension. Am J Respir Crit Care Med 177(12):1364-9, 2008.
Le A, Damarala M, Boueiz A, Pae HH, Skirball J, Hasan E, Peng X, Damico R, Chesley A, Crow MT, Reddy SP, Tuder RM, Hassoun PM. Alveolar Cell Apoptosis is Dependent on p38-MAPK-Mediated Activation of Xanthine Oxidoreductase in Ventilator-Induced Lung Injury. J Appl Physiol 105(4):1282-1290, 2008.
Dodd-o J, Hristopoulos, Scharfstein D, Brower RG, Hassoun PM, King LS, Becker PM, Liu M, Wang W, Hassoun HT, Rabb H. Interactive effects of mechanical ventilation and kidney health on lung function in an in vivo mouse model. Am J Physiol: Lung Cell Mol Physiol Oct 10. [Epub ahead of print]PMID: 18849441 2008.
Bierman A, Yerrapureddy A, Reddy NM, Hassoun PM, Reddy SP. Epidermal growth factory receptor (EGFR) regulates mechanical ventilation-induced lung injury in mice. Transl Res 152(6): 265-272, 2008.
Schmidt EP, Damarla M, Rentsendorj O, Servinsky LE, Zhu P, Moldobaeva A, Gonzalez A, Hassoun PM, Pearse DB. Soluble guanylyl cyclase contributes to ventilator-induced lung injury in mice. Am J Physiol Lung Cell Mol Physiol 295(6) L1056-l1065, 2008.
Fisher MR, Forfia PR, Chamera E, Housten-Harris T, Champion HC, Girgis RE, Corretti MC, Hassoun PM. Accuracy of Doppler echocardiography in the hemodynamic assessment of pulmonary hypertension. Am J Respir Crit Care Med 179(7):615-21, 2009.
Damarla M, Hasan E, Boueiz A, Le A, Pae HH, Montouchet C, Kolb T, Simms T, Myers A, Kayyali US, Gaestel M, Peng X, Reddy SP, Damico R, Hassoun PM. Mitogen activated protein kinase activated protein kinase 2 regulates actin polymerization and vascular leak in ventilator associated lung injury. PLoS ONE 4(2):E4600. Epub Feb 25, 2009.
Barnett CF, Bonura EJ, Nathan SD, Ahmad S, Shlobin OA, Osei K, Zaiman AL, Hassoun PM, Moller DR, Barnett SD, Girgis RE. Treatment of sarcoidosis-associated pulmonary hypertension: A two-center experience. Chest 2008 Dec 31. [Epub ahead of print] PMID: 19118270.
Finigan JH, Boueiz A, Wilkinson E, Damico R, Skirball J, Pae HH, Damarla N, Hasan E, Pearse DB, Reddy SP, Grigoryev D, Cheadle C, Esmon CT, Garcia JGN, Hassoun PM. Activated Protein C arotects against ventilator-induced pulmonary capillary leak. Am J Physiol Lung Cell Mol Physiol. Apr 10 2009. [Epub ahead of print]
Mathai SC, Hummers LK, Champion HC, Wigley FM, Zaiman A, Hassoun PM, Girgis RE. Survival in pulmonary hypertension associated with the scleroderma spectrum of diseases: Impact of interstitial lung disease. Arthritis Rheum 60(2):569-577, 2009.
Angelini DJ, Su Q. Yamaji-Kegan K, Fan C. Teng X, Hassoun PM, Yang SC, Champion HC, Tuder RM, Johns RA. Resistin-like molecule-{beta} (RELM{beta} in scleroderma-associated pulmonary hypertension. Am J Respir Cell Mol Biol 2009 Feb 9 [Epub ahead of print].
Research Interests
- Pulmonary hypertension/Scleroderma-associated pulmonary hypertension/
More Info
Languages
- English
- French
- Arabic
Memberships
American Thoracic Society
Massachusetts Thoracic Society
American Heart Association
European Respiratory Society
Physicians for Human Rights
Fellow, American College of Chest Physicians
Maryland Thoracic Society
Massachusetts Thoracic Society
American Heart Association
European Respiratory Society
Physicians for Human Rights
Fellow, American College of Chest Physicians
Maryland Thoracic Society
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