Title(s):
Associate Professor of Urology
Associate Professor of Oncology
Associate Professor of Oncology
Assistant Professor of Pathology
Assistant Professor of Oncology
Assistant Professor of Oncology
Appointment Phone:
410-955-6100
Primary Location:
Johns Hopkins Outpatient Center
Expertise:
Bladder Cancer, Kidney Cancer, Prostate Cancer, Robotic Prostatectomy, Robotic Surgery, Urology, Urology / Urologic Surgery
Education and Experience
Training
- University of Chicago Pritzker School of Medicine (Chicago IL)/ (2001)
Residencies
- The Johns Hopkins Hospital (Baltimore MD)/ Urology (2007)
Certifications
- Urology, American Board of Urology (2009)
Locations
Johns Hopkins Outpatient Center
601 N. Caroline Street
Baltimore, MD 21287
Phone: 410-502-2733
Appointment Phone: 410-955-6100
Fax: 410-614-8487
Location Map
Department / Division
-
Urology - Urologic Oncology
Centers/Institutes
Centers / Institutes
- Brady Urological Institute
Bio
Biography
Dr. Schaeffer has an active clinical practice in urologic oncology specializing in prostate, bladder and kidney cancer. He has expertise in open, laparoscopic and robot treatment of these malignancies. As an active member of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Dr Schaeffer participates in multidisciplinary approaches to the treatment of genitourinary cancers.
Dr. Schaeffer is also a fully trained scientist and an expert in prostate development and prostate carcinogenesis. His laboratory currently investigates novel pathways of prostate and bladder carcinogenesis through utilization of experimental embryology and systems of epithelial injury repair.
Dr Schaeffer's accomplishments in both medicine and science have recently been acknowledged with several awards including the American Urological Association/Astellas "Rising Star" award and a Howard Hughes Clinician-Scientist Early Careers Award.
Dr. Schaeffer is also a fully trained scientist and an expert in prostate development and prostate carcinogenesis. His laboratory currently investigates novel pathways of prostate and bladder carcinogenesis through utilization of experimental embryology and systems of epithelial injury repair.
Dr Schaeffer's accomplishments in both medicine and science have recently been acknowledged with several awards including the American Urological Association/Astellas "Rising Star" award and a Howard Hughes Clinician-Scientist Early Careers Award.
Physician Title
Assistant Professor of Pathology
Assistant Professor of Oncology
Assistant Professor of Oncology
Expertise
- Bladder Cancer
- Kidney Cancer
- Prostate Cancer
- Robotic Prostatectomy
- Robotic Surgery
- Urology
- Urology / Urologic Surgery
Research
Research and Publications
Journal Citations
Zahurak, M.; Parmigiani, G.; Yu, W.; Scharpf, R.B.; Berman, D.; Schaeffer, E.; Shabbeer, S.; Cope, L. Pre-processing Agilent microarray data. BMC Bioinformatics. 2007;8:142.
Bivalacqua, T.J.; Guzzo, T.J.; Schaeffer, E.M.; Gebska, M.A.; Champion, H.C.; Burnett, A.L.; Gonzalgo, M.L. Application of Evicel to cavernous nerves of the rat does not influence erectile function in vivo. Urology. 2008 Nov;72(5):1169-1173.
Schaeffer, E.M.; Marchionni, L.; Huang, Z.; Simons, B.; Blackman, A.; Yu, W.; Parmigiani, G.; Berman, D.M. Androgen-induced programs for prostate epithelial growth and invasion arise in embryogenesis and are reactivated in cancer. Oncogene. 2008 Dec 4;27(57):7180-7191.
Albadine, R.; Wang, W.; Brownlee, N.A.; Toubaji, A.; Billis, A.; Argani, P.; Epstein, J.I.; Garvin, A.J.; Cousi, R.; Schaeffer, E.M.; Pavlovich, C.; Netto, G.J. Topoisomerase II alpha status in renal medullary carcinoma: immuno-expression and gene copy alterations of a potential target of therapy. J Urol. 2009 Aug;182(2):735-740.
Brandt, W.D.; Matsui, W.; Rosenberg, J.E.; He, X.; Ling, S.; Schaeffer, E.M.; Berman, D.M. Urothelial carcinoma: stem cells on the edge. Cancer Metastasis Rev. 2009 Dec;28(3-4):291-304.
Guzzo, T.J.; Allaf, M.E.; Pierorazio, P.M.; Miller, D.; McNeil, B.K.; Kavoussi, L.R.; Pavlovich, C.P.; Schaeffer, E.M. Perioperative outcomes of elderly patients undergoing laparoscopic renal procedures. Urology. 2009 Mar;73(3):572-576.
Guzzo, T.J.; Bivalacqua, T.J.; Pierorazio, P.M.; Varkarakis, J.; Schaeffer, E.M.; Allaf, M.E. Xanthogranulomatous pyelonephritis: presentation and management in the era of laparoscopy. BJU Int. 2009 Nov;104(9):1265-1268.
Guzzo, T.J.; Pierorazio, P.M.; Schaeffer, E.M.; Fishman, E.K.; Allaf, M.E. The accuracy of multidetector computerized tomography for evaluating tumor thrombus in patients with renal cell carcinoma. J Urol. 2009 Feb;181(2):486-490; discussion 491.
Guzzo, T.J.; Schaeffer, E.M.; McNeil, B.K.; Pollock, R.A.; Pavlovich, C.P.; Allaf, M.E. Laparoscopic radical nephrectomy for patients with pathologic T3b renal-cell carcinoma: the Johns Hopkins experience. Journal of endourology / Endourological Society. 2009 Jan;23(1):63-67.
Loeb, S.; Carter, H.B.; Schaeffer, E.M.; Ferrucci, L.; Kettermann, A.; Metter, E.J. Should prostate specific antigen be adjusted for body mass index? Data from the Baltimore Longitudinal Study of Aging. J Urol. 2009 Dec;182(6):2646-2651.
Loeb, S.; Schaeffer, E.M. Risk factors, prevention and early detection of prostate cancer. Primary care. 2009 Sep;36(3):603-621.
Loeb, S.; Schaeffer, E.M. Optimal therapy in localized prostate cancer: an unfolding story. Oncology (Williston Park). 2009 Sep;23(10):843, 846.
Loeb, S.; Schaeffer, E.M.; Chan, D.W.; Carter, H.B.; Walsh, P.C.; Sokoll, L.J. Investigation of human anti-mouse antibodies as potential cause of postprostatectomy PSA elevation. Urology. 2009 May;73(5):947-949.
Loeb, S.; Schaeffer, E.M.; Trock, B.J.; Epstein, J.I.; Humphreys, E.B.; Walsh, P.C. What Are the Outcomes of Radical Prostatectomy for High-risk Prostate Cancer? Urology. 2009 Nov 19.
Schaeffer, E.M.; Carter, H.B.; Kettermann, A.; Loeb, S.; Ferrucci, L.; Landis, P.; Trock, B.J.; Metter, E.J. Prostate specific antigen testing among the elderly-when to stop? J Urol. 2009 Apr;181(4):1606-1614; discussion 1613-1604.
Schaeffer, E.M.; Guzzo, T.J.; Furge, K.A.; Netto, G.; Westphal, M.; Dykema, K.; Yang, X.; Zhou, M.; Teh, B.T.; Pavlovich, C.P. Renal medullary carcinoma: molecular, pathological and clinical evidence for treatment with topoisomerase-inhibiting therapy. BJU Int. 2009 Dec 11.
Loeb, S.; Makarov, D.V.; Schaeffer, E.M.; Humphreys, E.B.; Walsh, P.C. Prostate specific antigen at the initial diagnosis of metastasis to bone in patients after radical prostatectomy. J Urol. 2010 Jul;184(1):157-161.
Loeb, S.; Partin, A.W.; Schaeffer, E.M. Complications of pelvic lymphadenectomy: do the risks outweigh the benefits? Rev Urol. 2010 Winter;12(1):20-24.
Loeb, S.; Schaeffer, E.M.; Epstein, J.I. The vanishing prostate cancer phenomenon. Urology. 2010 Sep;76(3):605-607.
Meeks, J.J.; Schaeffer, E.M. Genetic Regulation of Prostate Development. J Androl. 2010 Nov 4.
Ross, A.E.; Emadi, A.; Marchionni, L.; Hurley, P.J.; Simons, B.W.; Schaeffer, E.M.; Vuica-Ross, M. Dimeric naphthoquinones, a novel class of compounds with prostate cancer cytotoxicity. BJU Int. 2010 Dec 22.
Schaeffer, E.M.; Guzzo, T.J.; Furge, K.A.; Netto, G.; Westphal, M.; Dykema, K.; Yang, X.; Zhou, M.; Teh, B.T.; Pavlovich, C.P. Renal medullary carcinoma: molecular, pathological and clinical evidence for treatment with topoisomerase-inhibiting therapy. BJU Int. 2010 Jul;106(1):62-65.
Schaeffer, E.M.; Loeb, S.; Walsh, P.C. The case for open radical prostatectomy. Urol Clin North Am. 2010 Feb;37(1):49-55, Table of Contents.
Zahurak, M.; Parmigiani, G.; Yu, W.; Scharpf, R.B.; Berman, D.; Schaeffer, E.; Shabbeer, S.; Cope, L. Pre-processing Agilent microarray data. BMC Bioinformatics. 2007;8:142.
Bivalacqua, T.J.; Guzzo, T.J.; Schaeffer, E.M.; Gebska, M.A.; Champion, H.C.; Burnett, A.L.; Gonzalgo, M.L. Application of Evicel to cavernous nerves of the rat does not influence erectile function in vivo. Urology. 2008 Nov;72(5):1169-1173.
Schaeffer, E.M.; Marchionni, L.; Huang, Z.; Simons, B.; Blackman, A.; Yu, W.; Parmigiani, G.; Berman, D.M. Androgen-induced programs for prostate epithelial growth and invasion arise in embryogenesis and are reactivated in cancer. Oncogene. 2008 Dec 4;27(57):7180-7191.
Albadine, R.; Wang, W.; Brownlee, N.A.; Toubaji, A.; Billis, A.; Argani, P.; Epstein, J.I.; Garvin, A.J.; Cousi, R.; Schaeffer, E.M.; Pavlovich, C.; Netto, G.J. Topoisomerase II alpha status in renal medullary carcinoma: immuno-expression and gene copy alterations of a potential target of therapy. J Urol. 2009 Aug;182(2):735-740.
Brandt, W.D.; Matsui, W.; Rosenberg, J.E.; He, X.; Ling, S.; Schaeffer, E.M.; Berman, D.M. Urothelial carcinoma: stem cells on the edge. Cancer Metastasis Rev. 2009 Dec;28(3-4):291-304.
Guzzo, T.J.; Allaf, M.E.; Pierorazio, P.M.; Miller, D.; McNeil, B.K.; Kavoussi, L.R.; Pavlovich, C.P.; Schaeffer, E.M. Perioperative outcomes of elderly patients undergoing laparoscopic renal procedures. Urology. 2009 Mar;73(3):572-576.
Guzzo, T.J.; Bivalacqua, T.J.; Pierorazio, P.M.; Varkarakis, J.; Schaeffer, E.M.; Allaf, M.E. Xanthogranulomatous pyelonephritis: presentation and management in the era of laparoscopy. BJU Int. 2009 Nov;104(9):1265-1268.
Guzzo, T.J.; Pierorazio, P.M.; Schaeffer, E.M.; Fishman, E.K.; Allaf, M.E. The accuracy of multidetector computerized tomography for evaluating tumor thrombus in patients with renal cell carcinoma. J Urol. 2009 Feb;181(2):486-490; discussion 491.
Guzzo, T.J.; Schaeffer, E.M.; McNeil, B.K.; Pollock, R.A.; Pavlovich, C.P.; Allaf, M.E. Laparoscopic radical nephrectomy for patients with pathologic T3b renal-cell carcinoma: the Johns Hopkins experience. Journal of endourology / Endourological Society. 2009 Jan;23(1):63-67.
Loeb, S.; Carter, H.B.; Schaeffer, E.M.; Ferrucci, L.; Kettermann, A.; Metter, E.J. Should prostate specific antigen be adjusted for body mass index? Data from the Baltimore Longitudinal Study of Aging. J Urol. 2009 Dec;182(6):2646-2651.
Loeb, S.; Schaeffer, E.M. Risk factors, prevention and early detection of prostate cancer. Primary care. 2009 Sep;36(3):603-621.
Loeb, S.; Schaeffer, E.M. Optimal therapy in localized prostate cancer: an unfolding story. Oncology (Williston Park). 2009 Sep;23(10):843, 846.
Loeb, S.; Schaeffer, E.M.; Chan, D.W.; Carter, H.B.; Walsh, P.C.; Sokoll, L.J. Investigation of human anti-mouse antibodies as potential cause of postprostatectomy PSA elevation. Urology. 2009 May;73(5):947-949.
Loeb, S.; Schaeffer, E.M.; Trock, B.J.; Epstein, J.I.; Humphreys, E.B.; Walsh, P.C. What Are the Outcomes of Radical Prostatectomy for High-risk Prostate Cancer? Urology. 2009 Nov 19.
Schaeffer, E.M.; Carter, H.B.; Kettermann, A.; Loeb, S.; Ferrucci, L.; Landis, P.; Trock, B.J.; Metter, E.J. Prostate specific antigen testing among the elderly-when to stop? J Urol. 2009 Apr;181(4):1606-1614; discussion 1613-1604.
Schaeffer, E.M.; Guzzo, T.J.; Furge, K.A.; Netto, G.; Westphal, M.; Dykema, K.; Yang, X.; Zhou, M.; Teh, B.T.; Pavlovich, C.P. Renal medullary carcinoma: molecular, pathological and clinical evidence for treatment with topoisomerase-inhibiting therapy. BJU Int. 2009 Dec 11.
Loeb, S.; Makarov, D.V.; Schaeffer, E.M.; Humphreys, E.B.; Walsh, P.C. Prostate specific antigen at the initial diagnosis of metastasis to bone in patients after radical prostatectomy. J Urol. 2010 Jul;184(1):157-161.
Loeb, S.; Partin, A.W.; Schaeffer, E.M. Complications of pelvic lymphadenectomy: do the risks outweigh the benefits? Rev Urol. 2010 Winter;12(1):20-24.
Loeb, S.; Schaeffer, E.M.; Epstein, J.I. The vanishing prostate cancer phenomenon. Urology. 2010 Sep;76(3):605-607.
Meeks, J.J.; Schaeffer, E.M. Genetic Regulation of Prostate Development. J Androl. 2010 Nov 4.
Ross, A.E.; Emadi, A.; Marchionni, L.; Hurley, P.J.; Simons, B.W.; Schaeffer, E.M.; Vuica-Ross, M. Dimeric naphthoquinones, a novel class of compounds with prostate cancer cytotoxicity. BJU Int. 2010 Dec 22.
Schaeffer, E.M.; Guzzo, T.J.; Furge, K.A.; Netto, G.; Westphal, M.; Dykema, K.; Yang, X.; Zhou, M.; Teh, B.T.; Pavlovich, C.P. Renal medullary carcinoma: molecular, pathological and clinical evidence for treatment with topoisomerase-inhibiting therapy. BJU Int. 2010 Jul;106(1):62-65.
Schaeffer, E.M.; Loeb, S.; Walsh, P.C. The case for open radical prostatectomy. Urol Clin North Am. 2010 Feb;37(1):49-55, Table of Contents.
Research Interests
- Prostate Development
- Prostate Cancer
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Languages
- English
Memberships
American Urological Association
Clinical Trials
- Prostate Cancer
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