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The Vascular Biology Research Group represents a uniquely diverse yet closely collaborative and synergistic family of investigators. The investigative breadth and excellence is reflected in the large number of high-profile publications, as well as the funding track record of this group. The range of research endeavors spans the gamut of vascular biologic interests including: endothelial cell signaling and adhesion, vascular nitroso-redox regulation, vascular smooth muscle and adrenergic physiology, stem cell biology, and vascular communication. The techniques with which the group is facile stretch from whole animal integrated cardiovascular physiology through isolated vascular techniques (myography and video dimension analysis), fluorescent confocal microscopy and immunocytochemistry, to atomic force microscopy and functional proteomics. Through these approaches, the group has added significantly to our understanding of the pathophysiology of a number of diseases, including Raynauds phenomenon associated with scleroderma, atherosclerosis, and aging. We will continue to develop an ongoing synergy as we investigate cutting-edge tools and reagents and develop state-of-the-art techniques to answer some of the fundamental questions in vascular biology. We have the investigative breadth to understand vascular pathobiology hierarchically from molecule to man, and that is our ongoing goal and challenge.
Berkowitz, Dan – Professor and Vice Chair for Research. Research Focus: studying the mechanisms that underlie vascular disorders, with a concentration on the effect of deep-space radiation on the cardiovascular system.
Chang, Fumin – (Lab: Nick Flavahan) Research Associate.
Dodd-o, Jeff – Associate Professor. Research Focus: understanding the factors that contribute to ischemia/reperfusion injury of the lung and how ischemia/reperfusion contributes to lung dysfunction in the early post-cardiopulmonary bypass period.
Faraday, Nauder – Professor. Research Focus: translational and clinical research programs in platelet biology and perioperative genomics.
Flavahan, Nick - Professor. Research Focus: elucidating the cellular interactions and subcellular signaling pathways that control normal vascular function and regulate the initiation of vascular disease.
Gao, Wei Dong – Associate Professor. Research Focus: defining the molecular and cellular mechanisms of contractile dysfunction in the failing heart.
Hogue, Charles – Professor. Research Focus: methods to improve outcomes from cardiovascular surgery with a particular focus on brain and kidney injury.
Johns, Roger – Professor. Research Focus: investigating the mechanisms that underlie anesthesia, analgesia, chronic pain, and inflammatory lung disorders (such as pulmonary hypertension and asthma).
Koehler, Ray – Professor and Associate Director of Research. Research Focus: basic and preclinical translational research in the areas of cerebrovascular physiology and cerebral ischemic injury that arises from stroke and cardiac arrest.
Nguyen, Thai – Assistant Professor. Research Focus: Research Focus: studying the mechanisms that underlie vascular disorders, with a concentration on the effect of deep-space radiation on the cardiovascular system.
Nyhan, Dan – Professor. Research Focus: studying vascular changes, specifically those that accompany aging to determine the underlying causes and find ways to reverse the process.
Rivers, Ric – Associate Professor. Research Focus: studying microcirculation physiology to determine how metabolic demands are signaled between the tissue and the vascular network and along the vascular network itself.
Romer, Lew - Professor, Departments of Anesthesiology/Critical Care Medicine, Cell Biology, Biomedical Engineering, Pediatrics, Cell and Molecular Medicine Program, Center for Cell Dynamics.
Sapirstein, Adam – Assistant Professor. Research Focus: the roles of phospholipases A2 and their lipid metabolites in brain injury.
Shoukas, Artin – Professor (Joint appointment with Biomedical Engineering). Research Focus: studying vascular changes, specifically those that accompany aging, to determine the underlying causes and find ways to reverse the process.