Title(s):
Associate Professor of Otolaryngology-Head and Neck Surgery
Associate Professor of Oncology
Associate Professor of Oncology
Appointment Phone:
443-997-6467
Primary Location:
Johns Hopkins Outpatient Center
Expertise:
Head and Neck Cancers, Laryngeal Cancer, Oral Cancers, Oral Pathology, Otolaryngology, Parathyroid Surgery, Pharynx Cancer, Sinonasal Tumors, Skin Cancer of the Head and Neck, Skull Base Tumors, Thyroid Cancer, Thyroid Masses, Thyroid Surgery
Education and Experience
Training
- Johns Hopkins University School of Medicine (Baltimore MD)/ (2001)
Residencies
- The Johns Hopkins Hospital (Baltimore MD)/ Otolaryngology (2007)
Fellowships
- Memorial Sloan - Kettering Cancer Center (New York NY)/ Surgical Oncology (2008)
Certifications
- Otolaryngology, American Board of Otolaryngology (2009)
Locations
Johns Hopkins Outpatient Center
601 N. Caroline Street
Baltimore, MD 21287
Phone: 410-502-9827
Appointment Phone: 443-997-6467
Fax: 410-955-0035
Location Map
The Johns Hopkins Hospital
600 N. Wolfe Street
Hospital Main Entrance - Sheikh Zayed Tower
Baltimore, MD 21287
Phone: 410-502-9827
Appointment Phone: 443-997-6467
Fax: 410-955-0035
Location Map
Department / Division
-
Otolaryngology - Head and Neck Surgery - Division of Head and Neck Surgery
Centers/Institutes
Centers / Institutes
- Head and Neck Cancer Center
- Sidney Kimmel Comprehensive Cancer Center
- Upper Aero-digestive Tract Cancer Program
Bio
Biography
Dr. Agrawal specializes in the treatment of benign and malignant tumors of the head and neck. He has published widely, including a landmark paper on the genomic landscape of head and neck squamous cell carcinoma. In addition to the genetics of head and neck tumors, Dr. Agrawal''s research is focused on the development of biomarkers for screening, monitoring and surveillance of head and neck tumors. He serves on several committees of national organizations, including American Head and Neck Society and American Thyroid Association.
Awards and Honors
Richard Westcott Appleton Scholarship, 2000-2001
Owsei Temkin Scholarship, 1999-2001
Johns Hopkins University School of Medicine Scholarship, 1997-1999
Marvin Harold Cheiten Award (1st in Class at Rutgers College), 1997
Henry Rutgers Scholar, 1997
Betty Falk Yatvin Memorial Award, 1997
Highest Honors in Biological Sciences, 1997
Rutgers College Class of 1969 Merit Scholarship, 1996-1997
Bell Atlantic Scholarship, 1995-1996
Center for Advanced Biotechnology and Medicine Fellowship, 1995-1996
Waksman Endowment Scholarship, 1994-1995
Owsei Temkin Scholarship, 1999-2001
Johns Hopkins University School of Medicine Scholarship, 1997-1999
Marvin Harold Cheiten Award (1st in Class at Rutgers College), 1997
Henry Rutgers Scholar, 1997
Betty Falk Yatvin Memorial Award, 1997
Highest Honors in Biological Sciences, 1997
Rutgers College Class of 1969 Merit Scholarship, 1996-1997
Bell Atlantic Scholarship, 1995-1996
Center for Advanced Biotechnology and Medicine Fellowship, 1995-1996
Waksman Endowment Scholarship, 1994-1995
Expertise
- Head and Neck Cancers
- Laryngeal Cancer
- Oral Cancers
- Oral Pathology
- Otolaryngology
- Parathyroid Surgery
- Pharynx Cancer
- Sinonasal Tumors
- Skin Cancer of the Head and Neck
- Skull Base Tumors
- Thyroid Cancer
- Thyroid Masses
- Thyroid Surgery
Professional Highlights
George T Nager Award for Excellence in Teaching, 2012
Richard Westcott Appleton Scholarship, 2000-2001
Owsei Temkin Scholarship, 1999-2001
Johns Hopkins University School of Medicine Scholarship, 1997-1999
Marvin Harold Cheiten Award (1st in Class at Rutgers College), 1997
Henry Rutgers Scholar, 1997
Betty Falk Yatvin Memorial Award, 1997
Highest Honors in Biological Sciences, 1997
Rutgers College Class of 1969 Merit Scholarship, 1996-1997
Bell Atlantic Scholarship, 1995-1996
Center for Advanced Biotechnology and Medicine Fellowship, 1995-1996
Waksman Endowment Scholarship, 1994-1995
Richard Westcott Appleton Scholarship, 2000-2001
Owsei Temkin Scholarship, 1999-2001
Johns Hopkins University School of Medicine Scholarship, 1997-1999
Marvin Harold Cheiten Award (1st in Class at Rutgers College), 1997
Henry Rutgers Scholar, 1997
Betty Falk Yatvin Memorial Award, 1997
Highest Honors in Biological Sciences, 1997
Rutgers College Class of 1969 Merit Scholarship, 1996-1997
Bell Atlantic Scholarship, 1995-1996
Center for Advanced Biotechnology and Medicine Fellowship, 1995-1996
Waksman Endowment Scholarship, 1994-1995
Research
Research and Publications
Agrawal N, Frederick MJ, Pickering CR, Bettegowda C, Chang K, Li RJ, Fakhry C, Xie TX, Zhang J, Wang J, Zhang N, El-Naggar AK, Jasser SA, Weinstein JN, Trevio L, Drummond JA, Muzny DM, Wu Y, Wood LD, Hruban RH, Westra WH, Koch WM, Califano JA, Gibbs RA, Sidransky D, Vogelstein B, Velculescu VE, Papadopoulos N, Wheeler DA, Kinzler KW, Myers JN. Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1. Science. 2011; 333(6046): 1154-1157.
Bettegowda C, Agrawal N, Jiao Y, Sausen M, Wood LD, Hruban RH, Rodriguez FJ, Cahill DP, McLendon R, Riggins G, Velculescu VE, Oba-Shinjo SM, Marie SK, Vogelstein B, Bigner D, Yan H, Papadopoulos N, Kinzler KW. Mutations in CIC and FUBP1 contribute to human oligodendroglioma. Science. 2011; 333(6048): 1453-1455.
Holdhoff M, Schmidt K, Diehl F, Agrawal N, Angenendt P, Romans K, Edelstein D, Torbenson MS, Kinzler K, Vogelstein B, Choti MA, Diaz LA. Detection of tumor DNA at the margins of colorectal cancer liver metastasis. Clin Cancer Res. 2011; 17(11): 3551-3557.
Sen N, Hara MR, Ahmad AS, Cascio MB, Kamiya A, Ehmsen JT, Agrawal N, Hester L, Dore S, Synder SH, Sawa A. GOSPEL: a neuroprotective protein that binds to GAPDH upon S-nitrosylation. Neuron. 2009; 63(1): 81-91.
Diehl F, Schmidt K, Choti M, Romans K, Goodman S, Li M, Thornton K, Agrawal N, Sokoll L, Szabo SA, Kinzler KW, Vogelstein B, Diaz LA. Circulating tumor DNA to assess tumor dynamics. Nature Medicine. 2008; 14(9): 985-990.
Farrag TY, Agrawal N, Sheth S, Bettegowda C, Ewertz M, Kim M, Tufano RP. An algorithm for safe and effective re-operative thyroid bed surgery for recurrent/persistent papillary thyroid carcinoma. Head and Neck. 2007; 29(12): 1069-1074.
Bettegowda C, Foss CA, Cheong I, Wang Y, Diaz LA, Agrawal N, Fox J, Dick J, Dang LH, Zhou S, Kinzler KW, Vogelstein B, Pomper MG. Imaging bacterial infections with radiolabeled 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodouracil. PNAS. 2005; 102: 1145-1150.
Hara MR, Agrawal N, Kim SF, Cascio MB, Fujimuro M, Ozeki Y, Takahashi M, Cheah JH, Tankou SK, Hester LD, Ferris CD, Hayward SD, Snyder SH, Sawa A. S-nitrosylated glyceraldehyde-3-phosphate dehydrogenase initiates apoptotic cell death by nuclear translocation following Siah1 binding. Nature Cell Biology. 2005; 7: 665-674.
Bae BI, Xu H, Igarashi S, Fujimuro M, Agrawal N, Taya Y, Hayward SD, Moran TH, Montell C, Ross CA, Snyder SH, Sawa A. p53 mediates cellular dysfunction and behavioral abnormalities in Huntingtons disease. Neuron. 2005; 47: 29-41.
Agrawal N, Bettegowda C, Cheong I, Geschwind J, Drake CG, Hipkiss EL, Tatsumi M, Dang LH, Diaz LA, Pomper M, Abusedera M, Wahl RL, Kinzler KW, Zhou S, Huso DL, Vogelstein B. Bacteriolytic therapy can generate a potent immune response against experimental tumors. PNAS. 2004; 101: 15172-15177.
Bettegowda C, Agrawal N, Jiao Y, Sausen M, Wood LD, Hruban RH, Rodriguez FJ, Cahill DP, McLendon R, Riggins G, Velculescu VE, Oba-Shinjo SM, Marie SK, Vogelstein B, Bigner D, Yan H, Papadopoulos N, Kinzler KW. Mutations in CIC and FUBP1 contribute to human oligodendroglioma. Science. 2011; 333(6048): 1453-1455.
Holdhoff M, Schmidt K, Diehl F, Agrawal N, Angenendt P, Romans K, Edelstein D, Torbenson MS, Kinzler K, Vogelstein B, Choti MA, Diaz LA. Detection of tumor DNA at the margins of colorectal cancer liver metastasis. Clin Cancer Res. 2011; 17(11): 3551-3557.
Sen N, Hara MR, Ahmad AS, Cascio MB, Kamiya A, Ehmsen JT, Agrawal N, Hester L, Dore S, Synder SH, Sawa A. GOSPEL: a neuroprotective protein that binds to GAPDH upon S-nitrosylation. Neuron. 2009; 63(1): 81-91.
Diehl F, Schmidt K, Choti M, Romans K, Goodman S, Li M, Thornton K, Agrawal N, Sokoll L, Szabo SA, Kinzler KW, Vogelstein B, Diaz LA. Circulating tumor DNA to assess tumor dynamics. Nature Medicine. 2008; 14(9): 985-990.
Farrag TY, Agrawal N, Sheth S, Bettegowda C, Ewertz M, Kim M, Tufano RP. An algorithm for safe and effective re-operative thyroid bed surgery for recurrent/persistent papillary thyroid carcinoma. Head and Neck. 2007; 29(12): 1069-1074.
Bettegowda C, Foss CA, Cheong I, Wang Y, Diaz LA, Agrawal N, Fox J, Dick J, Dang LH, Zhou S, Kinzler KW, Vogelstein B, Pomper MG. Imaging bacterial infections with radiolabeled 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodouracil. PNAS. 2005; 102: 1145-1150.
Hara MR, Agrawal N, Kim SF, Cascio MB, Fujimuro M, Ozeki Y, Takahashi M, Cheah JH, Tankou SK, Hester LD, Ferris CD, Hayward SD, Snyder SH, Sawa A. S-nitrosylated glyceraldehyde-3-phosphate dehydrogenase initiates apoptotic cell death by nuclear translocation following Siah1 binding. Nature Cell Biology. 2005; 7: 665-674.
Bae BI, Xu H, Igarashi S, Fujimuro M, Agrawal N, Taya Y, Hayward SD, Moran TH, Montell C, Ross CA, Snyder SH, Sawa A. p53 mediates cellular dysfunction and behavioral abnormalities in Huntingtons disease. Neuron. 2005; 47: 29-41.
Agrawal N, Bettegowda C, Cheong I, Geschwind J, Drake CG, Hipkiss EL, Tatsumi M, Dang LH, Diaz LA, Pomper M, Abusedera M, Wahl RL, Kinzler KW, Zhou S, Huso DL, Vogelstein B. Bacteriolytic therapy can generate a potent immune response against experimental tumors. PNAS. 2004; 101: 15172-15177.
Research Interests
- Dr. Agrawal's research is focused on the genetics of head and neck cancer Genetics and the development of diagnostic biomarkers for screening, monitoring and surveillance of head and neck cancer.
Facebook
Twitter
Sharecare
Blogs
YouTube
RSS
Podcasts