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Misop Han, MD

Han, Misop , MD

Misop Han, MD

Title(s):
Associate Professor of Urology
Associate Professor of Oncology

Appointment Phone:
410-955-6100

Primary Location:
The Johns Hopkins Hospital

Expertise:
Benign Prostatic Hyperplasia, Kidney Cancer, Prostate Cancer, Robotic Prostatectomy, Robotic Surgery, Urology, Urology / Urologic Surgery, Urology, Adult

Education and Experience

Training
  • Johns Hopkins University School of Medicine (Baltimore MD)/ (1996)
Residencies
  • The Johns Hopkins Hospital (Baltimore MD)/ Surgery/Urology (2002)
Certifications
  • Urology, American Board of Urology (2005)

Locations

The Johns Hopkins Hospital
600 N. Wolfe Street
Hospital Main Entrance - Sheikh Zayed Tower
Baltimore, MD 21287
Appointment Phone: 410-955-6100
Location Map
Johns Hopkins Outpatient Center
601 N. Caroline Street
Baltimore, MD 21287
Appointment Phone: 410-955-6100
Location Map
Department / Division
  • Urology - Urologic Oncology

Centers/Institutes

Centers / Institutes
  • Brady Urological Institute
  • Prostate Cancer Multidisciplinary Clinic
  • Sidney Kimmel Comprehensive Cancer Center

Bio

Expertise
  • Benign Prostatic Hyperplasia
  • Kidney Cancer
  • Prostate Cancer
  • Robotic Prostatectomy
  • Robotic Surgery
  • Urology
  • Urology / Urologic Surgery
  • Urology, Adult

Research

Research and Publications
Journal Citations

Nielsen, M.E.; Han, M.; Mangold, L.; Humphreys, E.; Walsh, P.C.; Partin, A.W.; Freedland, S.J. Black race does not independently predict adverse outcome following radical retropubic prostatectomy at a tertiary referral center. J Urol. 2006 Aug;176(2):515-519.

Veltri, R.W.; Khan, M.A.; Marlow, C.; Miller, M.C.; Mikolajczyk, S.D.; Kojima, M.; Partin, A.W.; Marks, L.S. Alterations in nuclear structure and expression of proPSA predict differences between native Japanese and Japanese-American prostate cancer. Urology. 2006 Oct;68(4):898-904.

Hernandez, D.J.; Nielsen, M.E.; Han, M.; Partin, A.W. Contemporary evaluation of the D'amico risk classification of prostate cancer. Urology. 2007 Nov;70(5):931-935.

Veltri, R.W.; Marlow, C.; Khan, M.A.; Miller, M.C.; Epstein, J.I.; Partin, A.W. Significant variations in nuclear structure occur between and within Gleason grading patterns 3, 4, and 5 determined by digital image analysis. Prostate. 2007 Aug 1;67(11):1202-1210.

Freedland, S.J.; Mavropoulos, J.; Wang, A.; Darshan, M.; Demark-Wahnefried, W.; Aronson, W.J.; Cohen, P.; Hwang, D.; Peterson, B.; Fields, T.; Pizzo, S.V.; Isaacs, W.B. Carbohydrate restriction, prostate cancer growth, and the insulin-like growth factor axis. Prostate. 2008 Jan 1;68(1):11-19.

Henry, N.L.; Giles, J.T.; Ang, D.; Mohan, M.; Dadabhoy, D.; Robarge, J.; Hayden, J.; Lemler, S.; Shahverdi, K.; Powers, P.; Li, L.; Flockhart, D.; Stearns, V.; Hayes, D.F.; Storniolo, A.M.; Clauw, D.J. Prospective characterization of musculoskeletal symptoms in early stage breast cancer patients treated with aromatase inhibitors. Breast Cancer Res Treat. 2008 Sep;111(2):365-372.

Hernandez, D.J.; Han, M.; Humphreys, E.B.; Mangold, L.A.; Taneja, S.S.; Childs, S.J.; Bartsch, G.; Partin, A.W. Predicting the outcome of prostate biopsy: comparison of a novel logistic regression-based model, the prostate cancer risk calculator, and prostate-specific antigen level alone. BJU Int. 2008 Oct 24.

Hernandez, D.J.; Nielsen, M.E.; Han, M.; Trock, B.J.; Partin, A.W.; Walsh, P.C.; Epstein, J.I. Natural history of pathologically organ-confined (pT2), Gleason score 6 or less, prostate cancer after radical prostatectomy. Urology. 2008 Jul;72(1):172-176.

Loeb, S.; Hernandez, D.J.; Mangold, L.A.; Humphreys, E.B.; Agro, M.; Walsh, P.C.; Partin, A.W.; Han, M. Progression after radical prostatectomy for men in their thirties compared to older men. BJU Int. 2008 Jun;101(12):1503-1506.

Magheli, A.; Rais-Bahrami, S.; Trock, B.J.; Humphreys, E.B.; Partin, A.W.; Han, M.; Gonzalgo, M.L. Prostate specific antigen versus prostate specific antigen density as a prognosticator of pathological characteristics and biochemical recurrence following radical prostatectomy. J Urol. 2008 May;179(5):1780-1784; discussion 1784.

Magheli, A.; Rais-Bahrami, S.; Trock, B.J.; Humphreys, E.B.; Partin, A.W.; Han, M.; Gonzalgo, M.L. Impact of body mass index on biochemical recurrence rates after radical prostatectomy: an analysis utilizing propensity score matching. Urology. 2008 Dec;72(6):1246-1251.

Trock, B.J.; Han, M.; Freedland, S.J.; Humphreys, E.B.; DeWeese, T.L.; Partin, A.W.; Walsh, P.C. Prostate cancer-specific survival following salvage radiotherapy vs observation in men with biochemical recurrence after radical prostatectomy. Jama. 2008 Jun 18;299(23):2760-2769.

Wu, I.; Nielsen, M.E.; Han, M.; Partin, A.W.; Makarov, D.V. Does laterality of positive needle biopsy in clinical T2a patients with prostate cancer affect biochemical recurrence-free survival? Urology. 2008 Dec;72(6):1219-1223.

Zhao, K.H.; Hernandez, D.J.; Han, M.; Humphreys, E.B.; Mangold, L.A.; Partin, A.W. External validation of University of California, San Francisco, Cancer of the Prostate Risk Assessment score. Urology. 2008 Aug;72(2):396-400.

Banez, L.L.; Sun, L.; Trock, B.J.; Han, M.; Partin, A.W.; Aronson, W.J.; Terris, M.K.; Presti, J.C., Jr.; Kane, C.J.; Amling, C.L.; Moul, J.W.; Freedland, S.J. Body mass index and prostate specific antigen as predictors of adverse pathology and biochemical recurrence after prostatectomy. J Urol. 2009 Aug;182(2):491-496; discussion 496-498.

Greene, K.L.; Albertsen, P.C.; Babaian, R.J.; Carter, H.B.; Gann, P.H.; Han, M.; Kuban, D.A.; Sartor, A.O.; Stanford, J.L.; Zietman, A.; Carroll, P. Prostate specific antigen best practice statement: 2009 update. J Urol. 2009 Nov;182(5):2232-2241.

Hernandez, D.J.; Han, M.; Humphreys, E.B.; Mangold, L.A.; Taneja, S.S.; Childs, S.J.; Bartsch, G.; Partin, A.W. Predicting the outcome of prostate biopsy: comparison of a novel logistic regression-based model, the prostate cancer risk calculator, and prostate-specific antigen level alone. BJU Int. 2009 Mar;103(5):609-614.

Hu, R.; Dunn, T.A.; Wei, S.; Isharwal, S.; Veltri, R.W.; Humphreys, E.; Han, M.; Partin, A.W.; Vessella, R.L.; Isaacs, W.B.; Bova, G.S.; Luo, J. Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer. Cancer Res. 2009 Jan 1;69(1):16-22.

Roberts, W.B.; Han, M. Clinical significance and treatment of biochemical recurrence after definitive therapy for localized prostate cancer. Surgical oncology. 2009 Sep;18(3):268-274.

Guzzo, T.J.; Dluzniewski, P.; Orosco, R.; Platz, E.A.; Partin, A.W.; Han, M. Prediction of mortality after radical prostatectomy by Charlson comorbidity index. Urology. 2010 Sep;76(3):553-557.

Han, M.; Kim, C.; Mozer, P.; Schafer, F.; Badaan, S.; Vigaru, B.; Tseng, K.; Petrisor, D.; Trock, B.; Stoianovici, D. Tandem-robot Assisted Laparoscopic Radical Prostatectomy to Improve the Neurovascular Bundle Visualization: A Feasibility Study. Urology. 2010 Nov 8;Epub 11/12/10.

Hudson, T.J.; Anderson, W.; Artez, A.; Barker, A.D.; Bell, C.; Bernabe, R.R.; Bhan, M.K.; Calvo, F.; Eerola, I.; Gerhard, D.S.; Guttmacher, A.; Guyer, M.; Hemsley, F.M.; Jennings, J.L.; Kerr, D.; Klatt, P.; Kolar, P.; Kusada, J.; Lane, D.P.; Laplace, F.; Youyong, L.; Nettekoven, G.; Ozenberger, B.; Peterson, J.; Rao, T.S.; Remacle, J.; Schafer, A.J.; Shibata, T.; Stratton, M.R.; Vockley, J.G.; Watanabe, K.; Yang, H.; Yuen, M.M.; Knoppers, B.M.; Bobrow, M.; Cambon-Thomsen, A.; Dressler, L.G.; Dyke, S.O.; Joly, Y.; Kato, K.; Kennedy, K.L.; Nicolas, P.; Parker, M.J.; Rial-Sebbag, E.; Romeo-Casabona, C.M.; Shaw, K.M.; Wallace, S.; Wiesner, G.L.; Zeps, N.; Lichter, P.; Biankin, A.V.; Chabannon, C.; Chin, L.; Clement, B.; de Alava, E.; Degos, F.; Ferguson, M.L.; Geary, P.; Hayes, D.N.; Johns, A.L.; Kasprzyk, A.; Nakagawa, H.; Penny, R.; Piris, M.A.; Sarin, R.; Scarpa, A.; van de Vijver, M.; Futreal, P.A.; Aburatani, H.; Bayes, M.; Botwell, D.D.; Campbell, P.J.; Estivill, X.; Grimmond, S.M.; Gut, I.; Hirst, M.; Lopez-Otin, C.; Majumder, P.; Marra, M.; McPherson, J.D.; Ning, Z.; Puente, X.S.; Ruan, Y.; Stunnenberg, H.G.; Swerdlow, H.; Velculescu, V.E.; Wilson, R.K.; Xue, H.H.; Yang, L.; Spellman, P.T.; Bader, G.D.; Boutros, P.C.; Flicek, P.; Getz, G.; Guigo, R.; Guo, G.; Haussler, D.; Heath, S.; Hubbard, T.J.; Jiang, T.; Jones, S.M.; Li, Q.; Lopez-Bigas, N.; Luo, R.; Muthuswamy, L.; Ouellette, B.F.; Pearson, J.V.; Quesada, V.; Raphael, B.J.; Sander, C.; Speed, T.P.; Stein, L.D.; Stuart, J.M.; Teague, J.W.; Totoki, Y.; Tsunoda, T.; Valencia, A.; Wheeler, D.A.; Wu, H.; Zhao, S.; Zhou, G.; Lathrop, M.; Thomas, G.; Yoshida, T.; Axton, M.; Gunter, C.; Miller, L.J.; Zhang, J.; Haider, S.A.; Wang, J.; Yung, C.K.; Cross, A.; Liang, Y.; Gnaneshan, S.; Guberman, J.; Hsu, J.; Chalmers, D.R.; Hasel, K.W.; Kaan, T.S.; Lowrance, W.W.; Masui, T.; Rodriguez, L.L.; Vergely, C.; Bowtell, D.D.; Cloonan, N.; deFazio, A.; Eshleman, J.R.; Etemadmoghadam, D.; Gardiner, B.A.; Kench, J.G.; Sutherland, R.L.; Tempero, M.A.; Waddell, N.J.; Wilson, P.J.; Gallinger, S.; Tsao, M.S.; Shaw, P.A.; Petersen, G.M.; Mukhopadhyay, D.; DePinho, R.A.; Thayer, S.; Shazand, K.; Beck, T.; Sam, M.; Timms, L.; Ballin, V.; Lu, Y.; Ji, J.; Zhang, X.; Chen, F.; Hu, X.; Yang, Q.; Tian, G.; Zhang, L.; Xing, X.; Li, X.; Zhu, Z.; Yu, Y.; Yu, J.; Tost, J.; Brennan, P.; Holcatova, I.; Zaridze, D.; Brazma, A.; Egevard, L.; Prokhortchouk, E.; Banks, R.E.; Uhlen, M.; Viksna, J.; Ponten, F.; Skryabin, K.; Birney, E.; Borg, A.; Borresen-Dale, A.L.; Caldas, C.; Foekens, J.A.; Martin, S.; Reis-Filho, J.S.; Richardson, A.L.; Sotiriou, C.; Thoms, G.; van't Veer, L.; Birnbaum, D.; Blanche, H.; Boucher, P.; Boyault, S.; Masson-Jacquemier, J.D.; Pauporte, I.; Pivot, X.; Vincent-Salomon, A.; Tabone, E.; Theillet, C.; Treilleux, I.; Bioulac-Sage, P.; Decaens, T.; Franco, D.; Gut, M.; Samuel, D.; Zucman-Rossi, J.; Eils, R.; Brors, B.; Korbel, J.O.; Korshunov, A.; Landgraf, P.; Lehrach, H.; Pfister, S.; Radlwimmer, B.; Reifenberger, G.; Taylor, M.D.; von Kalle, C.; Majumder, P.P.; Pederzoli, P.; Lawlor, R.A.; Delledonne, M.; Bardelli, A.; Gress, T.; Klimstra, D.; Zamboni, G.; Nakamura, Y.; Miyano, S.; Fujimoto, A.; Campo, E.; de Sanjose, S.; Montserrat, E.; Gonzalez-Diaz, M.; Jares, P.; Himmelbaue, H.; Bea, S.; Aparicio, S.; Easton, D.F.; Collins, F.S.; Compton, C.C.; Lander, E.S.; Burke, W.; Green, A.R.; Hamilton, S.R.; Kallioniemi, O.P.; Ley, T.J.; Liu, E.T.; Wainwright, B.J. International network of cancer genome projects. Nature. 2010 Apr 15;464(7291):993-998.

Magheli, A.; Gonzalgo, M.L.; Su, L.M.; Guzzo, T.J.; Netto, G.; Humphreys, E.B.; Han, M.; Partin, A.W.; Pavlovich, C.P. Impact of surgical technique (open vs laparoscopic vs robotic-assisted) on pathological and biochemical outcomes following radical prostatectomy: an analysis using propensity score matching. BJU Int. 2010 Nov 2.

Rosson, G.D.; Magarakis, M.; Shridharani, S.M.; Stapleton, S.M.; Jacobs, L.K.; Manahan, M.A.; Flores, J.I. A review of the surgical management of breast cancer: plastic reconstructive techniques and timing implications. Ann Surg Oncol. 2010 Jul;17(7):1890-1900.

Recent Journal Citations

Han, M, Tewari A, Lee B: Pelvic lymph node dissection during laparoscopic/robotic prostatectomy. J Urol, 2011; 185(5):1667.

Pierorazio P, Ross AE, Schaeffer EM, Epstein JI, Han M, Walsh PC, Partin AW.: A contemporary analysis of outcomes of adenocarcinoma of the prostate with seminal vesicle invasion (pT3b) after radical prostatectomy. J Urol 2011;185(5):1691-7.

Gupta A, Han M. Imaging guidance in minimally invasive prostatectomy. Urol Oncology 2011:29(3):1691-7.

Magheli A, Gonzalgo ML, Su L-M, Guzzo TJ, Netto, G, Humphreys EB, Han M, Partin AW, Pavlovich CP.: Impact of surgical technique (open vs laparoscopic vs robotic-assisted) on pathological and biochemical outcomes following radical prostatectomy: an analysis using propensity score matching. BJU Int 2011;107(12):1956-62.

Lotan TL, Gurel B, Sutcliff S, Esopi D, Liu W, Xu J, Hicks J, Park BH, Humphreys E, Partin AW, Han M, Netto GH, Isaacs WB, De Marzo AM.:PTEN protein loss by immunostaining: analytic validation and prognostic indication for a high risk surgical cohort of prostate cancer patients. Clin Cancer Res. 2011; 17(50):6563-73.

Toubaji A, Albadine R, Meeker AK, Isaacs WB, Lotan T, Haffner MC, Chaux A, Epstein JI, Han M, Walsh PC, Partin AW, De Marzo AM, Platz EA, Netto GJ.: Increased gene copy number of ERG on chromosome 21 but not TMPRESS2-ERG fusion predicts outcome in prostatic adenocarcinomas. Mod Pathol. 2011;24(11):1511-20.

Pierorazio PM, Ross AE, Han M, Epstein JI, Partin AW, Schaeffer EM.: Evolution of the clinical presentation of men undergoing radical prostatectomy for high-risk prostate cancer.: BJU Int 2012:109(7):988-93.

Mullins JK, Han M, Pierorazio PM, Partin AW, Carter HB.: Radical prostatectomy outcome in men 65 years old or older with low risk prostate cancer. J Urol, 2012;187(5):1620-5.

Chalfin H, Dinizo M, Trock BJ, Feng Z, Partin AW, Walsh PC, Humphreys E, Han M.: Implications of surgical margin status on prostate cancer-specific survival.: BJU Int. 2012 Jul 12. Doi: 10.1111/j.1464-410X.2012.11371.x.

Han M, Chang D, Kim C, Lee BJ, Zuo Y, Kim HJ, Petrisor D, Trock BJ, Partin AW, Rodriguez R, Carter HB, Allaf M, Kim J, Stoianovici.: Geometric Evaluation of Systematic Transrectal Ultrasound-Guided Prostate Biopsy. J Urol. 2012

Stoianovici D, Kim C, Schafer F, Huang C-M, Petrisor D, Han M.: Endocavity Ultrasound Probe Manipulators.: IEEE/ASME Transactions on Mechatronics. 2011; 99: 1-8.

Eifler JB, Humphreys EB, Agro M, Partin AW, Trock BJ, Han M.: Causes of Death After Radical Prostatectomy at a Large Tertiary Center. J Urol 2012; 188(3): 798-802.

Dluzniewski PJ, Wang M-H, Zheng SL, De Marzo AM, Drake CG, Fedor HL, Partin AW, Han M, Fallin MD, Xu J, Isaacs WB, Platz EA.: Variation in IL10 and Other Genes Involved in the Immune Response, Production and Detoxification of Reactive Oxygen Species, and the Repair of Oxidative DNA Damage and Risk of Prostate Cancer Recurrence. Cancer Epidemiology, Biomarkers & Prevention. 2012 Sep 25.

Eifler JB, Feng Z, Lin BM, Partin MT, Humphreys EB, Han M, Epstein JI, Walsh PC, Trock BJ, Partin AW.: An updated prostate cancer staging nomogram (Partin tables) based on cases from 2006 to 2011. BJU Int. 2012 July 26. Doi: 10.1111/j.1464-410X.2012.11324.x.

Reese AC, Pierorazio PM, Han M, Partin AW.: Contemporary Evaluation of the National Comprehensive Cancer Network Prostate Cancer Risk Classification System. Urology. 2012 Sep 18. Pii:S0090-4295(12)00862-X. doi:10.1016/j.urology.2012.07.040.

Pierorazio PM, Ross AE, Lin BM, Epstein JI, Han M, Walsh PC, Partin AW, Pavlovich CP, Schaeffer EM.: Preoperative characteristics of high-Gleason disease predictive of favourable pathological and clinical outcomes at radical prostatectomy. BJU Int. 2012 Oct;110(8): 1122-8.

Kopp RP, Han M, Partin AW, Humphreys E, Freedland SJ, Parsons JK.; Obesity and prostate enlargement in men with localized prostate cancer. BJU Int. 2011 Dec;108(11):1750-5.

Pierorazio PM, Lin BM, Mullins JK, Hyndman ME, Schaeffer EM, Han M, Partin AW, Pavlovich CP.: Preoperative characteristics of men with unfavorable high-Gleason prostate cancer at radical prostatectomy. Urol Oncol. 2011 Jun 9.

Sundi D, Jeong BC, Lee SB, Han M. Optimizing the management of high-risk, localized prostate cancer. Korean J Urol. 2012 Dec;53(12):815-20. doi: 10.4111/kju.2012.53.12.815. Epub 2012 Dec 20.

Pierorazio PM, Mullins JK, Eifler JB, Voth K, Hyams ES, Han M, Pavlovich CP, Bivalacqua TJ, Partin AW, Allaf ME, Schaeffer EM. Contemporaneous comparison of open vs minimally-invasive radical prostatectomy for high-risk prostate cancer. BJU Int. 2013 Jan 28. doi: 10.1111/j.1464-410X.2012.11757.x. [Epub ahead of print]

Greene KL, Albertsen PC, Babaian RJ, Carter HB, Gann PH, Han M, Kuban DA, Sartor AO, Stanford JL, Zietman A, Carroll P. Prostate specific antigen best practice statement: 2009 update. J Urol. 2013 Jan;189(1 Suppl):S2-S11. doi: 10.1016/j.juro.2012.11.014. PMID:23234625[PubMed - in process]

Tewari A, Han M. Commentary: Robotic radical prostatectomy is an effective approach for treating localized prostate cancer-is it technique or technician? J Urol. 2012 Dec;188(6):2212. doi: 10.1016/j.juro.2012.10.023. PMID:23141041
Research Interests
  • Urologic robotics
  • Outcomes of Radical Prostatectomy

More Info

Languages
  • English
  • Korean
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