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Selected Publications

Selected discoveries published by students in the Graduate Program in Biological Chemistry, students names in bold:

 20112010 | 2009 | | 20082007 | 2006 |  2005 | 2004 | 2003 | 2002 | 2001 |  2000 | 1999 | 1998 | 1997

 

2011

Gan, X., and Gould, S.J. Identification of an inhibitory budding signal that blocks the release of HIV particles and exosome/microvesicle proteins. Mol Biol Cell 22, 817-830.

He, L., Wang, X., Montell, D.J. Shining light on Drosophila oogenesis: live imaging of egg development. Curr Opin Genet Dev. 2011 Oct;21(5):612-9. Epub 2011 Sep 17.

Kim, J.H., Cho, A., Yin, H., Schafer ,D.A., Mouneimne, G., Simpson, K.J., Nguyen, K.V., Brugge, J.S., Montell, D.J. Psidin, a conserved protein that regulates protrusion dynamics and cell migration. Genes Dev. 2011 Apr 1;25(7):730-41. Epub 2011 Mar 15.

Kim, M.S., Zhong, J., Kandasamy, K., Delanghe, B., and Pandey, A. Systematic evaluation of alternating CID and ETD fragmentation for phosphorylated peptides. Proteomics 11, 2568-2572.

Shen, W., Adegbola, A.A., Luo, J., Chess, A. and Montell, C. (2011) Function of rhodopsin in temperature discrimination in Drosophila. Science, 1333-1336.

Song, W.J., Seshadri, M., Ashraf, U., Mdluli, T., Mondal, P., Keil, M., Azevedo, M., Kirschner, L.S., Stratakis, C.A., and Hussain, M.A. Snapin mediates incretin action and augments glucose-dependent insulin secretion. Cell Metab 13, 308-319.

Yoon, W.H., Meinhardt, H., Montell. D.J. miRNA-mediated feedback inhibition of JAK/STAT morphogen signalling establishes a cell fate threshold. Nat Cell Biol. 2011 Aug 21;13(9):1062-9. doi: 10.1038/ncb2316. PubMed PMID: 21857668; PubMed

Zeidan, Q., and Hart, G.W. The intersections between O-GlcNAcylation and phosphorylation: implications for multiple signaling pathways. J Cell Sci 123, 13-22.

2010

He L., Wang X, Tang HL, Montell DJ. (2010) Tissue elongation requires oscillating contractions of a basal actomyosin network. Nat Cell Biol, 12, 1133-42

Hesketh, G.G., Shah, M.H., Halperin, V.L., Cooke, C.A., Akar, F.G., Yen, T.E., Kass, D.A., Machamer, C.E., Van Eyk, J.E., and Tomaselli, G.F. (2010). Ultrastructure and regulation of lateralized connexin43 in the failing heart. Circ Res 106, 1153-1163.

Kane, L.A., Youngman, M.J., Jensen, R.E., and Van Eyk, J.E. (2010). Phosphorylation of the F(1)F(o) ATP synthase beta subunit: functional and structural consequences assessed in a model system. Circ Res 106, 504-513.

Kim, M.S., Kandasamy, K., Chaerkady, R., and Pandey, A. (2010). Assessment of Resolution Parameters for CID-Based Shotgun Proteomic Experiments on the LTQ-Orbitrap Mass Spectrometer. J Am Soc Mass Spectrom. 21, 1606-1611.

Kwon, Y., Kim, S.H., Ronderos, D., Lee, Y., Akitake, B. Woodward, O., Guggino, W.B., Smith, D. and Montell, C. 2010. Drosophila TRPA1 channel is required to avoid the naturally occurring insect repellent citronellal. Curr. Biol. 20, 1672-1678.

Kwon, Y., Shim, H.S., Shen, W. and Montell C. 2010. Fine thermotactic discrimination between the optimal and slightly cool temperatures via a TRPV channel in chordotonal neurons. J. Neurosci. 30, 10465-10471.

Wang, X., Wang, T., Jiao, Y., von Lintig, J., and Montell, C. (2010). Requirement for an enzymatic visual cycle in Drosophila. Curr Biol 20, 93-102.

Wang X.* , He L.* , Wu Y.I., Hahn K.M. & Montell D.J. Light-mediated activation reveals a key role for Rac in collective guidance of cell movement in vivo. Nature Cell Biology, 12, 591–597 (2010). * Co- first authors.

Wang, Z., Udeshi, N.D., Slawson, C., Compton, P.D., Sakabe, K., Cheung, W.D., Shabanowitz, J., Hunt, D.F., and Hart, G.W. (2010). Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesis. Sci Signal 3, ra2.

Zeidan, Q., and Hart, G.W. (2010). The intersections between O-GlcNAcylation and phosphorylation: implications for multiple signaling pathways. J Cell Sci 123, 13-22.

Zeidan, Q., Wang, Z., De Maio, A., and Hart, G.W. (2010). O-GlcNAc cycling enzymes associate with the translational machinery and modify core ribosomal proteins. Mol Biol Cell 21, 1922-1936.

 

2009

Jang, A. C.-C., Chang, Y.-C., Bai, J. and Montell, D.J.(2009) Border-cell migration requires integration of spatial and temporal signals by the BTB protein Abrupt. Nature Cell Biology. May; 11(5):569-79.

Lee, C.H., and Coulombe, P.A. (2009). Self-organization of keratin intermediate filaments into cross-linked networks. J Cell Biol 186, 409-421.

Moon, S.J., Lee, Y., Jiao, Y., and Montell, C. (2009). A Drosophila gustatory receptor essential for aversive taste and inhibiting male-to-male courtship. Curr Biol 19, 1623-1627.

 

 

2008

Jiao, Y., Moon, S.J., Wang, X., Ren, Q., and Montell, C. (2008). Gr64f is required in combination with other gustatory receptors for sugar detection in Drosophila. Curr Biol 18, 1797-1801. 

Kwon, Y., Shim, H.S., Wang, X., and Montell, C. (2008). Control of thermotactic behavior via coupling of a TRP channel to a phospholipase C signaling cascade. Nat Neurosci 11, 871-873.

Wang, T., Wang, X., Xie, Q., and Montell, C. (2008). The SOCS box protein STOPS is required for phototransduction through its effects on phospholipase C. Neuron 57, 56-68.

Wang, Z., Gucek, M., and Hart, G.W. (2008). Cross-talk between GlcNAcylation and phosphorylation: site-specific phosphorylation dynamics in response to globally elevated O-GlcNAc. Proc Natl Acad Sci U S A 105, 13793-13798.

Zhao, Z., Lindsay, M.E., Roy Chowdhury, A., Robinson, D.R., and Englund, P.T. (2008). p166, a link between the trypanosome mitochondrial DNA and flagellum, mediates genome segregation. EMBO J 27, 143-154.

 

2007

Jiao, Y., Moon, S.J., and Montell, C. (2007). A Drosophila gustatory receptor required for the responses to sucrose, glucose, and maltose identified by mRNA tagging. Proc Natl Acad Sci U S A 104, 14110-14115. 

Kim, S., and Coulombe, P.A. (2007). Intermediate filament scaffolds fulfill mechanical, organizational, and signaling functions in the cytoplasm. Genes Dev 21, 1581-1597.

Kim, S., Kellner, J., Lee, C.H., and Coulombe, P.A. (2007). Interaction between the keratin cytoskeleton and eEF1Bgamma affects protein synthesis in epithelial cells. Nat Struct Mol Biol 14, 982-983.

Kwon, Y., Hofmann, T., and Montell, C. (2007). Integration of phosphoinositide- and calmodulin-mediated regulation of TRPC6. Mol Cell 25, 491-503.

Liu, Y., Promeneur, D., Rojek, A., Kumar, N., Frokiaer, J., Nielsen, S., King, L.S., Agre, P., and Carbrey, J.M. (2007). Aquaporin 9 is the major pathway for glycerol uptake by mouse erythrocytes, with implications for malarial virulence. Proc Natl Acad Sci U S A 104, 12560-12564.

Wang, T., Jiao, Y., and Montell, C. (2007). Dissection of the pathway required for generation of vitamin A and for Drosophila phototransduction. J Cell Biol 177, 305-316. 


2006

Chen, C., Saxena, A.K., Simcoke, W.N., Garboczi, D.N., Pedersen, P.L., and Ko, Y.H. (2006). Mitochondrial ATP synthase. Crystal structure of the catalytic F1 unit in a vanadate-induced transition-like state and implications for mechanism. J Biol Chem 281, 13777-13783.

Kane, L.A., Yung, C.K., Agnetti, G., Neverova, I., and Van Eyk, J.E. (2006). Optimization of paper bridge loading for 2-DE analysis in the basic pH region: application to the mitochondrial subproteome. Proteomics 6, 5683-5687.

Kim, S., Wong, P., and Coulombe, P.A. (2006). A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth. Nature 441, 362-365.

Kwon, Y., and Montell, C. (2006). Dependence on the Lazaro phosphatidic acid phosphatase for the maximum light response. Curr Biol 16, 723-729.

Moon, S.J., Kottgen, M., Jiao, Y., Xu, H., and Montell, C. (2006). A taste receptor required for the caffeine response in vivo. Curr Biol 16, 1812-1817.  

Tong, X., and Coulombe, P.A. (2006). Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion. Genes Dev 20, 1353-1364.

 

2005

Fang, Q., and Shortle, D. (2005). A consistent set of statistical potentials for quantifying local side-chain and backbone interactions. Proteins 60, 90-96.

Fang, Q., and Shortle, D. (2005). Enhanced sampling near the native conformation using statistical potentials for local side-chain and backbone interactions. Proteins 60, 97-102.

Hu, Z., Cha, S.H., van Haasteren, G., Wang, J., and Lane, M.D. (2005). Effect of centrally administered C75, a fatty acid synthase inhibitor, on ghrelin secretion and its downstream effects. Proc Natl Acad Sci U S A 102, 3972-3977.

Hu, Z., Dai, Y., Prentki, M., Chohnan, S., and Lane, M.D. (2005). A role for hypothalamic malonyl-CoA in the control of food intake. J Biol Chem 280, 39681-39683.

Lee, H., Iida, T., Mizuno, A., Suzuki, M., and Caterina, M.J. (2005). Altered thermal selection behavior in mice lacking transient receptor potential vanilloid 4. J Neurosci 25, 1304-1310.

Liu, K., Kozono, D., Kato, Y., Agre, P., Hazama, A., and Yasui, M. (2005). Conversion of aquaporin 6 from an anion channel to a water-selective channel by a single amino acid substitution. Proc Natl Acad Sci U S A 102, 2192-2197.

Liu, Y., Motyka, S.A., and Englund, P.T. (2005). Effects of RNA interference of Trypanosoma brucei structure-specific endonuclease-I on kinetoplast DNA replication. J Biol Chem 280, 35513-35520.

Silver, D.L., Geisbrecht, E.R., and Montell, D.J. (2005). Requirement for JAK/STAT signaling throughout border cell migration in Drosophila. Development 132, 3483-3492.

Wang, T., Jiao, Y., and Montell, C. (2005). Dissecting independent channel and scaffolding roles of the Drosophila transient receptor potential channel. J Cell Biol 171, 685-694.

Wang, T., and Montell, C. (2005). Rhodopsin formation in Drosophila is dependent on the PINTA retinoid-binding protein. J Neurosci 25, 5187-5194.

Wang, T., Xu, H., Oberwinkler, J., Gu, Y., Hardie, R.C., and Montell, C. (2005). Light activation, adaptation, and cell survival functions of the Na+/Ca2+ exchanger CalX. Neuron 45, 367-378.  

 

2004

Chen, C., Ko, Y., Delannoy, M., Ludtke, S.J., Chiu, W., and Pedersen, P.L. (2004). Mitochondrial ATP synthasome: three-dimensional structure by electron microscopy of the ATP synthase in complex formation with carriers for Pi and ADP/ATP. J Biol Chem 279, 31761-31768.

Fang, Y., Morrell, J.C., Jones, J.M., and Gould, S.J. (2004). PEX3 functions as a PEX19 docking factor in the import of class I peroxisomal membrane proteins. J Cell Biol 164, 863-875.

Lee, S.J., and Montell, C. (2004). Light-dependent translocation of visual arrestin regulated by the NINAC myosin III. Neuron 43, 95-103.

Lee, S.J., and Montell, C. (2004). Suppression of constant-light-induced blindness but not retinal degeneration by inhibition of the rhodopsin degradation pathway. Curr Biol 14, 2076-2085.

Lee, S.J., Xu, H., and Montell, C. (2004). Rhodopsin kinase activity modulates the amplitude of the visual response in Drosophila. Proc Natl Acad Sci U S A 101, 11874-11879.  

Silver, D.L., Naora, H., Liu, J., Cheng, W., and Montell, D.J. (2004). Activated signal transducer and activator of transcription (STAT) 3: localization in focal adhesions and function in ovarian cancer cell motility. Cancer Res 64, 3550-3558.

Xu, H., Lee, S.J., Suzuki, E., Dugan, K.D., Stoddard, A., Li, H.S., Chodosh, L.A., and Montell, C. (2004). A lysosomal tetraspanin associated with retinal degeneration identified via a genome-wide screen. EMBO J 23, 811-822. 

 

2003

Fang, Q., and Shortle, D. (2003). Prediction of protein structure by emphasizing local side-chain/backbone interactions in ensembles of turn fragments. Proteins 53 Suppl 6, 486-490.

Gao, S., and Lane, M.D. (2003). Effect of the anorectic fatty acid synthase inhibitor C75 on neuronal activity in the hypothalamus and brainstem. Proc Natl Acad Sci U S A 100, 5628-5633.

Hu, Z., Cha, S.H., Chohnan, S., and Lane, M.D. (2003). Hypothalamic malonyl-CoA as a mediator of feeding behavior. Proc Natl Acad Sci U S A 100, 12624-12629.

Lee, M.G., and Pedersen, P.L. (2003). Glucose metabolism in cancer: importance of transcription factor-DNA interactions within a short segment of the proximal region og the type II hexokinase promoter. J Biol Chem 278, 41047-41058.

Lee, S.J., Xu, H., Kang, L., Amzel, M. and Montell, C. 2003. Light adaptation through phosphoinositide-regulated translocation of Drosophila visual arrestin. Neuron 39, 121-132. 

Li, X., and Gould, S.J. (2003). The dynamin-like GTPase DLP1 is essential for peroxisome division and is recruited to peroxisomes in part by PEX11. J Biol Chem 278, 17012-17020.

Silver, D.L., and Montell, D.J. (2003). A new trick for Cyclin-Cdk: activation of STAT. Dev Cell 4, 148-149.

 

2002

Bai, J., and Montell, D. (2002). Eyes absent, a key repressor of polar cell fate during Drosophila oogenesis. Development 129, 5377-5388.

Li, X., Baumgart, E., Morrell, J.C., Jimenez-Sanchez, G., Valle, D., and Gould, S.J. (2002). PEX11 beta deficiency is lethal and impairs neuronal migration but does not abrogate peroxisome function. Mol Cell Biol 22, 4358-4365.

Li, X., and Gould, S.J. (2002). PEX11 promotes peroxisome division independently of peroxisome metabolism. J Cell Biol 156, 643-651.

 

2001

Lee, S.J., and Montell, C. (2001). Regulation of the rhodopsin protein phosphatase, RDGC, through interaction with calmodulin. Neuron 32, 1097-1106. 

Liu, Y., and Montell, D.J. (2001). Jing: a downstream target of slbo required for developmental control of border cell migration. Development 128, 321-330.

Ma, L., Yamada, S., Wirtz, D., and Coulombe, P.A. (2001). A 'hot-spot' mutation alters the mechanical properties of keratin filament networks. Nat Cell Biol 3, 503-506.

Silver, D.L., and Montell, D.J. (2001). Paracrine signaling through the JAK/STAT pathway activates invasive behavior of ovarian epithelial cells in Drosophila. Cell 107, 831-841.

Wang, Z., and Englund, P.T. (2001). RNA interference of a trypanosome topoisomerase II causes progressive loss of mitochondrial DNA. EMBO J 20, 4674-4683.

Xu, X.Z., Moebius, F., Gill, D.L., and Montell, C. (2001). Regulation of melastatin, a TRP-related protein, through interaction with a cytoplasmic isoform. Proc Natl Acad Sci U S A 98, 10692-10697. 

 

2000

Bai, J., Uehara, Y., andMontell, D.J. (2000). Regulation of invasive cell behavior by taiman, a Drosophila protein related to AIB1, a steroid receptor coactivator amplified in breast cancer. Cell 103, 1047-1058.

Wang, Z., Morris, J.C., Drew, M.E., and Englund, P.T. (2000). Inhibition of Trypanosoma brucei gene expression by RNA interference using an integratable vector with opposing T7 promoters. J Biol Chem 275, 40174-40179.

Xu, X.Z., Chien, F., Butler, A., Salkoff, L., and Montell, C. (2000). TRPgamma, a drosophila TRP-related subunit, forms a regulated cation channel with TRPL. Neuron 26, 647-657. 

 

1999

Chang, C.C., Warren, D.S., Sacksteder, K.A., and Gould, S.J. (1999). PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein import. J Cell Biol 147, 761-774.

Geisbrecht, B.V., and Gould, S.J. (1999). The human PICD gene encodes a cytoplasmic and peroxisomal NADP(+)-dependent isocitrate dehydrogenase. J Biol Chem 274, 30527-30533.

Geisbrecht, B.V., Liang, X., Morrell, J.C., Schulz, H., and Gould, S.J. (1999). The mouse gene PDCR encodes a peroxisomal delta(2), delta(4)-dienoyl-CoA reductase. J Biol Chem 274, 25814-25820.

Liu, Y., Bjorkman, J., Urquhart, A., Wanders, R.J., Crane, D.I., and Gould, S.J. (1999). PEX13 is mutated in complementation group 13 of the peroxisome-biogenesis disorders. Am J Hum Genet 65, 621-634.

Liu, Y., and Montell, D.J. (1999). Identification of mutations that cause cell migration defects in mosaic clones. Development 126, 1869-1878. Ma, L., Xu, J., Coulombe, P.A., and Wirtz, D. (1999). Keratin filament suspensions show unique micromechanical properties. J Biol Chem 274, 19145-19151.

Ma, L., Xu, J., Coulombe, P.A., and Wirtz, D. (1999). Keratin filament suspensions show unique micromechanical properties. J Biol Chem 274, 19145-19151. 

 

1998

Geisbrecht, B.V., Collins, C.S., Reuber, B.E., and Gould, S.J. (1998). Disruption of a PEX1-PEX6 interaction is the most common cause of the neurologic disorders Zellweger syndrome, neonatal adrenoleukodystrophy, and infantile Refsum disease. Proc Natl Acad Sci U S A 95, 8630-8635.

Xu, X.Z., Choudhury, A., Li, X., and Montell, C. (1998). Coordination of an array of signaling proteins through homo- and heteromeric interactions between PDZ domains and target proteins. J Cell Biol 142, 545-555.

Xu, X.Z., Wes, P.D., Chen, H., Li, H.S., Yu, M., Morgan, S., Liu, Y., and Montell, C. (1998). Retinal targets for calmodulin include proteins implicated in synaptic transmission. J Biol Chem 273, 31297-31307.  

 

1997

Chang, C.C., Lee, W.H., Moser, H., Valle, D., and Gould, S.J. (1997). Isolation of the human PEX12 gene, mutated in group 3 of the peroxisome biogenesis disorders. Nat Genet 15, 385-388.

Xu, X.Z., Li, H.S., Guggino, W.B., and Montell, C. (1997). Coassembly of TRP and TRPL produces a distinct store-operated conductance. Cell 89, 1155-1164. 

 

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