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Selected Publications

Hobbs R, Sgouros G. Calculation of the biological effective dose for piecewise defined dose-rate fits. Med. Phys. 36, 904 (2009), DOI:10.1118/1.3 Download

Baechler S, Hobbs RF, Prideaux AR, Wahl RL, Sgouros G. Extension of the biological effective dose to the MIRD schema and possible implications in radionuclide therapy dosimetry.Med. Phys. 35, 1123 (2008), DOI:10.1118/1.2836421 Download

Prideaux AR, Song H, Hobbs RF, He B, Frey EC, Ladenson PW, Wahl RL, Sgouros G. Three-Dimensional Radiobiologic Dosimetry: Application of Radiobiologic Modeling to Patient-Specific 3-Dimensional Imaging-Based Internal Dosimetry. J Nucl Med. 2007 Jun;48(6):1008-1016. Epub 2007 May 15. Download
Sgouros G. Toward patient-friendly cell-level dosimetry. J Nucl Med. 2007 Apr;48(4):496-7 Download
Song H, Du Y, Sgouros G, Prideaux A, Frey E, Wahl RL. Therapeutic potential of 90Y- and 131I-labeled anti-CD20 monoclonal antibody in treating non-Hodgkin's lymphoma with pulmonary involvement: a Monte Carlo-based dosimetric analysis. J Nucl Med. 2007 Jan;48(1):150-7.? Download
Song H, He B, Prideaux A, Du Y, Frey E, Kasecamp W, Ladenson PW, Wahl RL, Sgouros G. Lung dosimetry for radioiodine treatment planning in the case of diffuse lung metastases. J Nucl Med. 2006 Dec;47(12):1985-94. Download
Sgouros G, Song H, Ladenson PW, Wahl RL. Lung toxicity in radioiodine therapy of thyroid carcinoma: development of a dose-rate method and dosimetric implications of the 80-mCi rule. J Nucl Med. 2006 Dec;47(12):1977-84.
Jaggi JS, Seshan SV, McDevitt MR, Sgouros G, Hyjek E, Scheinberg DA. Mitigation of radiation nephropathy after internal alpha-particle irradiation of kidneys. Int J Radiat Oncol Biol Phys. 2006 Apr 1;64(5):1503-12. Epub 2006 Feb 28.
Kostarelos K, Emfietzoglou D, Papakostas A, Yang WH, Ballangrud AM, Sgouros G. Engineering lipid vesicles of enhanced intratumoral transport capabilities: correlating liposome characteristics with penetration into human prostate tumor spheroids. J Liposome Res. 2005;15(1-2):15-27.??
Siegel JA, Sparks RB, Sharkey RM, Wessels BW, Bolch WE, Bouchet LG, Breitz HB, Meredith RF, Sgouros G, Stabin MG. Blood-based red marrow dosimetry: where's the beef? J Nucl Med. 2005 Aug;46(8):1404-6; author reply 1405-6.
Watchman CJ, Jokisch DW, Patton PW, Rajon DA, Sgouros G, Bolch WE. Absorbed fractions for alpha-particles in tissues of trabecular bone: considerations of marrow cellularity within the ICRP reference male. J Nucl Med. 2005 Jul;46(7):1171-85.?
Jaggi JS, Seshan SV, McDevitt MR, LaPerle K, Sgouros G, Scheinberg DA. Renal tubulointerstitial changes after internal irradiation with alpha-particle-emitting actinium daughters. J Am Soc Nephrol. 2005 Sep;16(9):2677-89. Epub 2005 Jun 29.?
Jaggi JS, Kappel BJ, McDevitt MR, Sgouros G, Flombaum CD, Cabassa C, Scheinberg DA. Efforts to control the errant products of a targeted in vivo generator. Cancer Res. 2005 Jun 1;65(11):4888-95.
Sgouros G. Dosimetry of Internal Emitters. J Nucl Med 2005;46:18S-27S. Download
Kostarelos K, Emfietzoglou D, Papakostas A, Yang W-H, Ballangrud ?M, Sgouros G.? Binding and interstitital penetration of liposomes within avascular tumor spheroids.? Int J Cancer, 2004 Nov 20;112(4):713. Download
Sgouros G, Kolbert KS, Sheikh A, Pentlow KS, Mun EF, Barth A, Robbins RJ, Larson SM.? Patient-specific dosimetry for ¹³¹I thyroid cancer therapy using ¹²⁴I-PET and 3D-ID.? J Nucl Med, 2004; 45:1366-72. Download
Ballangrud ?M, Yang W-H, Palm S, Enmon R, Borchardt PE, Pellegrini VA, McDevitt MR, Scheinberg DA, Sgouros G.? Alpha-particle emitting atomic generator (²²⁵Ac)-labeled Trastuzumab (Herceptin) targeting of breast cancer spheroids: Efficacy versus HER2/neu expression.? Clin Cancer Res, 2004; 10:4489-97. Download
Sofou S, Thomas JL, Lin H, McDevitt MR, Scheinberg DA, Sgouros G.? Engineered liposomes for potential a-particle therapy of metastatic cancer.? J Nucl Med 2004; 45:253-260. (PDF version)
Enmon R, Yang W, Ballangrud ?M, Solit DB, Heller G, Rosen N, Scher HI, Sgouros G.? Combination treatment with 17AAG and acute irradiation produces supra-additive growth suppression in human prostate carcinoma spheroids.? Cancer Res 2003; 63: 8393-8399. Download
Palm S, Enmon RM, Matei C, Kolbert KS, Xu S, Pellegrini V, Zanzonico PB, Finn RL, Koutcher JA, Larson SM, Sgouros G.? Pharmacokinetics and biodistribution of ⁸⁶Y-Trastuzumab for ⁹⁰Y dosimetry in an ovarian carcinoma model: Correlative microPET and MRI.? J Nucl Med 2003; 44:1148-1155. Download
Sgouros G, Squeri S, Ballangrud ?M, Kolbert KS, Teitcher JB, Panageas KS, Finn RD, Divgi CR, Larson SM, Zelenetz AD.? Patient-Specific, 3-D dosimetry in Non-Hodgkin?s Lymphoma Patients Treated with ¹³¹I-anti-B1 Antibody: Assessment of tumor dose-response.? J Nucl Med 2003; 44:260-268. Download
O'Donoghue JA, Baidoo N, Deland D, Welt S, Divgi CR, Sgouros G.? Hematologic toxicity in radioimmunotherapy: Dose-response relationships in I-131 labeled antibody therapy. Cancer Biother Radiopharm 2002; 17:435-443. Download
Ballangrud AM, Yang W, Charlton DE, McDevitt MR, Hamacher KA, Panageas KS, Ma D, Bander NH, Scheinberg DA, Sgouros G.? Response of LNCaP spheroids following treatment with alpha-particle emitter (²¹³Bi)-labeled anti-PSMA antibody (J591).? Cancer Res 2001; 61:2008-2014. Download
Sgouros G, Stabin M, Erdi Y, Akabani G, Kwok C, Brill AB, Wessels B.? Red marrow dosimetry for radiolabeled antibodies that bind to marrow, bone or blood components.? Med Phys 2000; 27:2150-2164. Download
Sgouros G, Ballangrud ?M, Humm JL, Jurcic JG, McDevitt MR, Erdi YE, Mehta BM, Finn RD, Geerlings MW, Larson SM, Scheinberg DA.? Pharmacokinetics and dosimetry of an alpha-particle emitter labeled antibody: ²¹³Bi-HuM195 (anti-CD33) in patients with leukemia.? J Nucl Med, 1999; 40:1935-1946. Download