
Title(s):
Professor of Surgery
Professor of Oncology
Professor of Oncology
Co-Director, Basic and Translational Research
Chief, Endocrine Surgery
Professor, Cellular and Molecular Medicine
Chief, Endocrine Surgery
Professor, Cellular and Molecular Medicine
Appointment Phone:
443-997-1508
Primary Location:
The Johns Hopkins Hospital
Expertise:
Adrenal Disorders, Adrenal Surgery, Cervical Lymph Node Dissection, General Surgery, Laparoscopic Adrenal Surgery, Minimally Invasive Parathyroid Surgery, Parathyroid Surgery, Surgery, Thyroid Cancer, Thyroid Surgery
Education and Experience
Training
- University of Vermont College of Medicine (Burlington VT)/ (1979)
Residencies
- Maine Medical Center (Portland ME)/ General Surgery (1988)
Fellowships
- National Cancer Institute - NIH (Bethesda MD)/ Surgical Oncology (1993)
Certifications
- Surgery, American Board of Surgery (2011)
Locations
The Johns Hopkins Hospital
600 N. Wolfe Street
Hospital Main Entrance - Sheikh Zayed Tower
Baltimore, MD 21287
Phone: 410-614-1197
Appointment Phone: 443-997-1508
Location Map
Department / Division
- Surgery
Centers/Institutes
Centers / Institutes
- Department of Surgery
- Sidney Kimmel Comprehensive Cancer Center
- Thyroid Cancer Center
Bio
Biography
Martha Zeiger is currently Chief of Endocrine Surgery and Co-director of Translational and Basic Research in the Department of Surgery at Johns Hopkins University School of Medicine as well as Professor of Surgery, Oncology, Cellular and Molecular Medicine. She received her undergraduate degree from Brown University and her medical degree from The University of Vermont College of Medicine. After serving in the United States Navy as a General Medical Officer in Hawaii she completed her General Surgical residency at Maine Medical Center in Portland, Maine. Thereafter she worked as a Commander and Attending Surgeon at the National Naval Medical Center in Bethesda, Maryland. Dr. Zeiger then completed a fellowship in Surgical Oncology, focusing on Endocrine Surgery at the National Cancer Institute (NCI) in Bethesda, Maryland. After fellowship she began her career in 1993 as an attending surgeon at Johns Hopkins where she has built a busy endocrine surgery practice, established an endocrine surgery fellowship program, and directed an NIH-funded molecular biology laboratory. Her primary research focus includes researching molecular markers associated with thyroid cancer diagnosis and prognosis.
Dr. Zeiger has also held numerous leadership positions in national medical societies, including Vice President of the American Association of Endocrine Surgeons (AAES), AAES liaison to The American Association of Clinical Endocrinology (AACE) and member of the AACE Board of Directors. She currently is on the Board of Directors of the American Thyroid Association and is the International Association of Endocrine Surgeons liaison to the U.S. chapter of the International Surgical Society. She also founded and is Dean of Endocrine Surgery University, an annual course for all endocrine surgery fellows in North America.
Dr. Zeiger has also held numerous leadership positions in national medical societies, including Vice President of the American Association of Endocrine Surgeons (AAES), AAES liaison to The American Association of Clinical Endocrinology (AACE) and member of the AACE Board of Directors. She currently is on the Board of Directors of the American Thyroid Association and is the International Association of Endocrine Surgeons liaison to the U.S. chapter of the International Surgical Society. She also founded and is Dean of Endocrine Surgery University, an annual course for all endocrine surgery fellows in North America.
Physician Title
Co-Director, Basic and Translational Research
Chief, Endocrine Surgery
Professor, Cellular and Molecular Medicine
Chief, Endocrine Surgery
Professor, Cellular and Molecular Medicine
Expertise
- Adrenal Disorders
- Adrenal Surgery
- Cervical Lymph Node Dissection
- General Surgery
- Laparoscopic Adrenal Surgery
- Minimally Invasive Parathyroid Surgery
- Parathyroid Surgery
- Surgery
- Thyroid Cancer
- Thyroid Surgery
Research
Research and Publications
Chudova D, Wilde JI, Wang ET, Wang H, Rabbee N, Egidio CM, Reynolds J, Tom E, Pagan M, Rigl CT, Friedman L, Wand CC, Lanman RB, Zeiger M, Kebebew E, Rosa, J, Fellagara G, Livolsi VA, Kennedy, GC. Molecular Classification of Thyroid Nodules Using High-Dimensionality Genomic Data. J Clin Endocrinol Metab. 2010; 95(12):5296-304.
Neychev VK, Kouniavsky G, Shiue Z, Udall DN, Somervell H, Umbricht, CB, Zeiger MA.Chasing shadows: discovering the subtleties of sestamibi scans in order to facilitate minimally invasive parathyroidectomy. World J Surg 2011 Jan; 35(1):140-6.
Wang CC, Friedman L, Kennedy GC, Wang H, Kebebew E, Steward DL, Zeiger MA, Westra W, Wang Y, Khanafshar E, Fellegara G, Rosai J, LiVolsi VA, Lanman, RB. A Large multicenter Correlation study of Thyroid Nodule Cytopathology and Histopathology. Thyroid. 2011; 21(3):243-51.
Zeiger MA, Siegelman SS, Hamrahian AH. Medical and Surgical Evaluation and Treatment of Adrenal Incidentalomas. J Clin Endocrinol Metab. 2011; 96(7):2004-15.
Kitano M, Rahbari R, Patterson EE, Xiong Y, Prasad NB, Wang Y, Zeiger MA, Kebebew, E. Expression Profiling of Difficult-to-diagnose Thyroid Histologic Subtypes Shows Distinct Expression Profiles and Identify Candidate Diagnostic microRNAs. Ann Surg Oncol. 2011; 18(12):3443-52.
Gomez NR, Kouniavsky G, Tsai HL, Somervell H, Pai SI, Tufano RP, Umbricht C, Kowalski J, Dackiw APB, Zeiger MA. Tumor Size and Presence of Calcifications on Ultrasonography are Pre-Operative Predictors of Lymph Node Metastases in Patients with Papillary Thyroid Cancer. J Surg Onc. 2011; 104(6):613-6.
Wang Y, Meeker AK, Kowalski J, Tsai HL, Somervell H, Heaphy C, Sangenario LE, Prasad N, Westra WH, Zeiger MA, Umbricht CB. Telomere Length Is Related to Alternative Splice Patterns of Telemorase in Thyroid Tumors. Am J Pathol. 2011; 179(3):1415-24.
Roy R, Kouniavsky G, Venkat R, Felger EA, Shiue Z, Schneider E, Zeiger MA. The role of Preoperative Neck Ultrasound to Assess Lymph Node in Patients with Suspicious or Indeterminate Thyroid Nodules. J Surg Onc. 2012; 105:601-5.
Venkat R, Kouniavsky G, Tufano RP, Schneider ED, Dackiw AP, Zeiger MA. Long-Term Outcomes in Patients with Primary Hyperparathyroidism who Underwent Minimally Invasive Parathyroidectomy. World J Surg. 2012; 36(1):55-60.
Roy R, Kouniavsky G, Schneider E, Allendorf JD, Chabot JA, Logerfo P, Dackiw AP, Colombani P, Zeiger MA, Lee JA. Predictive Factors of Malignancy in Pediatric Thyroid Nodules. Surgery. 2011; 150 (6):1228-33.
Prasad NB, Kowalski J, Tsai HL, Talbot K, Somervell H, Kouniavsky G, Wang Y, Dackiw AP, Westra WH, Clark DP, Libutti SK, Umbricht CB, Zeiger MA. Three-Gene Molecular Diagnostic Model for Thyroid Cancer. Thyroid. 2012; 22(3):275-84. PMID: 22280184. (Featured Article).
Arciero CA, Shiue ZS, Gat, JD, Peoples GE, Dackiw APB, Tufano RP, Libutti SK, Zeiger MA, Stojadinovic A. Preoperative Thyroid Ultrasound is Indicated in Patients Undergoing Parathyroidectomy for Primary Hyperparathyroidism. J Cancer. 2012;3:1-6.
Kitano M, Rahbari R, Patterson EE, Steinberg SM, Prasad NB, Wang Y, Zeiger MA, Kebebew E. Evaluation of Candidate Diagnostic MicroRNAs in Thyroid Fine-Needle Aspiration Biopsy Samples. Thyroid. 2012; 22(3):285-91. PMID: 22304369. (Featured Article)
Keutgen SM, Filicofi F, Crowley MJ, Wang Y, Scognamiglio T, Hoda R, Buitrago D, Cooper D, Zeiger MA, Zarnegar R, Elemento O. Fahey TJ III. A Panel of Four MicroRNAs Accurately Differentiates Malignant from Benign Indeterminate Thyroid Lesions on Fine Needle Aspiration. Clin Cancer Res. 2012 Feb 20. [Epub ahead of print]PMID: 22351693.
Alexander, DK, Kennedy GC, Baloch ZW, Cibus ES, Chudova D, Diggans J, Friedman L, Kloos RT, LiVolsi VA, Mandel SJ, Raab SS, Rosai J, Steward DL, Walsh PS, Wilde JI, Zeiger MA, Lanman RB, Haugen BR. Preoperative Diagnosis of Benign Thyroid Nodules with Indeterminate Cytology. N Engl J Med. 2012.
Neychev VK, Kouniavsky G, Shiue Z, Udall DN, Somervell H, Umbricht, CB, Zeiger MA.Chasing shadows: discovering the subtleties of sestamibi scans in order to facilitate minimally invasive parathyroidectomy. World J Surg 2011 Jan; 35(1):140-6.
Wang CC, Friedman L, Kennedy GC, Wang H, Kebebew E, Steward DL, Zeiger MA, Westra W, Wang Y, Khanafshar E, Fellegara G, Rosai J, LiVolsi VA, Lanman, RB. A Large multicenter Correlation study of Thyroid Nodule Cytopathology and Histopathology. Thyroid. 2011; 21(3):243-51.
Zeiger MA, Siegelman SS, Hamrahian AH. Medical and Surgical Evaluation and Treatment of Adrenal Incidentalomas. J Clin Endocrinol Metab. 2011; 96(7):2004-15.
Kitano M, Rahbari R, Patterson EE, Xiong Y, Prasad NB, Wang Y, Zeiger MA, Kebebew, E. Expression Profiling of Difficult-to-diagnose Thyroid Histologic Subtypes Shows Distinct Expression Profiles and Identify Candidate Diagnostic microRNAs. Ann Surg Oncol. 2011; 18(12):3443-52.
Gomez NR, Kouniavsky G, Tsai HL, Somervell H, Pai SI, Tufano RP, Umbricht C, Kowalski J, Dackiw APB, Zeiger MA. Tumor Size and Presence of Calcifications on Ultrasonography are Pre-Operative Predictors of Lymph Node Metastases in Patients with Papillary Thyroid Cancer. J Surg Onc. 2011; 104(6):613-6.
Wang Y, Meeker AK, Kowalski J, Tsai HL, Somervell H, Heaphy C, Sangenario LE, Prasad N, Westra WH, Zeiger MA, Umbricht CB. Telomere Length Is Related to Alternative Splice Patterns of Telemorase in Thyroid Tumors. Am J Pathol. 2011; 179(3):1415-24.
Roy R, Kouniavsky G, Venkat R, Felger EA, Shiue Z, Schneider E, Zeiger MA. The role of Preoperative Neck Ultrasound to Assess Lymph Node in Patients with Suspicious or Indeterminate Thyroid Nodules. J Surg Onc. 2012; 105:601-5.
Venkat R, Kouniavsky G, Tufano RP, Schneider ED, Dackiw AP, Zeiger MA. Long-Term Outcomes in Patients with Primary Hyperparathyroidism who Underwent Minimally Invasive Parathyroidectomy. World J Surg. 2012; 36(1):55-60.
Roy R, Kouniavsky G, Schneider E, Allendorf JD, Chabot JA, Logerfo P, Dackiw AP, Colombani P, Zeiger MA, Lee JA. Predictive Factors of Malignancy in Pediatric Thyroid Nodules. Surgery. 2011; 150 (6):1228-33.
Prasad NB, Kowalski J, Tsai HL, Talbot K, Somervell H, Kouniavsky G, Wang Y, Dackiw AP, Westra WH, Clark DP, Libutti SK, Umbricht CB, Zeiger MA. Three-Gene Molecular Diagnostic Model for Thyroid Cancer. Thyroid. 2012; 22(3):275-84. PMID: 22280184. (Featured Article).
Arciero CA, Shiue ZS, Gat, JD, Peoples GE, Dackiw APB, Tufano RP, Libutti SK, Zeiger MA, Stojadinovic A. Preoperative Thyroid Ultrasound is Indicated in Patients Undergoing Parathyroidectomy for Primary Hyperparathyroidism. J Cancer. 2012;3:1-6.
Kitano M, Rahbari R, Patterson EE, Steinberg SM, Prasad NB, Wang Y, Zeiger MA, Kebebew E. Evaluation of Candidate Diagnostic MicroRNAs in Thyroid Fine-Needle Aspiration Biopsy Samples. Thyroid. 2012; 22(3):285-91. PMID: 22304369. (Featured Article)
Keutgen SM, Filicofi F, Crowley MJ, Wang Y, Scognamiglio T, Hoda R, Buitrago D, Cooper D, Zeiger MA, Zarnegar R, Elemento O. Fahey TJ III. A Panel of Four MicroRNAs Accurately Differentiates Malignant from Benign Indeterminate Thyroid Lesions on Fine Needle Aspiration. Clin Cancer Res. 2012 Feb 20. [Epub ahead of print]PMID: 22351693.
Alexander, DK, Kennedy GC, Baloch ZW, Cibus ES, Chudova D, Diggans J, Friedman L, Kloos RT, LiVolsi VA, Mandel SJ, Raab SS, Rosai J, Steward DL, Walsh PS, Wilde JI, Zeiger MA, Lanman RB, Haugen BR. Preoperative Diagnosis of Benign Thyroid Nodules with Indeterminate Cytology. N Engl J Med. 2012.
Research Interests
- Molecular markers to distinguish benign from malignant thyroid neoplasms
- Signal transduction pathway abnormalities associated with thyroid malignancy
More Info
Languages
- English
Memberships
American Association of Endocrine Surgeons
American Thyroid Association
American Association of Clinical Endocrinology
Fellow of the American College of Surgeons
American Thyroid Association
American Association of Clinical Endocrinology
Fellow of the American College of Surgeons
Additional Resources


