Scientist: Research Projects: Mutant Mice Being Characterized

Availability of mutant mice to the public scientific community:

The information contained on this page was last updated in June 2004. No corrections or additions will be made to this site from that date forward. For more current information on the mutations listed here, as well as many newer mutations and deviants, please refer to the New Models page of The Jackson Laboratory's Craniofacial Resource website found at www.jax.org/cranio/new.html. Questions and requests should be addressed to faces@jax.org.

All of the strains on this page are now being offered to members of the scientific community who are interested in craniofacial abnormalities. Living colonies will be available during the dates posted for each mutant strain. Many colonies will be available after that time via recovery from cryopreserved sperm. When an investigator expresses interest in a particular mutant, 2 breeder pairs will be provided as soon as possible, but the breeding colony will be maintained only during the 2-month time period. If additional mice were needed after that time, they would have to be recovered from cryopreserved sperm for a fee to the Cryopreservation Resource. Photographs of mutants will remain on the public side indefinitely, even if taken by an investigator, or taken off the shelf. No indication will be made as to whether or not a particular mutant has been requested by an independent investigator.

Interested parties may contact Jackson Labs at faces@jax.org.

The Jackson Laboratory

Recent Updates: The following mice have either been added or have recent changes.

Mutant Mice Being Characterized

	C57BL/6J-Nm3099 The phenotype of this dominant mutation is a mildly shortened nose. Initial hearing tests, conducted on three mutants and two controls, produced normal results. Both male and female mutants are fertile. This strain is now only available through cryo. recovery. More Details
	C57BL/6J-Nm3140 The phenotype of this dominant mutation consists of short front legs, small ear pinnae, and a square, fat body. Initial hearing tests, conducted on four mutants, produced normal results. The mutant in this picture is a ten week old female. This strain is now only available through cryo. recovery More Details
	C57BL/6J-nm3244 The phenotype of this heritable mutation consists of a shortened nose. Results of initial hearing exams on 2 mutants and 2 controls were normal. The mutant in this picture is a 15 week old male. More Details
	B6;A-nm3014 The phenotype of this heritable mutation is a shortened nose. The mutant in this picture is a 31 week old female. This strain was discarded due to the subtlety of its phenotype and is now only available through cryo. recovery. More Details
	*NOD.ALR-(D17Mit16-D17Mit10* )/Lt-nm3283** The phenotype of this heritable mutation is a shortened nose. The mutant in this picture is a 10 week old female. This strain has been discarded due to the subtlety of its phenotype and is now only available through cryo. recovery. More Details
	CXB5/ByJ-nm2886 The phenotype of this heritable mutation is quite variable. It can consist of any combination of low set, small and/or lopped ear pinnae and can effect the ear pinnae on both or either side of the skull. The phenotype can also vary in severity. Results from initial hearing tests were normal. The mutant in this picture is a 29 week old female. More Details
	*C57BL/6J-Slc30a4<lm>/J-nm3305* The phenotype of this heritable mutation is a shortened nose. Initial hearing tests found one mutant to be deaf in both ears. The mutant in this picture is a 12 week old female. More Details
	*B6.129P2-Apoa1<tm1Unc>/J-nm2834* Mutants with this heritable phenotype have short noses. Results from initial hearing tests were normal. The mutant in this picture is a 33 week old female. This strain is now only available through cryo. recovery. More Details
	B6CBA-Tg(HDexon1)62Gpb/1J-nm3250 The phenotype of this heritable mutation consists of a small overall body size and a short, rounded nose. Initial hearing tests were conducted on two mutants; results were normal. Eye morphology was examined on two mutants; no obvious abnormalities were observed. The mutant in this picture is a 5 week old male. This strain is now only available through cryo. recovery. More Details
	*C57BL/6J-Lyst<bg-J>/J-nm3366* The phenotype of this heritable mutant is a short nose. The mutant in this picture is a 7 week old male. More Details
	*B6.129P2-Pltp<tm1Jia>/J-nm3382* The phenotype of this heritable mutation is a short nose. Initial eye examinations revealed no obvious abnormalities. The mutant is this picture is a 19 week old female. More Details
	C58/J-Nm3390 The phenotype of this mutant is a short nose. The mutant in this picture is a 25 week old male. More Details
	C57BL/6-Tg(ACTbEGFP)1Osb/J-Nm3431 The phenotype of this dominant mutation consists of a short, blunt, upturned nose. The female mutant and male littermate control pictured are six months old. More Details
	*B6.SJL-Ptprc<a> Pep3<b>/BoyJ-nm3436* The phenotype of this mutant consists of a short nose, one missing eye and small overall body size. The mice in this picture are 9 week old females. More Details
	*NOD.129S2-Stat4<tm1Gru>/JbsJ-nm3536* The phenotype of this deviant consists of a short nose, and wide set eyes. The mice in this picture are seven week old males. More Details
	DBA/2J-nm3525 The phenotype of this dominant mutation consists of large eyes and a short nose. Initial eye examinations completed on the original mutant, only found abnormalities consistent with background strain and advanced age. The mutant in this picture is a fifty-three week old male. More Details
	B6CBA-Tg(HDexon1)62oGpb/J-nm3520 This deviant's phenotype consists of one low set ear pinna. The deviant in this photo is a nine week old female. More Details
	CBA/J-nm3526 The phenotype of this deviant consists of one lopped and low set ear pinna. The deviant in this picture is a five week old male. More Details
	CBA/J-nm3514 This deviant's phenotype consists of two malformed ear pinnae. The mice in this picture are five week old females. This strain has been discarded because the phenotype is not heritable. More Details
	DBA/1J-nm3511 This deviant's phenotype consists of two shortened ear pinnae. The mice in this picture are nine week old females. This strain has been discarded because the phenotype is not heritable. More Details
	B6AF1/J-nm3573 The phenotype of this deviant consists of an almost absent right ear pinna. The mice in this photograph are 12 week old males. More Details
	*B6C3Fe a/a-Csf1<op>/J-nm3589* The phenotype of this deviant consists of one low set ear pinna. The male deviant and female control in this photograph are 7 weeks old. More Details
	*B6;129-Cd44<tm1Hbg>/J-nm3540* The phenotype of this deviant consists of one lowest ear pinna and small overall body size. The deviant in this photo is an 18 week old male. More Details
	*B6.D2-Kitl/J-nm3472* The phenotype of this deviant consists of a short nose. The deviant in this picture is a 57 week old male. More Details
	CBA/J-nm3547 The phenotype of this deviant consists of an asymmetrical low set ear pinna. The deviant in this picture is a 21 week old male. More Details
	NOD/LtJ-nm3549 The phenotype of this deviant consists of a shortened nose. The deviant in this picture is a 29 week More Details
	C57BL/6J-nm3501 The phenotype of this recessive mutation consists of overall skull asymmetry. The mutant female and control male in this photo are 14 weeks old. More Details
	*B6.V-Lep<ob>/J-nm3530* The phenotype of this deviant consists of a domed skull and white cornea. Initial eye examination revealed abnormal blood vessels and lack of pigment in cornea. The mice in this picture are 5 week old females. More Details
	*BALB/cByJ-mshi/J-nm3639* The phenotype of this deviant consists of one low set, malformed ear pinna and overall skull asymmetry. The deviant in this picture is a 14 week old male. More Details
	STOCK-nm3580 The phenotype of this heritable mutation consists of a short nose. The mutant female and control male in this picture are 8 weeks old. More Details