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Diabetes Research Center

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Integrated Physiology

Analytical Subcore


Andrew Wolfe, Ph.D.

Multiplex Assay Detection Systems

(Luminex platform, BioTek platform)

Comprehensive Laboratory Animal Monitoring System (CLAMS)

Food intake
Paired feeding

Locomotion, circadian activity
Resting energy expenditure
Oxygen consumption
Carbon dioxide production
Heat generation

Training in CLAMS and investigator-directed CLAMS
Full-service CLAMS protocols are available as an independent service.

Body Composition


In Vivo Dynamic Physiology Subcore


Sheng Bi, M.D., M.M.

Associate Director

Timothy Moran, Ph.D.

Dynamic Physiologic Testing

Expertise, training and advice in:

Intraperitonal glucose tolerance test
Oral gavage
Oral glucose tolerance test
Insulin tolerance test
Pyruvate conversion test
Insulin secretion test

Tracer-Based In Vivo Substrate Handling
Euglycemic Clamp in Rodents
Optogentic Selective Neuronal Stimulation