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CUSP for Mechanically Ventilated Patients

Patients on mechanical ventilation are a vulnerable subset of the intensive care unit population. Approximately 23 percent of mechanically ventilated patients suffer from a ventilator-associated condition—defined as increased oxygenation requirements —and 9.3 percent acquire ventilator-associated pneumonia, the most lethal of hospital-acquired infections. Through a contract awarded in September 2013 by the Agency for Healthcare Research and Quality, the Armstrong Institute is leading a three-year national collaborative project that aims to save patients’ lives, prevent suffering and reduce health care costs by eliminating these harms.

Seeking hospital participants: Next cohort begins in fall 2014

We are enrolling acute-care hospitals from across the United States, including Puerto Rico, in this effort to reduce ventilator-associated harms. The first two-year cohort of hospitals began in January 2014, and the second cohort is expected to begin in the fall of 2014.

Participating organizations will use evidence-based interventions to reduce ventilator-associated harms, to shorten the duration of ventilation, and to improve outcomes through such steps as getting ICU patients moving earlier. They will also adopt the Comprehensive-Unit-Based Safety Program to foster a culture of patient safety and give frontline providers the tools and support needed to tackle hazards in their care areas. 

Learn more about this opportunity to improve patient care:

For more details or to join this project, email


This initiative leverages the capabilities of other leaders in the field, including faculty from Harvard Pilgrim Health Care Institute for their scientific expertise, and MHA Keystone Center for Patient Safety and Quality for program support and coordination.

Project Portal

If your team plans to participate in this project or you would like to review presentations, tools and other content from it, you will be able to find these resources on the CUSP for Mechanically Ventilated Patients project website.

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