Evaluate sialidase delivery as
a therapeutic for spinal cord injury
Evaluate the effects of multiple
inhibitors on axon regeneration in CNS lesion models
Current Projects:
Enhancing axon regeneration in vivo using multi-inhibitor blocking (with Dr. Lawrence Schramm)
Evaluate sialidase delivery as
a therapeutic for spinal cord injury
Evaluate the effects of multiple
inhibitors on axon regeneration in CNS lesion models
Ganglioside recognition by myelin-associated glycoprotein (MAG) - Molecular specificity and biological functions
Ganglioside function in the brain
Using mice genetically engineered to lack complex gangliosides we are studying...
Nerve degeneration and dysmyelination
Motor behavioral deficits
Alterations in myelin neurochemistry and biochemistry
Glycans and glycan binding proteins in inflammation (with Drs. Bruce Bochner and Kostas Konstantopoulos)
Endogenous ligands for
Siglecs and Selectins on human neutrophils and eosinophils
Role of glycans in the control of allergic
inflammation
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