
Title(s):
Professor of Neurology
Appointment Phone:
410-550-5624
Primary Location:
Johns Hopkins Bayview Medical Center
Expertise:
Behavioral Disorders in Dementia, Dementia, Neurology
Education and Experience
Training
- University of Pennsylvania Health System School of Medicine (Philadelphia PA)/ (1988)
Residencies
- Columbia College, Columbia University (New York NY)/ Neurology (1992)
Fellowships
- Neurological Institute of New York (New York NY)/ Research Fellow (1994)
Certifications
- Neurology, American Board of Psychiatry & Neurology (1993)
Locations
Johns Hopkins Bayview Medical Center
4940 Eastern Avenue
Lord Mason Drive, Building 301 Room Room 2100
Baltimore, MD 21224
Phone: 410-550-1045
Appointment Phone: 410-550-5624
Fax: 410-550-0539
Location Map
The Johns Hopkins Hospital
600 N. Wolfe Street
Hospital Main Entrance - Sheikh Zayed Tower
Baltimore, MD 21287
Appointment Phone: 410-955-9441
Location Map
Department / Division
-
Neurology - Neuroimmunology
Centers/Institutes
Centers / Institutes
- Johns Hopkins Memory and Alzheimer's Disease Treatment Center
Bio
Biography
Dr. Ned Sacktor focuses on general neurology with a special interest in dementia and behavioral neurology.
Dr. Ned Sacktor received his medical degree from the University of Pennsylvania School of Medicine. He then completed a residency in neurology at the Neurological Institute of New York, Columbia Presbyterian Hospital. He went on to complete a behavioral neurology fellowship at the same institution.
Dr. Ned Sacktor received his medical degree from the University of Pennsylvania School of Medicine. He then completed a residency in neurology at the Neurological Institute of New York, Columbia Presbyterian Hospital. He went on to complete a behavioral neurology fellowship at the same institution.
Awards and Honors
Honors
1984 Summa Cum Laude, Phi Beta Kappa, Harvard College
1997-1998 Maryland Neurological Society President
2004-present Neurologic AIDS Research Consortium Leadership Committee Member
2004-2005 Adult AIDS Clinical Trials Group Dementia Focus Group Chairman
2006-2007 Adult AIDS Clinical Trials Group Neurology Subcommittee Chairman
2009-present World Neurology Foundation Board of Directors, Member
1984 Summa Cum Laude, Phi Beta Kappa, Harvard College
1997-1998 Maryland Neurological Society President
2004-present Neurologic AIDS Research Consortium Leadership Committee Member
2004-2005 Adult AIDS Clinical Trials Group Dementia Focus Group Chairman
2006-2007 Adult AIDS Clinical Trials Group Neurology Subcommittee Chairman
2009-present World Neurology Foundation Board of Directors, Member
Expertise
- Behavioral Disorders in Dementia
- Dementia
- Neurology
Research
Research and Publications
Selected Peer-reviewed Publications (in chronological order)
Sacktor, N., Bacellar, H., Hoover, D.R., Nance-Sproson, T.E., Selnes, O.A., Miller, E.N., Dal Pan, G.J., Kleeberger, C., Brown, A., Saah, A., McArthur, J.C. Psychomotor slowing in HIV infection: a predictor of dementia, AIDS, and death. J Neurovirology 1996:2;404-410.
Sacktor, N. (Corresponding author). The Dana Consortium on the Therapy for HIV Dementia and Related Cognitive Disorders. A randomized, double-blind, placebo-controlled trial of deprenyl and thioctic acid in HIV associated cognitive impairment. Neurology 1998;50:645-651.
Sacktor, N.C., Lyles, R.H., Skolasky, R.L., Anderson, D.E., McArthur, J.C., McFarlane, G., Selnes, O.A., Becker, J.T., Cohen, B., Wesch, J., Miller, E.N. Combination antiretroviral therapy improves psychomotor speed performance In HIV+ homosexual men. Neurology 1999;52:1640-1647.
Sacktor, N., Schifitto, G., McDermott, M.P., Marder, K., McArthur, J.C., Kieburtz, K. Transdermal selegiline in HIV-associated cognitive impairment: a pilot, placebo-controlled study. Neurology 2000;54:233-235.
Sacktor, N., Lyles, R., Skolasky R., Kleeberger, C., Selnes, O.A., Miller, E.N., Becker, J.T., Cohen, B., McArthur, J.C., and the Multicenter AIDS Cohort Study. HIV-associated neurological disease incidence changes: Multicenter AIDS Cohort Study, 1990-1998. Neurology 2001;56:257-260.
Sacktor, N., McDermott, M.P., Marder, K., Schifitto, G., Selnes, O.A., McArthur, J.C., Stern, Y., Albert, S., Palumbo,D.,Kieburtz, K., Marcaida, J., Cohen, B., Epstein, L. HIV associated cognitive impairment before and after the advent of combination therapy. J NeuroVirology 2002;8:136-142.
Sacktor, N., Haughey, N., Cutler, R., Tamara, A., Turchan, J., Pardo, C., Vargas, D., Nath, A. Novel markers of oxidative stress in actively progressive HIV dementia. J Neuroimmunol 2004;157:176-184.
Sacktor, N., Wong, M., Nakasujja, N., Skolasky, R., Selnes, O., Musisi, S., Robertson, K., McArthur, J., Ronald, A., Katabira, E. The International HIV Dementia Scale: a new rapid screening test for HIV dementia. AIDS 2005 19;1367-1374.
Sacktor, N., Skolasky, R., Selnes, O., Watters, M., Poff, P., Shiramizu, B., Shikuma, C., Valcour, V. Neuropsychological test profile differences between young and old HIV+ individuals. J Neurovirology 2007;13:203-209.
Sacktor, N, Nakasujja, N., Robertson, K., Clifford, D. HIV-associated cognitive impairment in Sub-Saharan Africa: the potential impact of clade diversity. Nature Clinical Practice Neurology 2007 Aug;3(8) 436-443.
Sacktor, N, Nakasujja, N., Skolasky, R., Robertson, K., Musisi, S., Ronald, A., Katabira, E., Clifford, D. B. Benefits and risks of stavudine therapy for HIV associated neurological complications in Uganda. Neurology 2009;72:165-170.
Sacktor, N., Nakasujja, N., Skolasky, R., Rezapour, M., Robertson, K., Musisi, S., Katabira, E., Ronald, A., Clifford, D., Laeyendecker, O., Quinn, T. HIV subtype D is associated with dementia compared to subtype A in immunosuppressed individuals at risk for cognitive impairment in Kampala, Uganda. Clin Inf Dis 2009;49:780-786.
Mohamed, M.A., Barker, P.B., Skolasky, R.L., Moxley, R.T., Pomper, M.G., Sacktor, N.C. Decreased brain Glx levels in HIV dementia: a 3 tesla MR spectroscopy study. MRI 2010;1251-1257.
Sacktor, N., Skolasky, R.L., Cox, C., Selnes, O., Becker, J.T., Cohen, B., Martin, E., Miller, E., for the Multicenter AIDS Cohort Study (MACS). Longitudinal psychomotor speed performance in HIV+ individuals: impact of age and serostatus. J NeuroVirology 2010; 335-341.
Gandhi,N; Moxley R; Creighton,J.; Vornbrock Roosa,H; Selnes,O.; McArthur J.C.; Sacktor N. Comparison of scales to evaluate the progression of HIV-associated neurocognitive disorder. HIV Therapy 2010 4: 3:371-379.
Sacktor, N., Miyahara, S., Deng, L., Evans, S., Schifitto, G., Cohen, B.A., Paul, R., Robertson, K., Jarocki, B., Scarsi, K., Coombs, R.W., Zink, M.C., Nath, A., Smith, E., Ellis, R.J., Singer, E., Weihe, J., McCarthy, S., Hosey, L., Clifford, D.B., and the ACTG 5235 team. Minocycline treatment for HIV-associated cognitive impairment: results from a randomized trial. Neurology 2011 (in press).
Sacktor, N., Bacellar, H., Hoover, D.R., Nance-Sproson, T.E., Selnes, O.A., Miller, E.N., Dal Pan, G.J., Kleeberger, C., Brown, A., Saah, A., McArthur, J.C. Psychomotor slowing in HIV infection: a predictor of dementia, AIDS, and death. J Neurovirology 1996:2;404-410.
Sacktor, N. (Corresponding author). The Dana Consortium on the Therapy for HIV Dementia and Related Cognitive Disorders. A randomized, double-blind, placebo-controlled trial of deprenyl and thioctic acid in HIV associated cognitive impairment. Neurology 1998;50:645-651.
Sacktor, N.C., Lyles, R.H., Skolasky, R.L., Anderson, D.E., McArthur, J.C., McFarlane, G., Selnes, O.A., Becker, J.T., Cohen, B., Wesch, J., Miller, E.N. Combination antiretroviral therapy improves psychomotor speed performance In HIV+ homosexual men. Neurology 1999;52:1640-1647.
Sacktor, N., Schifitto, G., McDermott, M.P., Marder, K., McArthur, J.C., Kieburtz, K. Transdermal selegiline in HIV-associated cognitive impairment: a pilot, placebo-controlled study. Neurology 2000;54:233-235.
Sacktor, N., Lyles, R., Skolasky R., Kleeberger, C., Selnes, O.A., Miller, E.N., Becker, J.T., Cohen, B., McArthur, J.C., and the Multicenter AIDS Cohort Study. HIV-associated neurological disease incidence changes: Multicenter AIDS Cohort Study, 1990-1998. Neurology 2001;56:257-260.
Sacktor, N., McDermott, M.P., Marder, K., Schifitto, G., Selnes, O.A., McArthur, J.C., Stern, Y., Albert, S., Palumbo,D.,Kieburtz, K., Marcaida, J., Cohen, B., Epstein, L. HIV associated cognitive impairment before and after the advent of combination therapy. J NeuroVirology 2002;8:136-142.
Sacktor, N., Haughey, N., Cutler, R., Tamara, A., Turchan, J., Pardo, C., Vargas, D., Nath, A. Novel markers of oxidative stress in actively progressive HIV dementia. J Neuroimmunol 2004;157:176-184.
Sacktor, N., Wong, M., Nakasujja, N., Skolasky, R., Selnes, O., Musisi, S., Robertson, K., McArthur, J., Ronald, A., Katabira, E. The International HIV Dementia Scale: a new rapid screening test for HIV dementia. AIDS 2005 19;1367-1374.
Sacktor, N., Skolasky, R., Selnes, O., Watters, M., Poff, P., Shiramizu, B., Shikuma, C., Valcour, V. Neuropsychological test profile differences between young and old HIV+ individuals. J Neurovirology 2007;13:203-209.
Sacktor, N, Nakasujja, N., Robertson, K., Clifford, D. HIV-associated cognitive impairment in Sub-Saharan Africa: the potential impact of clade diversity. Nature Clinical Practice Neurology 2007 Aug;3(8) 436-443.
Sacktor, N, Nakasujja, N., Skolasky, R., Robertson, K., Musisi, S., Ronald, A., Katabira, E., Clifford, D. B. Benefits and risks of stavudine therapy for HIV associated neurological complications in Uganda. Neurology 2009;72:165-170.
Sacktor, N., Nakasujja, N., Skolasky, R., Rezapour, M., Robertson, K., Musisi, S., Katabira, E., Ronald, A., Clifford, D., Laeyendecker, O., Quinn, T. HIV subtype D is associated with dementia compared to subtype A in immunosuppressed individuals at risk for cognitive impairment in Kampala, Uganda. Clin Inf Dis 2009;49:780-786.
Mohamed, M.A., Barker, P.B., Skolasky, R.L., Moxley, R.T., Pomper, M.G., Sacktor, N.C. Decreased brain Glx levels in HIV dementia: a 3 tesla MR spectroscopy study. MRI 2010;1251-1257.
Sacktor, N., Skolasky, R.L., Cox, C., Selnes, O., Becker, J.T., Cohen, B., Martin, E., Miller, E., for the Multicenter AIDS Cohort Study (MACS). Longitudinal psychomotor speed performance in HIV+ individuals: impact of age and serostatus. J NeuroVirology 2010; 335-341.
Gandhi,N; Moxley R; Creighton,J.; Vornbrock Roosa,H; Selnes,O.; McArthur J.C.; Sacktor N. Comparison of scales to evaluate the progression of HIV-associated neurocognitive disorder. HIV Therapy 2010 4: 3:371-379.
Sacktor, N., Miyahara, S., Deng, L., Evans, S., Schifitto, G., Cohen, B.A., Paul, R., Robertson, K., Jarocki, B., Scarsi, K., Coombs, R.W., Zink, M.C., Nath, A., Smith, E., Ellis, R.J., Singer, E., Weihe, J., McCarthy, S., Hosey, L., Clifford, D.B., and the ACTG 5235 team. Minocycline treatment for HIV-associated cognitive impairment: results from a randomized trial. Neurology 2011 (in press).
Research Interests
- HIV associated neurocognitive disorders
More Info
Languages
- English
Memberships
American Academy of Neurology
American Neurological Association
American Neurological Association
Clinical Trials
- HIV dementia
Additional Resources


