Title(s):
Professor of Medicine
Professor of Oncology
Professor of Pathology
Professor of Oncology
Professor of Pathology
Appointment Phone:
410-933-7495
Primary Location:
The Johns Hopkins Hospital
Expertise:
Clinical Gastroenterology, Colon Cancer, Colon Polyps, Digestive Diseases, Family History of Cancer, Gastroenterology, Gastrointestinal Cancers, Rectal Bleeding
Education and Experience
Training
- Tufts University School of Medicine (Boston MA)/ (1980)
Fellowships
- The Johns Hopkins Hospital (Baltimore MD)/ Sr Clinical Fellow / Gastroenterology (1986)
- The Johns Hopkins Hospital (Baltimore MD)/ Gastroenterology (1985)
Certifications
- Gastroenterology, American Board of Internal Medicine (1985)
- Internal Medicine, American Board of Internal Medicine (1983)
Locations
The Johns Hopkins Hospital
600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287
Phone: 410-933-7495
Appointment Phone: 410-933-7495
Location Map
The Johns Hopkins Hospital
600 N. Wolfe Street
Hospital Main Entrance - Sheikh Zayed Tower
Baltimore, MD 21287
Phone: 410-583-2888
Appointment Phone: 410-583-2888
Location Map
Department / Division
-
Medicine - Gastroenterology and Hepatology
Centers/Institutes
Centers / Institutes
- Sidney Kimmel Comprehensive Cancer Center
Bio
Biography
Dr. Giardiello was graduated from Tufts University School of Medicine and has a MBA from Johns Hopkins University. He received his internal medicine training at The University of Michigan and fellowship training in Gastroenterology at The Johns Hopkins Hospital. Presently, he is the Johns G. Rangos, Sr. Professor of Medicine, the program director for the gastrointestinal fellowship and directs the Johns Hopkins Colorectal Cancer Registry and Risk Assessment Clinic. He served for 9 years as the Director of the Division of Gastroenterology at Johns Hopkins University.
Dr. Giardiellos clinical and research interests have focused on the study of cancer and cancer chemoprevention in the gastrointestinal tract. This has included the investigation of the genetic basis of familial colorectal cancer and the use of genetic testing in the hereditary forms of colorectal cancer. He has a continuing interest in the study of the genotypic phenotypic correlations in the polyposis syndromes which include familial adenomatous polyposis, juvenile polyposis and Peutz-Jeghers syndrome.
Dr. Giardiellos clinical and research interests have focused on the study of cancer and cancer chemoprevention in the gastrointestinal tract. This has included the investigation of the genetic basis of familial colorectal cancer and the use of genetic testing in the hereditary forms of colorectal cancer. He has a continuing interest in the study of the genotypic phenotypic correlations in the polyposis syndromes which include familial adenomatous polyposis, juvenile polyposis and Peutz-Jeghers syndrome.
Expertise
- Clinical Gastroenterology
- Colon Cancer
- Colon Polyps
- Digestive Diseases
- Family History of Cancer
- Gastroenterology
- Gastrointestinal Cancers
- Rectal Bleeding
Research
Research and Publications
Canto, M.I.; Goggins, M.; Hruban, R.H.; Petersen, G.M.; Giardiello, F.M.; Yeo, C.; Fishman, E.K.; Brune, K.; Axilbund, J.; Griffin, C.; Ali, S.; Richman, J.; Jagannath, S.; Kantsevoy, S.V.; Kalloo, A.N. Screening for early pancreatic neoplasia in high-risk individuals: a prospective controlled study. Clin Gastroenterol Hepatol. 2006 Jun;4(6):766-781; quiz 665.
Chen, S.; Wang, W.; Lee, S.; Nafa, K.; Lee, J.; Romans, K.; Watson, P.; Gruber, S.B.; Euhus, D.; Kinzler, K.W.; Jass, J.; Gallinger, S.; Lindor, N.M.; Casey, G.; Ellis, N.; Giardiello, F.M.; Offit, K.; Parmigiani, G. Prediction of germline mutations and cancer risk in the Lynch syndrome. Jama. 2006 Sep 27;296(12):1479-1487.
Hearle, N.; Schumacher, V.; Menko, F.H.; Olschwang, S.; Boardman, L.A.; Gille, J.J.; Keller, J.J.; Westerman, A.M.; Scott, R.J.; Lim, W.; Trimbath, J.D.; Giardiello, F.M.; Gruber, S.B.; Offerhaus, G.J.; Rooij, F.W.; Wilson, J.H.; Hansmann, A.; Moslein, G.; Royer-Pokora, B.; Vogel, T.; Phillips, R.K.; Spigelman, A.D.; Houlston, R.S. STK11 status and intussusception risk in Peutz-Jeghers syndrome. Journal of medical genetics. 2006 Aug;43(8):e41.
Levin, B.; Barthel, J.S.; Burt, R.W.; David, D.S.; Ford, J.M.; Giardiello, F.M.; Gruber, S.B.; Halverson, A.L.; Hamilton, S.; Kohlmann, W.; Ludwig, K.A.; Lynch, P.M.; Marino, C.; Martin, E.W., Jr.; Mayer, R.J.; Pasche, B.; Pirruccello, S.J.; Rajput, A.; Rao, M.S.; Shike, M.; Steinbach, G.; Terdiman, J.P.; Weinberg, D.; Winawer, S.J. Colorectal Cancer Screening Clinical Practice Guidelines. J Natl Compr Canc Netw. 2006 Apr;4(4):384-420.
Brim, H.; Mokarram, P.; Naghibalhossaini, F.; Saberi-Firoozi, M.; Al-Mandhari, M.; Al-Mawaly, K.; Al-Mjeni, R.; Al-Sayegh, A.; Raeburn, S.; Lee, E.; Giardiello, F.; Smoot, D.T.; Vilkin, A.; Boland, C.R.; Goel, A.; Hafezi, M.; Nouraie, M.; Ashktorab, H. Impact of BRAF, MLH1 on the incidence of microsatellite instability high colorectal cancer in populations based study. Mol Cancer. 2008;7:68.
Cho, N.L.; Redston, M.; Zauber, A.G.; Carothers, A.M.; Hornick, J.; Wilton, A.; Sontag, S.; Nishioka, N.; Giardiello, F.M.; Saltzman, J.R.; Gostout, C.; Eagle, C.J.; Hawk, E.T.; Bertagnolli, M.M. Aberrant crypt foci in the adenoma prevention with celecoxib trial. Cancer prevention research (Philadelphia, Pa. 2008 Jun;1(1):21-31.
Cruz-Correa, M.; Zhao, R.; Oviedo, M.; Bernabe, R.D.; Lacourt, M.; Cardona, A.; Lopez-Enriquez, R.; Wexner, S.; Cuffari, C.; Hylind, L.; Platz, E.; Cui, H.; Feinberg, A.P.; Giardiello, F.M. Temporal stability and age-related prevalence of loss of imprinting of the insulin-like growth factor-2 gene. Epigenetics. 2009 Feb;4(2):114-118.
Edelstein, D.L.; Axilbund, J.; Baxter, M.; Hylind, L.M.; Romans, K.; Griffin, C.A.; Cruz-Correa, M.; Giardiello, F.M. Rapid Development of Colorectal Neoplasia in Patients With Lynch Syndrome. Clin Gastroenterol Hepatol. 2010 Nov 9.
Langeveld, D.; van Hattem, W.A.; de Leng, W.W.; Morsink, F.H.; Ten Kate, F.J.; Giardiello, F.M.; Offerhaus, G.J.; Brosens, L.A. SMAD4 immunohistochemistry reflects genetic status in juvenile polyposis syndrome. Clin Cancer Res. 2010 Aug 15;16(16):4126-4134.
Chen, S.; Wang, W.; Lee, S.; Nafa, K.; Lee, J.; Romans, K.; Watson, P.; Gruber, S.B.; Euhus, D.; Kinzler, K.W.; Jass, J.; Gallinger, S.; Lindor, N.M.; Casey, G.; Ellis, N.; Giardiello, F.M.; Offit, K.; Parmigiani, G. Prediction of germline mutations and cancer risk in the Lynch syndrome. Jama. 2006 Sep 27;296(12):1479-1487.
Hearle, N.; Schumacher, V.; Menko, F.H.; Olschwang, S.; Boardman, L.A.; Gille, J.J.; Keller, J.J.; Westerman, A.M.; Scott, R.J.; Lim, W.; Trimbath, J.D.; Giardiello, F.M.; Gruber, S.B.; Offerhaus, G.J.; Rooij, F.W.; Wilson, J.H.; Hansmann, A.; Moslein, G.; Royer-Pokora, B.; Vogel, T.; Phillips, R.K.; Spigelman, A.D.; Houlston, R.S. STK11 status and intussusception risk in Peutz-Jeghers syndrome. Journal of medical genetics. 2006 Aug;43(8):e41.
Levin, B.; Barthel, J.S.; Burt, R.W.; David, D.S.; Ford, J.M.; Giardiello, F.M.; Gruber, S.B.; Halverson, A.L.; Hamilton, S.; Kohlmann, W.; Ludwig, K.A.; Lynch, P.M.; Marino, C.; Martin, E.W., Jr.; Mayer, R.J.; Pasche, B.; Pirruccello, S.J.; Rajput, A.; Rao, M.S.; Shike, M.; Steinbach, G.; Terdiman, J.P.; Weinberg, D.; Winawer, S.J. Colorectal Cancer Screening Clinical Practice Guidelines. J Natl Compr Canc Netw. 2006 Apr;4(4):384-420.
Brim, H.; Mokarram, P.; Naghibalhossaini, F.; Saberi-Firoozi, M.; Al-Mandhari, M.; Al-Mawaly, K.; Al-Mjeni, R.; Al-Sayegh, A.; Raeburn, S.; Lee, E.; Giardiello, F.; Smoot, D.T.; Vilkin, A.; Boland, C.R.; Goel, A.; Hafezi, M.; Nouraie, M.; Ashktorab, H. Impact of BRAF, MLH1 on the incidence of microsatellite instability high colorectal cancer in populations based study. Mol Cancer. 2008;7:68.
Cho, N.L.; Redston, M.; Zauber, A.G.; Carothers, A.M.; Hornick, J.; Wilton, A.; Sontag, S.; Nishioka, N.; Giardiello, F.M.; Saltzman, J.R.; Gostout, C.; Eagle, C.J.; Hawk, E.T.; Bertagnolli, M.M. Aberrant crypt foci in the adenoma prevention with celecoxib trial. Cancer prevention research (Philadelphia, Pa. 2008 Jun;1(1):21-31.
Cruz-Correa, M.; Zhao, R.; Oviedo, M.; Bernabe, R.D.; Lacourt, M.; Cardona, A.; Lopez-Enriquez, R.; Wexner, S.; Cuffari, C.; Hylind, L.; Platz, E.; Cui, H.; Feinberg, A.P.; Giardiello, F.M. Temporal stability and age-related prevalence of loss of imprinting of the insulin-like growth factor-2 gene. Epigenetics. 2009 Feb;4(2):114-118.
Edelstein, D.L.; Axilbund, J.; Baxter, M.; Hylind, L.M.; Romans, K.; Griffin, C.A.; Cruz-Correa, M.; Giardiello, F.M. Rapid Development of Colorectal Neoplasia in Patients With Lynch Syndrome. Clin Gastroenterol Hepatol. 2010 Nov 9.
Langeveld, D.; van Hattem, W.A.; de Leng, W.W.; Morsink, F.H.; Ten Kate, F.J.; Giardiello, F.M.; Offerhaus, G.J.; Brosens, L.A. SMAD4 immunohistochemistry reflects genetic status in juvenile polyposis syndrome. Clin Cancer Res. 2010 Aug 15;16(16):4126-4134.
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- English
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