Title(s):
Professor of Psychiatry and Behavioral Sciences
Chairman of Psychiatry and Behavioral Sciences
Director of Department of Psychiatry and Behavioral Sciences
Director of Department of Psychiatry and Behavioral Sciences
Appointment Phone:
410-955-5212
Primary Location:
The Johns Hopkins Hospital
Expertise:
Affective Disorders, Bipolar Disorder, Depression, Psychiatry
Education and Experience
Training
- Johns Hopkins University School of Medicine (Baltimore MD)/ (1972)
Residencies
- The Johns Hopkins Hospital (Baltimore MD)/ Psychiatry (1977)
- Johns Hopkins Bayview Medical Center (Baltimore MD)/ Psychiatry (1974)
Certifications
- Psychiatry, American Board of Psychiatry & Neurology (1977)
Locations
The Johns Hopkins Hospital
600 N. Wolfe Street
Hospital Main Entrance - Sheikh Zayed Tower
Baltimore, MD 21287
Phone: 410-955-3130
Appointment Phone: 410-955-5212
Location Map
Department / Division
- Psychiatry and Behavioral Sciences
Centers/Institutes
Centers / Institutes
- National Network of Depression Centers
Bio
Biography
J. Raymond DePaulo, Jr., MD, is the Psychiatrist-in-Chief at the Johns Hopkins Hopspital and is also one of the world's foremost investigators into the genetic bases of bipolar disorders. He was named the Henry Phipps Professor and Chairman of the Department of Psychiatry and Behavioral Sciences in 2002. As a faculty member in the Department of Psychiatry since 1977, Dr. DePaulo has been an active clinician, teacher, and researcher.
Dr. DePaulo remains an active and sought after clinician. His commitment to teaching and mentoring reflects his optimistic vision of the future of psychiatric research.
His ongoing research includes genetic studies of bipolar disease and unipolar disorder, and combined brain imaging and genetic studies of bipolar families.
In addition to his numerous awards for research, Dr. DePaulo was invited to address the World Economics Forum in Davos, Switzerland, both in 2000 and 2001, about the burden of psychiatric disease on national and global economies.
The author of more then 100 scientific publications, Dr. DePaulo has also co-authored two books written for the general public: How to Cope with Depression and Understanding Depression.
Dr. DePaulo remains an active and sought after clinician. His commitment to teaching and mentoring reflects his optimistic vision of the future of psychiatric research.
His ongoing research includes genetic studies of bipolar disease and unipolar disorder, and combined brain imaging and genetic studies of bipolar families.
In addition to his numerous awards for research, Dr. DePaulo was invited to address the World Economics Forum in Davos, Switzerland, both in 2000 and 2001, about the burden of psychiatric disease on national and global economies.
The author of more then 100 scientific publications, Dr. DePaulo has also co-authored two books written for the general public: How to Cope with Depression and Understanding Depression.
Physician Title
Chairman of Psychiatry and Behavioral Sciences
Director of Department of Psychiatry and Behavioral Sciences
Director of Department of Psychiatry and Behavioral Sciences
Awards and Honors
1989 The 1989 Award for Outstanding New Research,
National Depressive and Manic Depressive Association
1991 Alpha Omega Alpha (elected alumnus chapter)
1992 The 1992 NIMH - D/ART, Public Education Award
1995 Harriett and Milton Parker Lecture in Psychiatric Genetics, Ohio State University
1996 SELO Prize, for outstanding research on depression, National Association for Research in Schizophrenia and Depression (NARSAD)
2002 Samuel Guze Lecture, Washington University
2007 Research Award from the American Foundation for Suicide Prevention
National Depressive and Manic Depressive Association
1991 Alpha Omega Alpha (elected alumnus chapter)
1992 The 1992 NIMH - D/ART, Public Education Award
1995 Harriett and Milton Parker Lecture in Psychiatric Genetics, Ohio State University
1996 SELO Prize, for outstanding research on depression, National Association for Research in Schizophrenia and Depression (NARSAD)
2002 Samuel Guze Lecture, Washington University
2007 Research Award from the American Foundation for Suicide Prevention
Expertise
- Affective Disorders
- Bipolar Disorder
- Depression
- Psychiatry
Research
Research and Publications
Nwulia EA, Miao K, Zandi PP, Mackinnon DF, DePaulo JR, McInnis MG. Genome-wide scan of bipolar II disorder. Bipolar Disord. 6: 580-8, 2007.
Verma R, Cutler DJ, Holmans P, Knowles JA, Crowe RR, Scheftner WA, Weissman MM, DePaulo JR Jr, Levinson DF, Potash JB. Investigating the role of p11 (S100A10) sequence variation in susceptibility to major depression. American Journal of Medical Genetics (Neuropsychiatric Genetics) 144:1079-82, 2007.
Potash JB, Buervenich S, Cox NJ, Zandi PP, Akula N, Steele J, Rathe JA, Avramopoulos D, Detera-Wadleigh SD, Gershon ES, DePaulo JR Jr, Feinberg AP, McMahon FJ; NIMH Genetics Initiative Bipolar Disorder Consortium. Gene-based SNP mapping of a psychotic bipolar affective disorder linkage region on 22q12.3: association with HMG2L1 and TOM1. American Journal of Medical Genetics (Neuropsychiatric Genetics). 147: 59-67, 2008.
Willour VL, Chen H, Toolan J, Belmonte P, Cutler DJ, Goes FS, Zandi PP, Lee RS, Mackinnon DF, Mondimore FM, Schweizer B, Depaulo JR Jr, Gershon ES, McMahon FJ, Potash JB. Family-based association of FKBP5 in bipolar disorder. Mol Psychiatry. 14: 261268, 2009.
Payne JL, MacKinnon DF, Mondimore FM, McInnis MG, Schweizer B, Zamoiski RB, McMahon FJ, Nurnberger JI Jr, Rice JP, Scheftner W, Coryell W, Berrettini WH, Kelsoe JR, Byerley W, Gershon ES, DePaulo JR, Potash JB. Familial aggregation of postpartum mood symptoms in bipolar disorder pedigrees. Bipolar Disord. 10: 38-44,2008.
Verma R, Holmans P, Knowles JA, Grover D, Evgrafov OV, Crowe RR, Scheftner WA, Weissman MM, Depaulo JR Jr, Potash JB, Levinson DF. Linkage Disequilibrium Mapping of a Chromosome 15q25-26 Major Depression Linkage Region and Sequencing of NTRK3. Biological Psychiatry. 63:1185-9, 2008.
Langlieb AM, DePaulo JR, Etiology of depression and implications on work environment. Journal of Occupational Environmental Medicine. 391-5, 2008.
Barton CD, DePaulo JR, The unrecognized costs of delirium. Nature Clinical Practice Neurology. 4:233, 2008. [Editorial]
Zandi PP, Belmonte PL, Willour VL, Goes FS, Badner JA, Simpson SG, Gershon ES, McMahon FJ, DePaulo JR
Potash JB; Association study of Wnt signaling pathway genes in bipolar disorder. Bipolar Disorder Phenome Group; National Institute of Mental Health Genetics Initiative Bipolar Disorder Consortium. Archives of General Psychiatry. 65: 785-93, 2008.
Nwulia EA, Zandi PP, McInnis MG, DePaulo JR, MacKinnon DF. Rapid switching of mood in families with familial bipolar disorder. Bipolar Disord. 10: 597-606, 2008.
Payne JL, Klein SR, Zamoiski RB, Zandi PP, Bienvenu OJ, Mackinnon DF, Mondimore FM, Schweizer B, Swartz KL; Premenstrual mood symptoms: study of familiality and personality correlates in mood disorder pedigrees. NIMH Genetics Initiative Bipolar Disorder Consortium, Crowe RP, Scheftner WA, Weissman MM, Levinson DF, DePaulo JR, Potash JB. Archives of Womens Mental Health.12: 27-34, 2009
Verma R, Cutler DJ, Holmans P, Knowles JA, Crowe RR, Scheftner WA, Weissman MM, DePaulo JR Jr, Levinson DF, Potash JB. Investigating the role of p11 (S100A10) sequence variation in susceptibility to major depression. American Journal of Medical Genetics (Neuropsychiatric Genetics) 144:1079-82, 2007.
Potash JB, Buervenich S, Cox NJ, Zandi PP, Akula N, Steele J, Rathe JA, Avramopoulos D, Detera-Wadleigh SD, Gershon ES, DePaulo JR Jr, Feinberg AP, McMahon FJ; NIMH Genetics Initiative Bipolar Disorder Consortium. Gene-based SNP mapping of a psychotic bipolar affective disorder linkage region on 22q12.3: association with HMG2L1 and TOM1. American Journal of Medical Genetics (Neuropsychiatric Genetics). 147: 59-67, 2008.
Willour VL, Chen H, Toolan J, Belmonte P, Cutler DJ, Goes FS, Zandi PP, Lee RS, Mackinnon DF, Mondimore FM, Schweizer B, Depaulo JR Jr, Gershon ES, McMahon FJ, Potash JB. Family-based association of FKBP5 in bipolar disorder. Mol Psychiatry. 14: 261268, 2009.
Payne JL, MacKinnon DF, Mondimore FM, McInnis MG, Schweizer B, Zamoiski RB, McMahon FJ, Nurnberger JI Jr, Rice JP, Scheftner W, Coryell W, Berrettini WH, Kelsoe JR, Byerley W, Gershon ES, DePaulo JR, Potash JB. Familial aggregation of postpartum mood symptoms in bipolar disorder pedigrees. Bipolar Disord. 10: 38-44,2008.
Verma R, Holmans P, Knowles JA, Grover D, Evgrafov OV, Crowe RR, Scheftner WA, Weissman MM, Depaulo JR Jr, Potash JB, Levinson DF. Linkage Disequilibrium Mapping of a Chromosome 15q25-26 Major Depression Linkage Region and Sequencing of NTRK3. Biological Psychiatry. 63:1185-9, 2008.
Langlieb AM, DePaulo JR, Etiology of depression and implications on work environment. Journal of Occupational Environmental Medicine. 391-5, 2008.
Barton CD, DePaulo JR, The unrecognized costs of delirium. Nature Clinical Practice Neurology. 4:233, 2008. [Editorial]
Zandi PP, Belmonte PL, Willour VL, Goes FS, Badner JA, Simpson SG, Gershon ES, McMahon FJ, DePaulo JR
Potash JB; Association study of Wnt signaling pathway genes in bipolar disorder. Bipolar Disorder Phenome Group; National Institute of Mental Health Genetics Initiative Bipolar Disorder Consortium. Archives of General Psychiatry. 65: 785-93, 2008.
Nwulia EA, Zandi PP, McInnis MG, DePaulo JR, MacKinnon DF. Rapid switching of mood in families with familial bipolar disorder. Bipolar Disord. 10: 597-606, 2008.
Payne JL, Klein SR, Zamoiski RB, Zandi PP, Bienvenu OJ, Mackinnon DF, Mondimore FM, Schweizer B, Swartz KL; Premenstrual mood symptoms: study of familiality and personality correlates in mood disorder pedigrees. NIMH Genetics Initiative Bipolar Disorder Consortium, Crowe RP, Scheftner WA, Weissman MM, Levinson DF, DePaulo JR, Potash JB. Archives of Womens Mental Health.12: 27-34, 2009
Research Interests
- Bipolar Disorders, Depression
More Info
Languages
- English
Memberships
Dr. DePaulo serves on the Scientific Advisory Boards of NARSAD (the National Association for Research in Schizophrenia and Depression), the American Foundation for Suicide Prevention (AFSP), and the Depression and Bipolar Support Association (DBSA).
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