Research

Health Sciences

Outcomes

  • Long and short term ICU outcomes
  • Impact of intensivists on clinical and financial outcomes
  • Impact of nurse staffing on patient outcomes
  • Reduced CRBSI
  • Evidence-based approach to extubation decision making
  • Remote intensivists impact on clinical and economic outcomes
  • Long-term outcome in patients with ARDS
  • Long-term outcomes in patients that develop Critical Illness Neuropathy during Acute lung injury (ALI)

Risk Factor Assessments

  • Risk factors for outcomes related to transfusion practice
  • Risk factors for perioperative pulmonary outcomes

Process Assessment

  • ICU structure and process relationships to clinical and economic outcomes
  • Development and implementation of quality measures in the ICU
  • Safe systems design
  • Team building
  • Family satisfaction assessments
  • Utilization of the PDSA approach in the ICU

Clinical Sciences

Sepsis

  • Antibiotics and antifungals
  • Novel therapies such as cytokine antagonists and natural anticoagulants
  • Pharmacokinetic drug dosing

ARDS

  • Low lung volume ventilation
  • Prone positioning
  • Nitric oxide
  • HFOV
  • Liquid ventilation

Cardiovascular

  • General vs regional anesthesia
  • Hypothermia
  • Supraventricular tachyarythmias
  • Perioperative hypertension
  • Perioperative stress response
  • Perioperative QT prolonagtion

Informatics

  • Web-based error reporting (ICUSRS project)
  • Computer-based point of care patient records (Eclipsys)
  • Computerized database management strategies
  • Web-based educational tools
  • Severity of illness scoring (APACHE III)
  • Videoconferencing applications

Basic Sciences

Sympathetic nervous system

  • Vasoactive drug effects
  • Control of splanchnic capacitance blood vessel tone

Hemostatic function

  • Platelet activation and aggregation
  • Interactions between coagulation and inflammatory cascades

Cytokine responses

  • TNF, IL2, IL4, IL6

Vasomotor reactivity


Pharmacogenomics

  • Perioperative molecular genetic center
  • Renal failure
  • Cardiovascular outcomes in perioperative period

Phospholipase enzyme systems.

Johns Hopkins Medicine Department of Anesthesiology & Critical Care Medicine

For his groundbreaking work in the area of patient safety, Hopkins anesthesiologist Dr. Peter Pronovost has been named by the editors of Time Magazine as one of the 100 most influential people in the world for 2008.

Peter J. Pronovost, M.D., Ph.D., FCCM

Director, Adult Critical Care Medicine Division
Director, Cardiac Surgical Intensive Care Unit
Associate Professor
Department of Anesthesiology/CCM, Surgery, and Health Policy and Management
Co-Chair Johns Hopkins Hospital Safety Committee
Director, Johns Hopkins Center for Quality, Safety & Innovation

Faculty

  • Todd Dorman, MD
  • Peter J. Pronovost, MD
  • Bradford J. Winters, MD
  • Sean M. Berenholtz, MD
  • Adam Sapirstein, MD
  • Nauder Faraday, MD
  • Julius Pham, MD
  • David Efron, MD
  • Ralph J Fuchs, MD
  • Elliott Haut, MD
  • Pamela A. Lipsett, MD
  • Eddie E. Cornwell, III, MD
  • Pedro Mendez-Tellez, MD
  • Jeff Dodd-o, MD
  • Theresa Hartsell, MD
  • Elizabeth Martinez, MD