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Research Interests
Molecular mechanisms of Th2 inflammation in the lung
Current Research
Pulmonary inflammation, particularly Th2 inflammation, is an important immune response that underlies many diseases, including asthma and COPD. Cytokines, chemokines, and other factors play important roles in initiation, regulation, and resolution of inflammation in the lung. Our laboratory is interested in understanding the molecular mechanisms and specific pathways that regulate inflammation. Our studies are focused on animal models. These include allergen sensitization and challenge models, transgenic models in which specific cytokines or factors are targeted to the lung, and natural mutant models. Using these models and techniques we will be able to identify novel molecules and pathways that mediate or regulate pulmonary inflammation. These studies will help us in testing new therapeutic strategies for the treatment of inflammatory pulmonary disease such as asthma and COPD.
Laboratory
Zhou Zhu, MD, PhD
Visiting Associate Professor of Medicine
Principal investigator
Sun-Young Oh, PhD
Postdoctoral fellow
Positions available
Postdoctoral fellow positions
Candidates should have trainings in molecular biology and immunology. Experience in animal models, particularly in pulmonary diseases will be helpful.
Contact: Dr. Zhu at 410-550-2342 or send CV via email: zzhu@jhmi.edu.
Updated November 2006
