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What a Difference a 'Y' Makes Panel

Pamela Ouyang, M.B.B.S - moderator
Grace Pien, M.D., M.S.C.E.
Sabra Klein, Ph.D.




Pamela Ouyang, M.B.B.S - moderatorDr. Pamela Ouyang
Professor of Medicine
Director, Women’s Cardiovascular Health Center


An attending cardiologist at the Johns Hopkins Bayview Medical Center, Dr. Pamela Ouyang cares for patients in the Coronary Intensive Care Unit and teaches students, residents and fellows from Johns Hopkins Hospital and Johns Hopkins Bayview Medical Center. She was named Program Director of the Johns Hopkins Bayview General Clinical Research Center in 2001, and in 2007 she was named a Deputy Director of the Institute for Clinical and Translational Research at Johns Hopkins.

Dr. Ouyang’s research interests focus on the vascular effects of sex hormones, subclinical atherosclerosis, and clinical trials in cardiology.  An expert on cardiovascular disease in women, Dr. Ouyang was part of a recent panel of experts who issued the 2011 Update of the American Heart Association Guidelines for the Prevention of Cardiovascular Disease in women.

Dr. Ouyang earned her medical degree at St. Bartholomew’s Hospital Medical College in London, England, and completed her residency and fellowship training in cardiology at The Johns Hopkins Hospital. 





Grace Pien, M.D., M.S.C.E.Dr. Grace Pien
Assistant Professor of Medicine

Dr. Grace Pien is assistant professor of medicine at The Johns Hopkins University School of Medicine. She is board certified in both Sleep Medicine and Pulmonary Disease.

She has co-authored over 20 publications, including on the topic of gender differences in sleep and sleep disorders.

Dr. Pien earned her medical degree from Columbia University College of Physicians and Surgeons in New York.








Sabra Klein, Ph.D.Dr. Sabra Klein
Associate Professor of Molecular Microbiology and Immunology and Biochemistry and Molecular Biology
Johns Hopkins University Bloomberg School of Public Health


Dr. Sabra Klein is a scientist who specializes in the biological differences between males and females and how these differences affect susceptibility to infection and responses to vaccination. She is recognized as a leading expert on sex differences in susceptibility to infection. Dr. Klein has published more than 85 peer-reviewed publications, co-edited the book: Sex Hormones and Immunity to Infection and currently serves as gender expert for the World Health Organization. Her current research focuses on the impact of hormones on immune responses to viruses and vaccines, and examines how immunological, hormonal and genetic differences between males and females affect sex differences in susceptibility to influenza viruses and the outcome of vaccination.

 In 2010, Dr. Klein was awarded the Society for Women’s Health Research Medtronic Prize for Scientific Contributions to Women’s Health. The annual prize was established to highlight a mid-career female scientist or engineer for her contributions to women’s health. She is a member of the Organization for the Study of Sex Differences.

Dr. Klein earned a master’s of science degree in behavioral psychology at the University of Georgia and Ph.D. in behavioral neuroscience at The Johns Hopkins University. She conducted her postdoctoral fellowship in microbiology and immunology at the Johns Hopkins University Bloomberg School of Public Health.


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