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Publications

The following is a list of all published articles since 1988.  Citations are listed in chronological order. To search, use your browser's Find function by typing Control/F, then enter a key word or phrase.  Send any reprint requests to psacket@jhmi.edu.

Papers:

1.          Dawson, V.L., T.M. Dawson and J.K. Wamsley.  "Quantitative Autoradiographic Localization of Drug and Neurotransmitter Receptors in the Olfactory Bulb."  In: Molecular Neurobiology of the Olfactory Bulb: Molecular, Membranous, and Cytological Studies., eds. F.L. Margolis and T.V. Getchell, Plenum Press, New York, NY, pp. 99-117 (1988).

2.          Dawson, V.L., T.M. Dawson, F.M. Filloux and J.K. Wamsley.  "Evidence for Dopamine D-2 Receptors on Cholinergic Interneurons in the Rat Caudate-Putamen."  Life Sci. 42:1933-1939 (1988).

3.          Dawson, V.L., F.H. Gage, M.H. Hunt, and J.K. Wamsley.  "Normalization of Subtype-Specific Muscarinic Receptor Binding in the Denervated Hippocampus by Septodiagonal Band Grafts."  Expt. Neurol. 106:115-124 (1989).

4.          Dawson, V.L., and J.K. Wamsley.  "Hippocampal Muscarinic Supersensitivity After AF64A Medial Septal Lesion Excludes M1 Receptors."  Brain Res. Bull. 25:311-317 (1990).

5.          Dawson, V.L., T.M. Dawson, and J.K. Wamsley.  "Muscarinic and Dopaminergic Receptor Subtypes on Striatal Cholinergic Interneurons."  Brain Res. Bull. 25:903-912 (1990).

6.          Williams, K.W., V.L. Dawson, C. Romano, M.A. Dichter, and P.B. Molinoff.  "Characterization of Polyamine Sites Having Agonist, Antagonist, and Inverse Agonist Effects at the Polyamine Site of the NMDA Receptor."  Neuron  5:199-208 (1990).

7.          Dawson, T.M., V.L. Dawson, L.J. Fisher, F.H. Gage, and J.K. Wamsley.  "Functional Recovery of Supersensitive Dopamine Receptors After Intrastriatal Grafts of Fetal Nigra."  Expt. Neurol. 111:282-292 (1991).

8.          Dawson, T.M., V.L. Dawson, F.H. Gage, L.J. Fisher, M.A. Hunt and J.K. Wamsley.  "Down Regulation of Muscarinic Receptors in the Rat Caudate-Putamen After Lesioning of the Ipsilateral Nigrostriatal Dopamine Pathway with 6-Hydroxydopamine (6-OHDA): normalization by Fetal Mesencephalic Transplants."  Brain Res. 540:145-152 (1991).

9.          Wamsley, J.K., T.M. Dawson, V.L. Dawson, M.A. Hunt, L.J. Fisher, and F.H. Gage.  "Reversal of Nigrostriatal-Lesion Induced Receptor Alterations by Grafting of Fetal Mesencephalic Dopaminergic Neurons."  In Neuroreceptor Mechanism's in Brain, eds. S. Kito, T. Segawa and R. Olsen, Plenum Press, New York, NY, p221-235 (1991).

10.      London, E.D., V.L. Dawson, and C.R. Mantione.  "Specific Binding Sites for Polyamines in Mammalian Brain."  In NMDA Related Agents: Biochemistry, Pharmacology and Behavior, eds. T. Nabeshima, T. Kameyama, and E.F. Domino.  Proceedings from a satellite symposium of the 17th Congress of Collegium Internationale Neuro-Psychopharmacologicum, Nagoya, Japan, NPP Books, Inc., Ann Arbor, MI, Sept. p71-78 (1991).

11.      Dawson, V.L., T.M. Dawson, E.D. London, D.S. Bredt, and S.H. Snyder. "Nitric Oxide Mediates Glutamate Toxicity in Primary Cortical Cultures."  Proc. Natl. Acad. Sci. USA 88:6368-6371 (1991).

12.      Dawson, V.L., M.A. Hunt and J.K. Wamsley.  "Alterations in Cortical Muscarinic Receptors Following Cholinotoxin (AF64A) Lesion of the Rat Nucleus Basalis Magnocellularis."  Neurobiol. Aging 13:25-32 (1991).

13.      Dawson, T.M., V.L. Dawson and S.H. Snyder. "Neurological Progress: A Novel Neuronal Messenger Molecule in Brain: The Free Radical, Nitric Oxide (NO)." Ann. Neurol. 32:297-311 (1992).

14.      Dawson, T.M., V.L. Dawson and S.H. Snyder. "Nitric Oxide as a Mediator of Neurotoxicity." in Assessing Neurotoxicity of Drugs of Abuse, ed L. Erinoff, NIDA Research Monograph Series Volume 136:253-273 (1993).

15.      Dawson, V.L., T.M. Dawson, D.A. Bartley, G.R. Uhl, and S.H. Snyder. "Mechanisms of Nitric Oxide Neurotoxicity in Primary Brain Cultures." J. Neurosci. 13:2651-2661 (1993).

16.      Kusama, T., C.S. Spivak, P. Whiting, V.L. Dawson, J.C. Schaeffer and G.R. Uhl. "Pharmacology of GABA Rho1 and GABA Alpha/Beta Receptors Expressed in Xenopus oocytes and COS cells." Brit. J. Pharmacol. 109:200-206 (1993).

17.      Dawson, T.M., J.P. Steiner, V.L. Dawson, J.L. Dinerman, G.R. Uhl and S.H. Snyder. "Immunosupressant, FK-506, Enhances Phosphorylation of Nitric Oxide Synthase Against Glutamate Neurotoxicity." Proc. Natl. Acad. Sci., USA  90:9808-9812 (1993)

18.      Dawson, V.L., T.M. Dawson, G.R. Uhl and S.H. Snyder. "Human Immunodeficiency Virus-1 Coat Protein Neurotoxicity Mediated by Nitric Oxide in Primary Cortical Cultures." Proc. Natl. Acad. Sci., USA  90:3256-3259 (1993).

19.      Dawson, V.L., C.Y. Hsu, T.H. Liu, T.M. Dawson and J.K. Wamsley.  "Receptor Alterations in Subcortical Structures After Bilateral Middle Cerebral Artery Infarction of the Cerebral Cortex."  Expt. Neurol. 128:88-96 (1994).

20.      Dawson,T.M., K. Hung, V.L. Dawson, J.P. Steiner, S.H. Snyder. "Neuroprotective effects of  Gangliosides May Involve Inhibition of Nitric Oxide Synthase." Ann. Neurol., 37: 115-118 (1995).

21.      Pogun, S., V.L. Dawson, and M.J. Kuhar. "Nitric Oxide Inhibits [3H]Glutamate Transport in Synaptosomes." Synapse 18: 21-26 (1994).

22.      Zhang, J., V.L. Dawson, T.M. Dawson and S.H. Snyder. "Nitric Oxide Activation of Poly (ADP-ribose) Synthetase in Neurotoxicity." Science 263:687-689 (1994)

23.      Zhang J., V.L. Dawson , T.M. Dawson and S.H. Snyder.  "ADP-Ribosylation as a cGMP-Independent Pathway to Terminate Nitric Oxide Effects"  In Taniguchi Symposia on Brain Science No. 17: Nitric Oxide Roles in Neuronal Communication and Neurotoxicity.  ed. H. Takagi, N. Toda, R.D. Hawkins, CRC Press, Baco Raton FL pp223-234 (1994)

24.      Dawson, T.M., V.L. Dawson and S.H. Snyder.  "Molecular Mechanisms of Nitric Oxide Actions in the Brain."  In Neurobiology of NO• and •OH.  ed. C. Chieuh, Annals of the New York Academy of Science.  738: 76-85 (1994).

25.      Dawson V.L., H.P. Brahmbhatt, J.A. Mong and T.M. Dawson.  "Expression of Inducible Nitric Oxide Synthase Causes Delayed Neurotoxicity in Primary Mixed Neuronal-Glial Cortical Cultures."  Neuropharmacology  33: 1425-1430 (1994)

26.      Dawson, T.M., and V.L. Dawson  "Nitric Oxide Actions and Pathological Roles."  The Neuroscientist  1: 9-20 (1994)

27.      Dinerman J.L., J.P. Steiner, T.M. Dawson, V.L. Dawson , and S.H. Snyder. "Cyclic Nucleotide Dependent Phosporylation of Neuronal Nitric Oxide Synthase Inhibits Catalytic Activity." Neuropharmacol.  33: 1245-1252 (1994)

28.      Dawson, T.M., and V.L. Dawson . "gp120 Neurotoxicity in Primary Cortical Cultures."  Adv. Neuroimmunol.  4: 167-173 (1994)

29.      Dawson, T.M., and V.L. Dawson  "ADP-Ribosylation as a Mechanism for Nitric Oxide's Action in the Nervous System."  New Horizons  3: 86-92 (1995)

30.      Dawson V.L. and T.M. Dawson "Physiologic and Toxicologic Actions of Nitric Oxide in the Central Nervous System." Adv. Pharmacol. 34: 323-342 (1995).

31.      Dawson V.L. and T.M. Dawson "Nitric Oxide Neurotoxicity In Primary Neuronal Cultures."  In The Proceedings of the Nineteenth Princeton Conference.  ed. M.A. Moskowitz, Butterworth-Heinemann, Boston, MA  pp. 3-17 (1995).

32.      Dawson, V.L.and T.M. Dawson "Nitric Oxide Mediates a Componant of gp120 Neurotoxicity in Primary Cortical Cultures."  in Technical Advances in AIDS Research in the Human Nervous System. ed. E. Major, Plenum Publishing Corp. pp163-173 (1995).

33.      33.  Dawson, T.M., J. Zhang, V.L. Dawson and S.H. Snyder.  "Nitric Oxide:  Cellular Regulation and Neuronal Injury"   In Proceedings of the 5th International Symposium on Neurodegeneration.   ed F.J. Siel, Progress in Brain Research, 103: 365-369 (1994).

34.      Dawson V.L. and T.M. Dawson "Mechanisims of Nitric Oxide Neurotoxicity In Primary Neuronal Cultures." In World Congress on Alternatives and Animal Use in the Life Sciences: Education, Research and Testing.  ed. A.M. Goldberg, Mary Ann Liebert, Inc Publishers, New York, NY Vol 11 pp 133-139  (1995).

35.      Dawson V.L. and T.M. Dawson "Nitric Oxide Toxicity in Central Nervous System Cultures."  in Paradigms of Neural Injury  ed. J.R. Perez-Polo, Academic Press Inc., San Diego CA, pp. 26-43 (1996)

36.      Dawson V.L.  "Nitric Oxide: Role in Neurotoxicity."  Clin. Expt. Pharmacol. Physiol.  22: 305-308 (1995)

37.      Dawson, T.M., and V.L. Dawson.  “NG-nitro-L-arginine delays the development of brain injury during focal ischemia in the rat.”  Editorial Comment in Stroke, 26: 288-289 (1996).

38.      Linden D.J., Dawson, T.M., and V.L. Dawson  "An Evaluation of the Nitric Oxide/cGMP/cGMP-Dependent Protein Kinase Cascade in the Induction of Cerebellar Long-Term Depression." J. Neurosci.  15: 5098-5105 (1995).

39.      Dawson, V.L. and T.M. Dawson.  “Nitric Oxide Actions in Neurochemistry.”  Neurochemistry International in press (1996).

40.      Dawson, V.L.  “Induction of DNA Fragmentation After 10-120 minutes of Focal Cerebral Ischemia in Rat”  Editorial Comment in Stroke, 26:1257-8 (1995).

41.      Nelson, R.J., G.E. Demas, P.L. Huang M.C. Fishman, V.L. Dawson, T.M. Dawson and S.H. Snyder.  “Behavioral Abnormalities in Male Mice Lacking Neuronal Nitric Oxide Synthase.”  Nature 378: 383-386 (1995).

42.      Dawson, T.M. and V.L. Dawson.  “Nitric Oxide Synthase:  Role as a Transmitter/Mediator in the Brain and Endocrine System.”  Ann. Rev. Medicine.ed. CH Coggins, EW Hancock and LJ Levitt, Annual Reviews Inc., Palo Alto, CA  47: 219-227 (1996).

43.      43.  Dawson, T.M., and V.L. Dawson   "Nitric Oxide and Neurotransmission."  In Tissue Oxygen Deprivation: Developmental Molecular and Integrated Function.  ed. GG. Haddad and G. Lister, Marcel Dekker Inc., New York, NY,  669-699 (1996).

44.      Dawson, V.L. and T.M. Dawson  “Nitric Oxide in Neuronal Degeneration.”  Proc. Soc. Expt. Biol. Med. 211(1): 33-40 (1996).

45.      Dawson, V.L. and T.M. Dawson.  “Free radicals and neuronal cell death.”  Cell Death and Differentiation 3:71-78 (1996).

46.      Bao, J., A.H. Sharp, M.V. Wagster, M. Becher, G. Schilling, C.A. Ross, V.L. Dawson, and T.M. Dawson.  “Expansion of Polyglutamine Repeat in Huntingtin Leads to Abnormal Protein Interactions Involving Calmodulin.”  Proc. Natl. Acad. Sci. USA  93: 5037-5042 (1996).

47.      Przedborski S., V. Jackson-Lewis, R. Yokoyama, T. Shibata, V.L. Dawson, and T.M. Dawson.  “Role of Neuronal Nitric Oxide Synthase in 1-methyl-4-phenyl-1,2,3,6-tetrahydrophyridine (MPTP)-Induced Dopaminergic Neurotoxicity.”  Proc. Natl. Acad. Sci. USA 93: 4565-4571 (1996).

48.      Dawson, T.M. and V.L. Dawson.  “Generation of Isoform Specific Antibodies to the Nitric Oxide Synthases.”  in Nitric Oxide A Volume of Methods in Enzymology.  ed. L. Packer, Academic Press, Orlando, FL,  268: 349-358 (1996).

49.      Dawson, T.M. and V.L. Dawson.  “Protection of The Brain From Ischemia.”  in Cerebrovascular Disease, eds. H. H. Batjer, L. R. Caplan, L. Friberg, R. Greenlee Jr., T. A. Dpoitnik, and W.L. Young, Lippincott-Raven Publishers, New York, NY 29: 1-7 (1996).

50.      Dawson, V.L., and T.M. Dawson.  “Therapeutic approaches with nitric oxide synthase inhibitors.”  in Neurodegenerative Diseases: Mitochondria and Free Radicals in Pathogensis.  ed. M.F. Beal, I. Bodis-Wollne and N. Howell,  Academic Press in press (1996).

51.      Dawson, V.L., and T.M. Dawson.  “Nitric oxide neurotoxicity.”  J. Chem. Neuroanat.  10:179-190 (1996).

52.      Adamson, D.C., C. Zink, J. Clements, T.M. Dawson, and V.L. Dawson.  “Apoptosis in the CNS of SIV infected rhesus macaques with neurologic disease but not in SIV infected rhesus macaques without neurologic disease.”  Molec. Med.  2:417-428 (1996).

53.      Dawson, V.L. and T.M. Dawson. "Nitric oxide actions in the nervous system"  In Neurodegenerative Diseases: Molecular and Cellular Mechanisms and Therapeutic Advances.  ed. G. Fiskum,  Plenum Press, NY pp. 247-262 (1996).

54.      Dawson, V.L. and T.M. Dawson.  “Pathologic Roles of Nitric Oxide in the Central Nervous System.,  in Free Radicals in Brain Physiology and Disorders.”  eds.  L. Packer, M. Hiramatsu and T. Yoshikawa, Academic Press Inc., Orlando, FL, pp 83-99 (1996)

55.      55.  Dawson, V.L., V.M. Kizushi, P.L. Huang, S.H. Snyder and T.M. Dawson.  “Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase defcient mice.”  J. Neurosci   16:2479-2487 (1996).

56.      Dawson, V.L., Dawson, T.M., "NItric oxide actions in neurochemistry" in Neurochemistry International, 1996 August, 29(2): 97-110

57.      Dawson, V.L, and T.M. Dawson.  “Nitric oxide toxicity in CNS cultures.”  in Methods in Neuroscience  30:26-43 (1996).

58.      Xia Y., V.L. Dawson, T.M. Dawson, S.H. Snyder and J.L. Zweier.  “Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite mediated cellular injury.” Proc. Natl. Acad. Sci. USA  93: 6770-6774 (1996).

59.      Dawson, V.L. and T.M. Dawson.  “Function of Nitric Oxide in Neuronal Cell Death.” in: Methods in Neuroscience: Nitric Oxide Synthase - Methods for Characterization and Functional Analysis.  ed. M. Maines, Academic Press, San Diego, CA, 31:228-240 (1996).

60.      Dawson, T.M. and V.L. Dawson.  “NADPH Diaphorase Staining.” in: Methods in Neuroscience: NO Synthase - Methods for Characterization and Functional Analysis of Nitric Oxide Synthase.  ed. M. Maines, Academic Press, San Diego, CA, 31: 62-67 (1996).

61.      Resink, A.M., V.L. Dawson, and T.M. Dawson.  “Nitric Oxide Inhibitors:  Future Therapies for CNS Disorders.”  CNS Drugs Review, 6: 351-357 (1996)

62.      Yun, H.Y., Dawson, V.L., and T.M. Dawson.  “Neurobiology of Nitric Oxide.” Critical Reviews in Neurobiology,  10: 291-316 (1996).

63.      Burnett, A.L., R.J. Nelson, D.C. Calvin, J-X Liu, G.E. Demas, S.L. Klien, L.J. Kriegsfeld, V.L. Dawson, T.M. Dawson and S.H. Snyder.  “Nitric oxide dependent penile erection in mice lacking neuronal nitric oxide synthase.”  Molec. Med.  2: 288-286 (1996).

64.      Adamson, D.C., B. Wildemann, M. Sasaki, J. McArthur, J. Glass, V.I. Christov T.M. Dawson and V.L. Dawson.  “Immunologic NO Synthase: Elevation in Severe AIDS Dementia and Induction by HIV-1 gp41.”  Science  274: 1917-1921 (1996).

65.      Burnett A.L., D.C. Calvin, S.L. Chamness, J.-X. Liu, V.L. Dawson, T.M. Dawson, S.H. Snyder.  “Urinary Bladder-Urethral Sphincter Dysfunction in Mice with Targeted Disruption of Neuronal Nitric Oxide Synthase Models Idiopathic Voiding Disorders in Humans.”  Nature Med., 3: 571-574 (1997).

66.      Yun, H.-Y, V.L. Dawson and T.M. Dawson.  “Nitric Oxide in  Health and Disease.”  Molec. Psychiatry  2: 300-310 (1997).

67.      Togashi, H., M. Sasaki, E. Frohman, E. Taira, R.R. Ratan, T.M. Dawson and V.L. Dawson.  “Neuronal (Type I) Nitric Oxide Synthase Regulates NF B Activity and Immunologic (Type II) Nitric Oxide Synthase Expression.”  Proc. Natl. Acad. Sci. USA  94: 2676-2680 (1997).

68.      Samdani, A.F., C. Newcamp, A. Resink, F. Facchinetti, B.E. Hoffman, V.L. Dawson and T.M. Dawson.  “Differential Susceptibility to Neurotoxicity is Mediated by Neurotrophins and Neuronal Nitric Oxide Synthase.”  J. Neurosci. 17: 4633-4641 (1997).

69.      Samdani, A.F, T.M. Dawson and V.L. Dawson.  “Nitric Oxide Synthase in Models of Focal Ischemia.” Stroke, 28: 1283-1288 (1997).

70.      Kriegsfeld L.J., T.M. Dawson,  V.L. Dawson, R.J. Nelson, and S.H. Snyder.  “Aggressive Behavior in Male Mice Lacking the Gene for Neural Nitric Oxide Synthase is Testosterone-Dependent.”  Brain Res.  769: 66-70 (1997)

71.      Nelson, R.J., L.J. Kriegsfeld, V.L. Dawson, and T.M. Dawson.  “Effects of Nitric Oxide on Neuroendrocrine Function and Behavior.”  Frontiers in Neuroscience, 18:463-491 (1997).

72.      Eliasson, M.J.L., K. Sampei, A.S. Mandir, P.D. Hurn, R.J. Traystman, J. Bao, A. Pieper, Z.-Q. Wang, T.M. Dawson, S.H. Snyder, and V.L. Dawson.  “Poly(ADP-Ribose) Polymerase Gene Disruption Renders Mice Resistant to Cerebral Ischemia.”  Nature Med.  3:1089-1095 (1997).

73.      Demas, G.E,. M.J.L. Eliasson, T.M. Dawson, V.L. Dawson, L.J. Kriegsfeld, R.J. Nelson, and S.H. Snyder.  “Inhibition of Neuronal Nitric Oxide Synthase Increases Aggressive Behavior in Mice.”  Molec. Med.  3: 611-617 (1997).

74.      Dawson, V.L. and T.M. Dawson.  “Nitric Oxide Neurotoxicity in Models of Ischemic Damage.”” in Frontiers in Cerebrovascular Disease:  Mechanisms, Diagnosis, and Treatment.  eds.  J.T. Robertson and T.S. Jr. Nowak.  Futura Publishing Company, Inc. Armonk, NY  pp:149-163 (1998)

75.      Facchinetti F., V.L. Dawson and T.M. Dawson.  “Free radicals as mediators of neuronal injury.”  Cell. Mol.. Neurobiol.  18: 6 667-682 (1998).

76.      Gonzalez-Zulueta, M., G. Mukhin, L. Ensz, R.M. Zwacka, J.F. Engelhardt, L.W. Oberley, V.L. Dawson, and T.M. Dawson.  “Manganese Superoxide Dismutase Protects nNOS Neurons From NMDA and Nitric Oxide Mediated Neurotoxicity.”  J. Neurosci.  18: 2040-2055 (1998).

77.      Weiss, S.W., D.S. Albers, M. J. Iadarola, T.M. Dawson, V.L. Dawson, D.G. Standaert.  "NMDAR1 Glutamate Receptor Subunit Isoforms in Neostriatal, Neocortical and Hippocampal Nitric Oxide Snythase Neurons." J. Neurosci. 18: 1725-1734 (1998).

78.      Crosbie, R.H., V. Straub, H.Y. Yun, J.C. Lee, J.A. Rafael, J.S. Chamberlain, V.L. Dawson, T.M. Dawson and Kevin P. Campbell. "mdx Muscle Pathogenesis is Independent of nNOS Perturbations."  Human Molecular Genetics, 7: 823-9 (1998).

79.      Dawson, V.L., J. Kusel and T.M. Dawson.  “Nitric Oxide: Diverse Actions in the CNS and PNS.” The Neuroscientist  4(2): 96-112 (1998).

80.      Cooper, J.K., G. Schilling,, M.F. Peters, W.J. Herring, A.H. Sharp, Z. Kaminsky, J. Masone, F.A. Khan, M. Delanoy, D.R.  Borchelt, V.L. Dawson, T.M. Dawson, and C.A. Ross.  "Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture," Hum Mol Genet, 7: 783-90 (1998).

81.      Yun, H-Y., M. Gonzalez-Zulueta, V.L. Dawson, and T.M. Dawson.  “Nitric Oxide Mediates NMDA Receptor Induced Activation of p21ras.”  Proc. Natl. Acad. Sci, USA 95: 5773-5778 (1998).

82.      Szabo, C., and V.L. Dawson.  "Role of poly(ADP-ribose) synthetase in inflammation and ischaemia- reperfusion." Trends Pharmacol Sci, 19: 287-98 (1998).

83.      Dawson, T.M. and V.L. Dawson.  “Nitric Oxide in the Nervous System.”  in Encyclopedia of Neuroscience.  eds. G. Adelman and B. Smith, Elsevier Science, Amsterdam, The Netherlands, pp 1473-1476 (1999).

84.      Facchinetti, F., M. Sasaki, D. Reif, M.F. Beal, T.M. Dawson, M.E. Gurney and V.L. Dawson.  “Possible Involvement of Neuronal Nitric Oxide Synthase in the Pathogenesis of a Transgenic Mouse Model of Familial Amyotrophic Lateral Sclerosis.”  Neurosci.  90: 1483-1492 (1999).

85.      Gonzalez-Zulueta, M., H.-Y. Yun, V.L. Dawson and T.M. Dawson.  "Nitric Oxide Mediates Activity-Dependent Neuronal Survival."  in The Biology of Nitric Oxide, Part 6,  Eds. S. Moncada, A. Higgs, Portland Press Ltd. London, in press (1998).

86.      Yun, H.-Y., Gonzalez-Zulueta, M. V.L. Dawson and T.M. Dawson.  "Nitric Oxide Mediates NMDA Receptor-Stimulate Calcium Activation of Ras/Erk."  in The Biology of Nitric Oxide, Part 6,  Eds. S. Moncada, A. Higgs, Portland Press Ltd. London, in press (1998).

87.      Togashi, H., M. Sasaki, T.M. Dawson, V.L. Dawson.  "Neuronal (Type I) Nitric Oxide Synthase Regulates NFkB Activity and Immunologic (Type II) Nitric Oxide Synthase Expression." in The Biology of Nitric Oxide, Part 6,  Eds. S. Moncada, A. Higgs, Portland Press Ltd. London, in press (1998).

88.      Dillman, J.F., V.L. Dawson and T.M. Dawson.  "Overview of the Pathway and Functions of Nitric Oxide" in Chapter 11: "The Nitric Oxide/Guanylate Cyclase Pathway" Current Protocols in Toxicology Eds. M. Maines and D. Reed., John Wiley & Sons, Inc., NY, NY, in press (1998).

89.      Gonzalez-Zulueta, M., V.L. Dawson and T.M. Dawson.  "Histochemical Analysis of Nitric Oxide Synthase - NADPH Diaphorase Staining" in Chapter 11: "The Nitric Oxide/Guanylate Cyclase Pathway" Current Protocols in Toxicology Eds. M. Maines and D. Reed., John Wiley & Sons, Inc., NY, NY, in press (1998).

90.      Dawson, T.M., M. Sasaki, M. Gonzalez-Zulueta, M., V.L. Dawson, “Regulation of Neuronal Nitric Oxide Synthase and Identification of Novel Nitric Oxide Signaling Pathways.”  In Progress in Brain Research 118: Nitric Oxide in Brain Development, Plasticity and Disease, eds. RR Mize, TM Dawson, VL Dawson, MJ Friedlander,  Progress in Brain Research Elsevier Press, Amsterdam, Denmark, 118: 3-12 (1998).

91.      Dawson, V.L. and T.M. Dawson.  “Nitric Oxide in Neurodegeneration.” .”  In Progress in Brain Research 118: Nitric Oxide in Brain Development, Plasticity and Disease, eds. RR Mize, TM Dawson, VL Dawson, MJ Friedlander, Progress in Brain Research, Elsevier Press, Amsterdam, Denmark, 118: 215-230 (1998).

92.      Dawson, V.L.  "Tacrolimus (FK506) Attenuates Leukocyte Accumulation After Transient Retinal Ischemia- Comment"  Stroke  29: 1437-1438.

93.      Dawson, V.L.  "Matrix Metalloproteinase Expression Increases after Cerebral Focal Ischemia in Rats-Inhibition of Matrix Metalloproteinase 9 Reduces Infarct Size - Comment"  Stroke  29: 1030.

94.      Klein, S.L., D. Carnovale, A.L. Burnett, E.E. Wallach, H.A. Zacur, J.K. Crone, V.L. Dawson, R.J. Nelson, and T.M. Dawson.  “Impaired Ovulation in Mice with Targeted Deletion of the Neuronal Isoform of Nitric Oxide Synthase.”  Mol. Med. 4: 658-664 (1998).

95.      Jumrussirikul, J. Dinerman, T.M. Dawson, V.L. Dawson, U. Ekelund, D. Georgakopoulos, L.P. Schramm, H. Calkins, S.H. Snyder, J. Hare, R.D. Berger.  "Interaction Between Neuronal Nitric Oxide Synthase and Inhibitory G Protein Activity in Heart Rate Regulation in Conscious Mice.  J. Clin. Invest., 102: 1279-1285 (1998)

96.      Facchinetti, F., M. Eves, M.E. Gurney, T.M. Dawson and V.L. Dawson.  "Increase Susceptibility of Slowly Triggered Excitotoxicity and Oxidative Damage in Primary Neuronal Cultures From a Transgenic Mouse Model of Familial Amyotrophic Lateral Sclerosis.  Brain Res., submitted (1998).

97.      Dawson, V.L. and T.M. Dawson.  “Regulation of Nitric Oxide Synthesis and Neurotoxicity,” in Chapter 15 of Molecular Biology of the Toxic Response.  ed. A. Puga and K. Wallace, TechBook Press, pp 255-265 (1998).

98.      Facchinetti, F, V.L. Dawson and T.M. Dawson.  "Free Radicals as Mediators of Neuronal Injury."  Cellular and Molecular Neurobiology, 18: 667-682 (1999).

99.      Sasaki, M., T.M. Dawson, and V.L. Dawson.  “Blocking Nitric Oxide Toxicity.” in Chapter 7 of Handbook of Experimental Pharmacology: CNS Neuroprotection.  ed. F.W. Marcoux and D.W. Choi,  Springer-Verlag, in press (1999).

100.   Sasaki, M., T.M. Dawson, and V.L. Dawson.  “NO and Brain Ischemia/Reperfusion Injury.” in Chapter 25 of Handbook of Experimental Pharmacology: Nitric Oxide.  ed. B. Mayer,  Springer-Verlag, in press (1999).

101.   Adamson, D.C., J.C. McArthur, T.M. Dawson, and V.L. Dawson. “Course of HIV-Associated Dementia: Correlation’s with gp41, iNOS and Macrophage/Microglial Activation.”  Mol. Med.  5: 98-109 (1999).

102.   Adamson, D.C., K.L. Kopnisky, T.M. Dawson, and V.L. Dawson. “Mechanisms and Structural Determinants of HIV-1 Coat Protein gp41-Induced Neurotoxicity.”  J. Neurosci. 19: 64-71 (1999).

103.   Wei, G. V.L. Dawson and J.L. Zweier.  “Role of Neuronal And Endothelial Nitric Oxide Synthase in Nitric Oxide Generation in the Brain Following Cerebral Ischemia.” Biochim. Biophys. ACTA 1455(1):23-24 (1999).

104.   Adamson, D.C., K.L. Kopnisky, T.M. Dawson, and V.L. Dawson. “Characterization of Nitric Oxide Pathways Mediating HIV-1 Coat Protein gp120-Induced Neurotoxicity.”  J. Neurochem.  submitted (1999).

105.   Gonzalez-Zulueta, M., V.L. Dawson, and T.M. Dawson.  “Nitric oxide is Required for BDNF-Mediated Activity-Dependent Neuronal Survival.”  Nature Med.  submitted (1999).

106.   Dawson, V.L. and T.M. Dawson.  “Poly(ADP-Ribose) Polymerase in Ischemia-Reperfusion Injury.” in The Proceedings of the 21st Princeton Conference.  ed. D.W. Choi, American Heart Association, Greenville, TX.  in press (1998).

107.   Dawson, V.L. and T.M. Dawson.  “Poly (ADP-Ribose) Inhibition as a Therapeutic Approach to Focal Ischemic Insult.” in Pharmacology of Cerebral Ischemia 1998  ed. J. Krieglstein. MedPharm Scientific Publishers, Stuttgart, Germany pp 289-298 (1998).

108.   Mandir, A.S., S. Przedborski, V. Jackson-Lewis, Z.-Q. Wang, C. Simbulan-Rosenthal, M.E. Smulson, B.E. Hoffman, D.B. Guastella, S.H. Snyder, V.L. Dawson and T.M. Dawson,  “Poly (ADP-ribose) Polymerase Activation Mediates MPTP-induced Parkinsonism.” Proc. Natl. Acad. Sci. USA  96: 5774-5779 (1999).

109.   Sasaki, M., H. Huang, S. Ahn, D.D. Ginty, V.L. Dawson, and T.M. Dawson.  “Regulation of Neuronal Nitric Oxide Synthase Transcription Through Multiple Promoters and by a CREB Family Transcritpion Factor-Dependent Mechanism.”  J. Neurosci.  submitted (1999).

110.   Kriegsfeld L.J., G.E. Demas, S.E. Lee,  T.M. Dawson,  V.L. Dawson, and R.J. Nelson.  “Circadian Locomotor Analysis of Male Mice Lacking the Gene for Nitric Oxide Synthase (nNOS-/-).” J. Biol. Rhythms 14(1):19-26 (1999).

111.   Toung, T.J., A. Bhardwaj, V.L. Dawson, T.M. Dawson, R.J. Traystman, and P.D. Hurn.  “Neuroprotective FK506 Does Not Alter In Vivo Nitric Oxide Production During Ischemia and Early Reperfusion in Rats.”  Stroke 30:1279-1285 (1999).

112.   Dawson, V.L.  "Vulnerability and Resistance to Glutamate Excitotoxicity."  ISN News, International Society for Neurochemistry, 2: 32-36 (1999).

113.   Peters, M.F., F.C Nucifora, Jr., J. Kushi, H.C. Seaman, J.K Cooper, W.J. Herring, V.L. Dawson, T.M. Dawson, C.A. Ross.  "Nuclear targeting of mutant huntingtin increases toxicity". Mol. Cell Neurosci., (in press 1999).

114.   Liberatore, G.T., V. Jackson-Lewis, A.S. Mandir, J.W. McAuliffe, M. Vila, V.L. Dawson, T. M. Dawson, S. Przedborski.  “Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson’s disease.”  Nature Med.  submitted (1999).

115.   Dawson, V.L., Gonzalez-Zulueta, M., Dawson, T.M.. "Nitric oxide mediates ischemic pre-contidioning through p21Ras activation". The Biology of Nitric Oxide Part 7, eds. S. Moncada, L. Gustafsson, P. Wiklund, and E.A. Higgs.  In press (1999).

116.   Dawson, V.L., "Role of Nitric Oxide in HIV Dementia". NeuroAIDS. In press (1999).

117.   Toung, T.J., Bhardwaj, A., Dawson, V.L., Dawson, T.M, Traystman, R.J., Hurn, P.D., "Neuroprotective PF506 does not alter in vivo nitric oxide production during ischemia and early reperfusion in rats." Stroke.  (1999).

118.   Gonzalez-Zulueta, M., H.-Y. Yun, V.L. Dawson and T.M. Dawson.  "Nitric Oxide Mediates Activity-Dependent Neuronal Survival."  in The Biology of Nitric Oxide, Part 6,  Eds. S. Moncada, N. Toda, H. Maeda, E.A. Higgs,Portland Press Ltd. London, pp. 16 (1998).   

119.   Yun, H.-Y., Gonzalez-Zulueta, M. V.L. Dawson and T.M. Dawson.  "Nitric Oxide Mediates NMDA Receptor-Stimulate Calcium Activation of Ras/Erk." in The Biology of Nitric Oxide, Part 6,  Eds. Eds. S. Moncada, N. Toda,H. Maeda, E.A. Higgs, Portland Press Ltd. London, pp. 99 (1998). 

120.   Togashi, H., M. Sasaki, T.M. Dawson, V.L. Dawson.  "Neuronal (Type I) Nitric Oxide Synthase Regulates NFkB Activity and Immunologic (Type II) Nitric Oxide Synthase Expression." in The Biology of Nitric Oxide, Part 6,  Eds. Eds. S. Moncada, N. Toda, H. Maeda, E.A. Higgs, Portland Press Ltd. London, pp. 12 (1998).   

121.   Peters, M.F., Nucifora, F.C. Jr., Kushi, J., Seaman, H.C., Cooper, J.K., Herring, W.J., Dawson, V.L., Dawson, T.M., Ross, C.A.. "Nuclear Targeting of Mutant Huntingtin Increases Toxicity" in Molecular Cell Neuroscience, 1999 August, 14(2): 121-128. 

122.   Dawson, V.L.. "Potent neuroprotectants linked to bifunctional inhibition" in Protocols of the National Academy of Science USA.  1999 September 14: 96(19): 10557-10558. 

123.   Dawson, V.L., "Role of NO in HIV Dementia" in NeuroAids Vol. 2, Issue 9, October 29, 1999, http://mednav.com/zone/Naids/zones/Articles.

124. Gonzalez-Zulueta, M., A.B. Feldman, L.J. Klesse, R.G. Kalb, J.F. Dillman, L.F. Parada, T.M. Dawson, and V.L. Dawson.  "Requirement for Nitric Oxide Activation of Ras/Erk in Neuronal Ischemic Preconditioning" Proc. Natl. Acad. Sci. USA  in press (1999).

125. Dawson, V.L. and T.M. Dawson  "Neuronal Ischemic Preconditioning." Trends Pharmacol. Sci in press (2000). Dawson, T.M. "Parkinson's Disease: Clinical Manifestations and Treatment." International Journal of Psychiatry, 12:263-269  (2000).

126. Mandir, A.S., M.F. Poitras, A.R. Berliner, W.J. Herring, D.B. Guastella, A. Feldman, G.G. Poirer, Z.-Q. Wang, T.M. Dawson and V.L. Dawson.  “NMDA, But Not Non-NMDA Excitotoxicity is Mediated by Poly (ADP-Ribose) Polymerase.” J. Neuroscience, 20:8005-8011 (2000).

127. Sampei K., Mandir A.S., Asano Y., Wong P.C., Traystman R.J., Dawson V.L., Dawson T.M., Hurn P.D.  "Stroke outcome in double-mutant antioxidant transgenic mice." Stroke  31:2685-91 (2000).

128. Zhang, Y., J. Gao, K.K.K. Chung, H. Huang, V.L. Dawson and T.M. Dawson.  "Parkin Functions as an E2-Dependent Ubiquitin-Protein Ligase and Promotes the Degradation of the Synaptic Vesicle Associated Protein, CDCrel-1." Proc. Natl. Acad. Sci., U.S.A., 97:13354-13359 (2000).

129. Mandir, A.S., V.L. Dawson and T.M. Dawson.  "Gene Therapy to the Rescue in Parkinson's Disease."  Trends in Pharmacologic Sciences, 22:103-105 (2001).

130. Aghdasi, B., K.Ye, A. Resnick, A. Huang, H.C. Ha, X. Guo, T.M. Dawson, V.L. Dawson, and S.H. Snyder.  “FKBP12, the 12-kDa FK506-binding protein, is a physiologic regulator of the cell cycle.”  Proc. Natl. Acad. Sci., U.S.A. 98: 2425-2430 (2001).

131. Tanaka, Y., S. Engelender, S. Igarashi, R.K. Rao, T. Wanner, R.E. Tanzi, A. Sawa, V.L. Dawson, T.M. Dawson and C.A. Ross. "Inducible Expression a-Synuclein Sensitizes Cells to Mitochondria-Dependent Apoptosis."  Human Mol. Genetics, 10: 919-926 (2001).

132. Nandagopal, K., T.M. Dawson and V.L. Dawson.  "Critical Role for Nitric Oxide Signaling in Cardiac and Neuronal Ischemic Tolerance."  Journal of Pharmacology and Experimental Therapeutics, 297: 474-478 (2001).